The Division of BMT&CT's translational research mission focuses on developing new cellular therapy programs and testing the use of bone marrow transplantation following solid organ transplantation to establish immunity, extend organ survival and achieve eventual tolerance. Some of our patients come to Pittsburgh as their last hope after being too sick to be treated anywhere else.

Our division's laboratory-based research mission focuses on elucidating mechanisms of alloreactivity (the biological principle driving graft-versus-host-disease [GVHD] and rejection) and mechanisms essential for successful tolerance. These studies will help us design new and better drugs and immunotherapy interventions.