Dr. Byersdorfer is a physician-scientist whose research interests focus on understanding the biology of GVHD-causing T cells following allogeneic transplantation. The goal of these efforts is to develop novel therapeutics to mitigate graft-versus-host disease (GVHD) while preserving homeostatic immune reconstitution and graft-versus-leukemia effects. Specifically, Dr. Byersdorfer’s research program seeks to elucidate the specific metabolic pathways that are upregulated in GVHD-causing T cells. His efforts represent a novel approach to understand disease pathogenesis and will likely lead to new and innovative therapies. In addition, his findings on T cell metabolism will almost certainly have implications beyond the field of blood and marrow transplantation to impact solid organ transplantation and improve our ability to mediate long-term anti-leukemia responses.
- Craig A. Byersdorfer, MD, PhD - Principal Investigator
- Darlene Monlish, PhD
- Erica Lynne Braverman, MD
- Archana Rampogal
- Rachael Teodorescu
- Margaret McQuaid
- Manda Ramsey
The Byersdorfer Lab welcomes graduate students for rotations in the lab, clinical fellows interested in immune cell metabolism, and medical students as part of the Dean’s Summer Research Program.