Our Research

The overarching theme of our center is Respiratory Epithelial Biology, exploring its functions, its response to infections, and testing treatments to improve its CF phenotype.
This includes (1) CFTR and ion transport, (2) the airway surface microenvironment and mucociliary clearance, (3) infections at the epithelial interface and (4) immune-epithelial cell defects that contribute to CF pathogenesis.  The areas of research emphasis and the CF investigator groups that advance this vision are described below. These research relationships are enhanced by four cores: Human Airway Cells and Tissues, Assays, Infection and Immunity and Translational Studies.