Pediatric Institute for Heart Regeneration and Therapeutics

Essential Publications

Cardiac Regeneration: Methods and Protocols (ed. Kühn B, Poss K).

Lamin B2 levels regulate polyploidization of cardiomyocyte nuclei and myocardial regeneration.  Han L, Choudhury S, Mich-Basso JD, Ammanamanchi N, Ganapathy G, Suresh S, Khaladkar M, Singh J, Maehr R, Zuppo DA, Kim J, Eberwine JH, Wyman SK, Wu Y & Kühn B. Dev. Cell 2020; 6;53(1):42-59. PMID: 32109383, PMCID: PMC7346764.

• Alexander Y. Payumo and Guo N. Huang. (2020) Lamin B2, Guardian of Cardiomyocyte Nuclear Division. Developmental Cell.

Control of Cytokinesis by β-adrenergic Receptors Indicates an Approach for Regulating Cardiomyocyte Endowment. Liu H, Zhang CH, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D, Ganapathy B, Guillermier C, Chen N, Khaladkar M, Spaethling J, Eberwine JH, Kim J, Walsh S, Choudhury S, Little K, Francis K, Sharma M, Viegas M, Bais A, Kostka D, Ding J, Bar-Joseph Z, Wu Y, Yechoor V, Moulik M, Johnson J, Weinberg J, Reyes-Múgica M, Steinhauser ML, Kühn B. Science Translational Medicine. 2019 Oct 9.

• Katherine E. Yutzey. (2020) Cytokinesis, Beta-Blockers, and Congential Heart Disease. The New England Journal of Medicine. 

• Olaf Bergmann. (2020) Cardiomyocytes in congenital heart disease: Overcoming cytokinesis failure in tetralogy of Fallot. The Journal of Thoracic and Cardiovascular Surgery. 

• Nicholas D. Andersen, Joseph W. Turek. (2020) Commentary: Targeting cytokinesis failure in tetralogy of Fallot: Late to the dance?. The Journal of Thoracic and Cardiovascular Surgery.