Recent Publications

2020

Melanie A. Krook, Alexandria Lenyo, Max Wilberding, Hannah Barker, Mikayla Dantuon, Kelly M. Bailey, Hui-Zi Chen, Julie W. Reeser, Michele, R. Wing, Jharna Miya, Eric Samorodnitsky, Amy M. Smith, Thuy Dao, Dorrelyn M. Martin, Kristen K. Ciombor, John Hays, Aharon G. Freud and Sameek Roychowdhury. Efficacy of FGFR Inhibitors and Combination Therapies for Acquired Resistance in FGFR2-Fusion Cholangiocarcinoma. DOI: 10.1158/1535-7163.MCT-19-0631 Published March 2020.

Mark T Vander Lugt, Xiaohua Chen, Maria L Escolar, Beth A Carella, Jessie L Barnum, Randy M Windreich, Memphis J Hill, Michelle Poe, Rebecca A Marsh, Heather Stanczak, Elizabeth O Stenger, Paul Szabolcs. Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders. Blood Adv. 2020 Jul 14;4(13):3041-3052. doi: 10.1182/bloodadvances.2020001940.

Lauri M. Burroughs, Aleksandra Petrovic, Ruta Brazauskas, Xuerong Liu, Linda M. Griffith, Hans D. Ochs, Jack J. Bleesing, Stephanie Edwards, Christopher C. Dvorak, Sonali Chaudhury, Susan E. Prockop, Ralph Quinones, Frederick D. Goldman, Troy C. Quigg, Shanmuganathan Chandrakasan, Angela R. Smith, Suhag Parikh, Blachy J. Dávila Saldaña, Monica S. Thakar, Rachel Phelan, Shalini Shenoy, Lisa R. Forbes, Caridad Martinez, Deepak Chellapandian, Evan Shereck, Holly K. Miller, Neena Kapoor, Jessie L. Barnum, Hey Chong, David C. Shyr, Karin Chen, Rolla Abu-Arja, Ami J. Shah, Katja G. Weinacht, Theodore B. Moore, Avni Joshi, Kenneth B. DeSantes, Alfred P. Gillio, Geoffrey D. E. Cuvelier, Michael D. Keller, Jacob Rozmus, Troy Torgerson, Michael A. Pulsipher, Elie Haddad, Kathleen E. Sullivan, Brent R. Logan, Donald B. Kohn, Jennifer M. Puck, Luigi D. Notarangelo, Sung-Yun Pai, David J. Rawlings, Morton J. Cowan. Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report. Blood. 2020 Jun 4;135(23):2094-2105. doi: 10.1182/blood.2019002939.

James Felker, Alberto Broniscer. Improving long-term survival in diffuse intrinsic pontine glioma.  Expert Rev Neurother. 2020 Jul;20(7):647-658. doi: 10.1080/14737175.2020.1775584. Epub 2020 Jun 16.

Stewart Goldman, Ian F Pollack, Regina I Jakacki, Catherine A Billups, Tina Y Poussaint, Adekunle M Adesina, Ashok Panigrahy, Donald W Parsons, Alberto Broniscer, Giles W Robinson, Nathan J Robison, Sonia Partap, Lindsay B Kilburn, Arzu Onar-Thomas, Ira J Dunkel, Maryam Fouladi. Phase II study of peginterferon alpha-2b for patients with unresectable or recurrent craniopharyngiomas: a Pediatric Brain Tumor Consortium report. Neuro-Oncology, noaa119, 11 May 2020 https://doi.org/10.1093/neuonc/noaa119.

Jason Chiang , Alexander K. Diaz , Lydia Makepeace, Xiaoyu Li , Yuanyuan Han , Yimei Li , Paul Klimo Jr, Frederick A. Boop, Suzanne J. Baker , Amar Gajjar , Thomas E. Merchant , David W. Ellison , Alberto Broniscer, Zoltan Patay and Christopher L. Tinkle. Clinical, imaging, and molecular analysis of pediatric pontine tumors lacking characteristic imaging features of DIPG. Acta Neuropathol Commun. 2020 Apr 23;8(1):57. doi: 10.1186/s40478-020-00930-9. PMID: 32326973

Gourish Mondal, Julieann C. Lee, Ajay Ravindranathan, Javier E. Villanueva-Meyer, Quynh T. Tran, Sariah J. Allen, Jairo Barreto, Rohit Gupta, Pamela Doo, Jessica Van Ziffle, Courtney Onodera, Patrick Devine, James P. Grenert, David Samuel, Rong Li, Laura K. Metrock, Lee-way Jin, Reuben Antony, Mouied Alashari, Samuel Cheshier, Nicholas S. Whipple, Carol Bruggers, Corey Raffel, Nalin Gupta, Cassie N. Kline, Alyssa Reddy, Anu Banerjee, Matthew D. Hall, Minesh P. Mehta, Ziad Khatib, Ossama M. Maher, Carole Brathwaite, Melike Pekmezci, Joanna J. Phillips, Andrew W. Bollen, Tarik Tihan, John T. Lucas Jr, Alberto Broniscer, Mitchel S. Berger, Arie Perry, Brent A. Orr & David A. Solomon. Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Acta Neuropathologica volume 139, pages1071–1088(2020). Published: 17 April 2020

Patricia A Baxter, Jack M Su, Arzu Onar-Thomas, Catherine A Billups, Xiao-Nan Li, Tina Young Poussaint, Edward R Smith, Patrick Thompson, Adekunle Adesina, Pete Ansell, Vincent Giranda, Arnold Paulino, Lindsey Kilburn, Ibrahim Quaddoumi, Alberto Broniscer, Susan M Blaney, Ira J Dunkel, Maryam Fouladi. A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study. Neuro-Oncology, Volume 22, Issue 6, June 2020, Pages 875–885. Published:03 February 2020.

Rakesh Sindhi, Vinayak Rohan, Andrew Bukowinski, Sameh Tadros, Jean de Ville de Goyet, Louis Rapkin, and Sarangarajan Ranganathan. Liver Transplantation for Pediatric Liver Cancer. Cancers (Basel). 2020 Mar 19;12(3):720. doi: 10.3390/cancers12030720.

Li Wen, Tanveer A Javed, Andrea K Dobbs, Rebecca Brown, Mengya Niu, Liwen Li, Asna Khalid, Monique Barakat, Xiangwei Xiao, Dean Yimlamai, Liza Konnikova, Mang Yu, Craig A Byersdorfer, Sohail Z Husain. Protective Effects of Calcineurin on Pancreatitis in Mice Depend on Cellular Source.  Gastroenterology. 2020 May 20;S0016-5085(20)34704-1. doi: 10.1053/j.gastro.2020.05.051.

Mark T Vander Lugt, Xiaohua Chen, Maria L Escolar, Beth A Carella, Jessie L Barnum, Randy M Windreich, Memphis J Hill, Michelle Poe, Rebecca A Marsh, Heather Stanczak, Elizabeth O Stenger, Paul Szabolcs. Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders. Blood Adv. 2020 Jul 14;4(13):3041-3052. doi: 10.1182/bloodadvances.2020001940.

Madison Remick, Michael M McDowell, Kanupriya Gupta, James Felker, Taylor J Abel. Emerging indications for stereotactic laser interstitial thermal therapy in pediatric neurosurgery.  Int J Hyperthermia. 2020 Jul;37(2):84-93. doi:10.1080/02656736.2020.1769868.

James Felker, Alberto Broniscer. Improving long-term survival in diffuse intrinsic pontine glioma.  Expert Rev Neurother. 2020 Jul;20(7):647-658. doi: 10.1080/14737175.2020.1775584. Epub 2020 Jun 16.

Hanna Algattas, Hussam Abou-Al-Shaar, Michael Mendelson, Georgianne L Arnold, James Felker, Julia Meade, Stephanie Greene. Familial Cerebral Cavernous Malformation Syndrome with Concomitant Fourth Ventricular Ependymoma: True Association or Mere Coincidence? Cancer Genet. 2020 Jun;244:36-39. doi: 10.1016/j.cancergen.2020.04.075. Epub 2020 May 3.

Meghan McCormick, Erika Friehling,  Ramasubramanian Kalpatthi,  Nalyn Siripong,  Kenneth Smith. Cost‐effectiveness of levofloxacin prophylaxis against bacterial infection in pediatric patients with acute myeloid leukemia. Pediatr Blood Cancer. 2020 Jul 25;e28469. doi: 10.1002/pbc.28469. Online ahead of print.

Allison G Close, Amita Ghuman, Erika Friehling, Megan Hamm, Natasha N Frederick, Elizabeth Miller, Traci M Kazmerski. Experiences with Menses and Menstrual Suppression of Young Women with a History of Cancer. J Adolesc Young Adult Oncol. 2020 Feb;9(1):23-29. doi: 10.1089/jayao.2019.0077. Epub 2019 Oct 8.

Meghan McCormick, Erika Friehling,  Ramasubramanian Kalpatthi,  Nalyn Siripong,  Kenneth Smith. Cost‐effectiveness of levofloxacin prophylaxis against bacterial infection in pediatric patients with acute myeloid leukemia. Pediatr Blood Cancer. 2020 Jul 25;e28469. doi: 10.1002/pbc.28469. Online ahead of print.

Meghan C. McCormick,  Eleanor Sharp,  Ramasubramanian Kalpatthi,  James Zullo,  Nursen Gurtunca,  Jun Zhang,  Robert Krafty,  Sripriya Raman. Hyperglycemia requiring insulin during acute lymphoblastic leukemia induction chemotherapy is associated with increased adverse outcomes and healthcare costs. Pediatr Blood Cancer. 2020 Jun 26;e28475. doi: 10.1002/pbc.28475. Online ahead of print.

Ram Kalpatthi MD and Joseph E. Kiss MD. Thrombotic Thrombocytopenic Purpura, Heparin-Induced Thrombocytopenia, and Disseminated Intravascular Coagulation. Crit Care Clin. 2020 Apr;36(2):357-377. doi: 10.1016/j.ccc.2019.12.006. Epub 2020 Feb 6.

Meghan McCormick  Troy Richardson  Bradley A. Warady  Enrico M. Novelli  Ramasubramanian Kalpatthi. Acute kidney injury in paediatric patients with sickle cell disease is associated with increased morbidity and resource utilization. Br J Haematol. 2020 May;189(3):559-565. doi: 10.1111/bjh.16384. Epub 2020 Feb 6.

Jing Cheng, Linda R Klei, Nathaniel E Hubel, Ming Zhang, Rebekka Schairer, Lisa M Maurer, Hanna B Klei, Heejae Kang, Vincent J Concel, Phillip C Delekta, Eric V Dang, Michelle A Mintz, Mathijs Baens, Jason G Cyster, Narayanan Parameswaran, Margot Thome, Peter C Lucas, Linda M McAllister-Lucas. GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein.  J Clin Invest. 2020 Feb 3;130(2):1036-1051. doi: 10.1172/JCI97040.

Laura C. McNamara, William Okoniewski, Scott H. Maurer, Krissy Moehling, Daniel E. Hall & Yael Schenker. “Give them the door but don’t push them through it”: Family Attitudes Toward Physician-Led Spiritual Care in Pediatric Palliative Medicine. J Relig Health. 2020 Feb 12. doi: 10.1007/s10943-020-00991-z. Online ahead of print.

Bryce B Reeve, PhD, Molly McFatrich, MPH, Jennifer W Mack, MD, MPH, Scott H Maurer, MD, Shana S Jacobs, MD, David R Freyer, DO, MS, Janice S Withycombe, PhD, RN, MN, Justin N Baker, MD, FAAP, FAAHPM, Sharon M Castellino, MD, MSc, Li Lin, MS, Nicole R Lucas, BS, Pamela S Hinds, PhD, RN, FAAN. Validity and Reliability of the Pediatric Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events. J Natl Cancer Inst. 2020 Jan 30;djaa016. doi: 10.1093/jnci/djaa016. Online ahead of print.

Molly McFatrich, Jennifer Brondon, Nicole R Lucas, Pamela S Hinds, Scott H Maurer, Jennifer W Mack, David R Freyer, Shana S Jacobs, Justin N Baker, Catriona Mowbray, Mian Wang, Sharon M Castellino, Allison Barz Leahy, Bryce B Reeve. Mapping child and adolescent self-reported symptom data to clinician-reported adverse event grading to improve pediatric oncology care and research. Cancer. 2020 Jan 1;126(1):140-147. doi: 10.1002/cncr.32525. Epub 2019 Sep 25.

Danielle N Alfano, Linda R Klei, Hanna B Klei, Matthew Trotta, Peter J Gough, Kevin P Foley, John Bertin, Tina L Sumpter, Peter C Lucas, Linda M McAllister-Lucas. MALT1 Protease Plays a Dual Role in the Allergic Response by Acting in Both Mast Cells and Endothelial Cells. J Immunol. 2020 May 1;204(9):2337-2348. doi: 10.4049/jimmunol.1900281. Epub 2020 Mar 25.

Jing Cheng, Linda R Klei, Nathaniel E Hubel, Ming Zhang, Rebekka Schairer, Lisa M Maurer, Hanna B Klei, Heejae Kang, Vincent J Concel, Phillip C Delekta, Eric V Dang, Michelle A Mintz, Mathijs Baens, Jason G Cyster, Narayanan Parameswaran, Margot Thome, Peter C Lucas, Linda M McAllister-Lucas. GRK2 suppresses lymphomagenesis by inhibiting the MALT1 proto-oncoprotein.  J Clin Invest. 2020 Feb 3;130(2):1036-1051. doi: 10.1172/JCI97040.

Hanna Algattas, Hussam Abou-Al-Shaar, Michael Mendelson, Georgianne L Arnold, James Felker, Julia Meade, Stephanie Greene. Familial Cerebral Cavernous Malformation Syndrome with Concomitant Fourth Ventricular Ependymoma: True Association or Mere Coincidence? Cancer Genet. 2020 Jun;244:36-39. doi: 10.1016/j.cancergen.2020.04.075. Epub 2020 May 3.

Jordan Mandel, Raghunandan Avula, Edward V Prochownik. Sequential analysis of transcript expression patterns improves survival prediction in multiple cancers. BMC Cancer. 2020 Apr 7;20(1):297. doi: 10.1186/s12885-020-06756-x.

Li Gu, Yahui Zhu, Xi Lin, Bingjun Lu, Xinyi Zhou, Feng Zhou, Qiu Zhao, Edward V Prochownik, Youjun Li. The IKKβ-USP30-ACLY Axis Controls Lipogenesis and Tumorigenesis. Hepatology. 2020 Mar 27. doi: 10.1002/hep.31249. Online ahead of print.

Yahui Zhu, Li Gu, Xi Lin, Cheng Liu, Bingjun Lu, Kaisa Cui, Feng Zhou, Qiu Zhao, Edward V Prochownik, Chengpeng Fan, Youjun Li. Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis. Mol Cell. 2020 Jan 2;77(1):138-149.e5. doi: 10.1016/j.molcel.2019.10.015. Epub 2019 Nov 14.

Rakesh Sindhi, Vinayak Rohan, Andrew Bukowinski, Sameh Tadros, Jean de Ville de Goyet, Louis Rapkin, and Sarangarajan Ranganathan. Liver Transplantation for Pediatric Liver Cancer. Cancers (Basel). 2020 Mar 19;12(3):720. doi: 10.3390/cancers12030720.

Mark T Vander Lugt, Xiaohua Chen, Maria L Escolar, Beth A Carella, Jessie L Barnum, Randy M Windreich, Memphis J Hill, Michelle Poe, Rebecca A Marsh, Heather Stanczak, Elizabeth O Stenger, Paul Szabolcs. Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders. Blood Adv. 2020 Jul 14;4(13):3041-3052. doi: 10.1182/bloodadvances.2020001940.

Xiaohua Chen, Memphis Hill, Mark Vander Lugt, Maria Escolar, Zhou Fang, Wei Chen, Paul Szabolcs. Rapid reconstitution of regulatory T-cell subsets is associated with reduced rates of acute graft-versus-host disease and absence of viremia after cord blood transplantation in children with reduced-intensity conditioning using alemtuzumab. Cytotherapy. 2020 Mar;22(3):149-157. doi: 10.1016/j.jcyt.2020.01.005. Epub 2020 Feb 21.

Mark T Vander Lugt, Xiaohua Chen, Maria L Escolar, Beth A Carella, Jessie L Barnum, Randy M Windreich, Memphis J Hill, Michelle Poe, Rebecca A Marsh, Heather Stanczak, Elizabeth O Stenger, Paul Szabolcs. Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders. Blood Adv. 2020 Jul 14;4(13):3041-3052. doi: 10.1182/bloodadvances.2020001940.

Mark T Vander Lugt, Xiaohua Chen, Maria L Escolar, Beth A Carella, Jessie L Barnum, Randy M Windreich, Memphis J Hill, Michelle Poe, Rebecca A Marsh, Heather Stanczak, Elizabeth O Stenger, Paul Szabolcs. Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for nonmalignant disorders. Blood Adv. 2020 Jul 14;4(13):3041-3052. doi: 10.1182/bloodadvances.2020001940.

2019

Caitlin M. Burk MD, Kara E. Coffey MD, Emily M. Mace PhD, Bret L. Bostwick MD, Ivan K. Chinn MD, Zeynep H. Coban-Akdemir PhD, Shalini N. Jhangiani MSc, James R. Lupski MD, PhD, Damara Ortiz MD, Jessie L. Barnum MD, Steven W. Allen MD, Leanna-Marie Robertson MD, Jordan S. Orange MD, PhD and Hey J. Chong MD, PhD. Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome with NK dysfunction and EBV-driven malignancy treated with stem cell transplantation. Journal of Allergy and Clinical Immunology: In Practice, 2020-03-01, Volume 8, Issue 3, Pages 1103-1106.e3, Epub 2019 Sep 11.

Allegra G. Hawkins, Claire M. Julian, Sonja Konzen, Sydney Treichel, Elizabeth R. Lawlor and Kelly M. Bailey. Microenvironmental Factors Drive Tenascin C and Src Cooperation to Promote Invadopodia Formation in Ewing Sarcoma. Neoplasia. 2019 Oct; 21(10): 1063–1072. Published online 2019 Sep 13.

J. Randall McAuley, Kelly M. Bailey, Prasanna Ekambaram, Linda R. Klei, Heejae Kang, Dong Hu, Tanner J. Freeman, Vincent J. Concel, Nathaniel E. Hubel, Jia-Ying (Lloyd) Lee, Hanna B. Klei, Jing Cheng, Preethiya Sekar, Rachel E. Bridwell, Lidija Covic, Peter C. Lucas & Linda M. McAllister-Lucas. MALT1 is a critical mediator of PAR1-driven NF-κB activation and metastasis in multiple tumor types. Oncogene volume 38, pages7384–7398(2019). Published: 16 August 2019.

Rosemarie E. Venier, Lisa M. Maurer, Elena M. Kessler, Sarangarajan Ranganathan,  Richard L. McGough, Kurt R. Weiss, Marcus M. Malek, Julia Meade, Jean M. Tersak,  Kelly M. Bailey. A germline BARD1 mutation in a patient with Ewing Sarcoma: Implications for familial testing and counseling. Pediatric Blood & Cancer. Volume 66, Issue 9. First published: 03 June 2019. 

Caitlin M. Burk MD, Kara E. Coffey MD, Emily M. Mace PhD, Bret L. Bostwick MD, Ivan K. Chinn MD, Zeynep H. Coban-Akdemir PhD, Shalini N. Jhangiani MSc, James R. Lupski MD, PhD, Damara Ortiz MD, Jessie L. Barnum MD, Steven W. Allen MD, Leanna-Marie Robertson MD, Jordan S. Orange MD, PhD and Hey J. Chong MD, PhD. Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome with NK dysfunction and EBV-driven malignancy treated with stem cell transplantation. Journal of Allergy and Clinical Immunology: In Practice, 2020-03-01, Volume 8, Issue 3, Pages 1103-1106.e3, Epub 2019 Sep 11.

Robert F. Koncar, Brittany R. Dey, Ann-Catherine J. Stanton, Nishant Agrawal, Michelle L. Wassell, Lauren H. McCarl, Abigail. L. Locke, Lauren Sanders, Olena Morozova-Vaske, Max I. Myers, Ronald L. Hamilton, Angel M. Carcaboso, Gary Kohanbash, Baoli Hu, Nduka M. Amankulor, James Felker, Madhuri Kambhampati, Javad Nazarian, Oren J. Becher, C. David James, Rintaro Hashizume, Alberto Broniscer, Ian F. Pollack and Sameer Agnihotri. Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas. Cancer Res. 2019 Aug 15;79(16):4026-4041. doi: 10.1158/0008-5472.CAN-18-3521. Epub 2019 Jun 14.

White M.D., McDowell M.M., Pearce T.M., Bukowinski A.J., Greene S. Intracranial Myxoid Mesenchymal Tumor with Rare EWSR1-CREM Translocation. Pediatr Neurosurg. 2019;54(5):347-353. doi: 10.1159/000501695. Epub 2019 Aug 20.

Jillian Lapinski, Lisa M Maurer, Margaret V Ragni, Cheryl McShea, James D Cooper, Frederico Xavier. Unsuspected Lyme disease presenting in refractory haemophilic haemarthrosis. Haemophilia. 2019 Sep;25(5):e331-e333. doi: 10.1111/hae.13821. Epub 2019 Jul 29.

Robert F. Koncar, Brittany R. Dey, Ann-Catherine J. Stanton, Nishant Agrawal, Michelle L. Wassell, Lauren H. McCarl, Abigail. L. Locke, Lauren Sanders, Olena Morozova-Vaske, Max I. Myers, Ronald L. Hamilton, Angel M. Carcaboso, Gary Kohanbash, Baoli Hu, Nduka M. Amankulor, James Felker, Madhuri Kambhampati, Javad Nazarian, Oren J. Becher, C. David James, Rintaro Hashizume, Alberto Broniscer, Ian F. Pollack and Sameer Agnihotri. Identification of Novel RAS Signaling Therapeutic Vulnerabilities in Diffuse Intrinsic Pontine Gliomas. Cancer Res. 2019 Aug 15;79(16):4026-4041. doi: 10.1158/0008-5472.CAN-18-3521. Epub 2019 Jun 14.

Allison G Close, Kelley A Jones, Allison Landowski, Galen E Switzer, Traci M Kazmerski, Elizabeth Miller, Erika Friehling. Current practices in menstrual management in adolescents with cancer: A national survey of pediatric oncology providers. Pediatr Blood Cancer. 2019 Dec;66(12):e27961. doi: 10.1002/pbc.27961. Epub 2019 Aug 23.

Ibrahim A Ahmed, Midhat S Farooqi, Mark T Vander Lugt, Jessica Boklan, Melissa Rose, Erika D Friehling, Brandon Triplett, Kenneth Lieuw, Blachy Davila Saldana, Christine M Smith, Jason R Schwartz, Rakesh K Goyal. Outcomes of Hematopoietic Cell Transplantation in Patients with Germline SAMD9/SAMD9L Mutations. Biol Blood Marrow Transplant. 2019 Nov;25(11):2186-2196. doi: 10.1016/j.bbmt.2019.07.007. Epub 2019 Jul 12.

Deirdre Nolfi-Donegan, Tirthadipa Pradhan-Sundd, Kirkwood A Pritchard Jr, Cheryl A Hillery. Redox Signaling in Sickle Cell Disease. Curr Opin Physiol. 2019 Jun;9:26-33. doi: 10.1016/j.cophys.2019.04.022. Epub 2019 May 2.

Jillian Lapinski, Lisa M Maurer, Margaret V Ragni, Cheryl McShea, James D Cooper, Frederico Xavier. Unsuspected Lyme disease presenting in refractory haemophilic haemarthrosis. Haemophilia. 2019 Sep;25(5):e331-e333. doi: 10.1111/hae.13821. Epub 2019 Jul 29.

Rosemarie E. Venier, Lisa M. Maurer, Elena M. Kessler, Sarangarajan Ranganathan,  Richard L. McGough, Kurt R. Weiss, Marcus M. Malek, Julia Meade, Jean M. Tersak,  Kelly M. Bailey. A germline BARD1 mutation in a patient with Ewing Sarcoma: Implications for familial testing and counseling. Pediatric Blood & Cancer. Volume 66, Issue 9. First published: 03 June 2019.

Hey J Chong, Scott Maurer, Jennifer Heimall. What to Do with an Abnormal Newborn Screen for Severe Combined Immune Deficiency. Immunol Allergy Clin North Am. 2019 Nov;39(4):535-546. doi: 10.1016/j.iac.2019.07.007. Epub 2019 Aug 31.

Rosemarie E. Venier, Lisa M. Maurer, Elena M. Kessler, Sarangarajan Ranganathan,  Richard L. McGough, Kurt R. Weiss, Marcus M. Malek, Julia Meade, Jean M. Tersak,  Kelly M. Bailey. A germline BARD1 mutation in a patient with Ewing Sarcoma: Implications for familial testing and counseling. Pediatric Blood & Cancer. Volume 66, Issue 9. First published: 03 June 2019. 

J. Randall McAuley, Kelly M. Bailey, Prasanna Ekambaram, Linda R. Klei, Heejae Kang, Dong Hu, Tanner J. Freeman, Vincent J. Concel, Nathaniel E. Hubel, Jia-Ying (Lloyd) Lee, Hanna B. Klei, Jing Cheng, Preethiya Sekar, Rachel E. Bridwell, Lidija Covic, Peter C. Lucas & Linda M. McAllister-Lucas. MALT1 is a critical mediator of PAR1-driven NF-κB activation and metastasis in multiple tumor types. Oncogene volume 38, pages7384–7398(2019). Published: 16 August 2019.

Deirdre Nolfi-Donegan, Tirthadipa Pradhan-Sundd, Kirkwood A Pritchard Jr, Cheryl A Hillery. Redox Signaling in Sickle Cell Disease. Curr Opin Physiol. 2019 Jun;9:26-33. doi: 10.1016/j.cophys.2019.04.022. Epub 2019 May 2.

Weiqi Zhang, Jennifer Meyfeldt, Huabo Wang, Sucheta Kulkarni, Jie Lu, Jordan A Mandel, Brady Marburger, Ying Liu, Joanna E Gorka, Sarangarajan Ranganathan, Edward V Prochownik. β-Catenin mutations as determinants of hepatoblastoma phenotypes in mice. J Biol Chem. 2019 Nov 15;294(46):17524-17542. doi: 10.1074/jbc.RA119.009979. Epub 2019 Oct 9.

Allison G. Close MD,  Alexandra Dreyzin MD, MS,  Kimberly D. Miller MPH,  Brittani K.N. Seynnaeve MD, MS,  Louis B. Rapkin MD. Adolescent and young adult oncology—past, present, and future. CA Cancer J Clin. 2019 Nov;69(6):485-496. doi: 10.3322/caac.21585. Epub 2019 Oct 8.

Allison G. Close MD,  Alexandra Dreyzin MD, MS,  Kimberly D. Miller MPH,  Brittani K.N. Seynnaeve MD, MS,  Louis B. Rapkin MD. Adolescent and young adult oncology—past, present, and future. CA Cancer J Clin. 2019 Nov;69(6):485-496. doi: 10.3322/caac.21585. Epub 2019 Oct 8.

Kristin M Page, Elizabeth O Stenger, James A Connelly, David Shyr, Tara West, Susan Wood, Laura Case, Maureen Kester, Soo Shim, Lauren Hammond, Matthew Hammond, Christin Webb, Alessandra Biffi, Barbara Bambach, Ali Fatemi, Joanne Kurtzberg. Hematopoietic Stem Cell Transplantation to Treat Leukodystrophies: Clinical Practice Guidelines from the Hunter's Hope Leukodystrophy Care Network. Biol Blood Marrow Transplant. 2019 Dec;25(12):e363-e374. doi: 10.1016/j.bbmt.2019.09.003. Epub 2019 Sep 6.

Rebecca A Marsh, Jennifer W Leiding, Brent R Logan, Linda M Griffith, Danielle E Arnold, Elie Haddad, E Liana Falcone, Ziyan Yin, Kadam Patel, Erin Arbuckle, Jack J Bleesing, Kathleen E Sullivan, Jennifer Heimall, Lauri M Burroughs, Suzanne Skoda-Smith, Shanmuganathan Chandrakasan, Lolie C Yu, Benjamin R Oshrine, Geoffrey D E Cuvelier, Monica S Thakar, Karin Chen, Pierre Teira, Shalini Shenoy, Rachel Phelan, Lisa R Forbes, Deepak Chellapandian, Blachy J Dávila Saldaña, Ami J Shah, Katja G Weinacht, Avni Joshi, Farid Boulad, Troy C Quigg, Christopher C Dvorak, Debi Grossman, Troy Torgerson, Pamela Graham, Vinod Prasad, Alan Knutsen, Hey Chong, Holly Miller, M Teresa de la Morena, Kenneth DeSantes, Morton J Cowan, Luigi D Notarangelo, Donald B Kohn, Elizabeth Stenger, Sung-Yun Pai, John M Routes, Jennifer M Puck, Neena Kapoor, Michael A Pulsipher, Harry L Malech, Suhag Parikh, Elizabeth M Kang, submitted on behalf of the Primary Immune Deficiency Treatment Consortium. Chronic Granulomatous Disease-Associated IBD Resolves and Does Not Adversely Impact Survival Following Allogeneic HCT. J Clin Immunol. 2019 Oct;39(7):653-667. doi: 10.1007/s10875-019-00659-8. Epub 2019 Aug 2.

Elizabeth O Stenger, Shalini Shenoy, Lakshmanan Krishnamurti. How I treat sickle cell disease with hematopoietic cell transplantation. Blood. 2019 Dec 19;134(25):2249-2260. doi: 10.1182/blood.2019000821.

Alexandra Dreyzin, Marian G Michaels, Mark T Vander Lugt, Paul Szabolcs. Oral ribavirin for paramyxovirus infection after alemtuzumab-containing reduced-intensity conditioning HCT regimen. Pediatr Transplant. 2019 Mar;23(2):e13358. doi: 10.1111/petr.13358. Epub 2019 Jan 27.

Andrew C Dietz, Kristy Seidel, Wendy M Leisenring, Daniel A Mulrooney, Jean M Tersak, Richard D Glick, Cathy A Burnweit, Daniel M Green, Lisa R Diller, Susan A Smith, Rebecca M Howell, Marilyn Stovall, Gregory T Armstrong, Kevin C Oeffinger, Leslie L Robison, Amanda M Termuhlen. Solid organ transplantation after treatment for childhood cancer: a retrospective cohort analysis from the Childhood Cancer Survivor Study. Lancet Oncol. 2019 Oct;20(10):1420-1431. doi: 10.1016/S1470-2045(19)30418-8. Epub 2019 Aug 27.

Rosemarie E. Venier, Lisa M. Maurer, Elena M. Kessler, Sarangarajan Ranganathan,  Richard L. McGough, Kurt R. Weiss, Marcus M. Malek, Julia Meade, Jean M. Tersak,  Kelly M. Bailey. A germline BARD1 mutation in a patient with Ewing Sarcoma: Implications for familial testing and counseling. Pediatric Blood & Cancer. Volume 66, Issue 9. First published: 03 June 2019. 

Patrick T. Ebbert,  Frederico Xavier,  Craig D. Seaman,  Margaret V. Ragni. Emicizumab prophylaxis in patients with haemophilia A with and without inhibitors. Haemophilia. 2020 Jan;26(1):41-46. doi: 10.1111/hae.13877. Epub 2019 Nov 20.

Jillian Lapinski, Lisa M Maurer, Margaret V Ragni, Cheryl McShea, James D Cooper, Frederico Xavier. Unsuspected Lyme disease presenting in refractory haemophilic haemarthrosis. Haemophilia. 2019 Sep;25(5):e331-e333. doi: 10.1111/hae.13821. Epub 2019 Jul 29.

2018 

Upadhyaya SA, Broniscer A. Chemotherapy of Pediatric High-Grade Gliomas. In: Newton HB, ed. Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition. San Diego: Academic Press, 2018: pp-pp. 557-568 

Broniscer A, Nichols K. Predisposition Syndromes to Central Nervous System Cancers. Brain Tumors in Children. Ed. Amar Gajjar, Frank Smith, Judy Racadio, and Greg Reaman. Springer, 2018: pp-pp.91-116 

Pollack IF, Agnihotri S, Broniscer A. Childhood brain tumors: current management, biological insights and future directions. J Neurosurg in press 

Pinto EM, Hamideh D, Bahrami A, Orr BA, Lin T, Pounds S, Zambetti GP, Pappo AS, Gajjar A, Agnihotri S, Broniscer A. Malignant rhabdoid tumors originating within and outside the central nervous system are clinically and molecularly heterogeneous. Acta Neuropathol 136:315-326, 2018 

Broniscer A, Jia S, Mandrell B, Hamideh D, Huang J, Onar-Thomas A, Gajjar A, Raimondi SC, Tatevossian RG, Stewart CF. Phase 1 trial, pharmacokinetics, and pharmacodynamics of dasatinib combined with crizotinib in children with recurrent or progressive high-grade and diffuse intrinsic pontine glioma. Pediatr Blood Cancer in pres 

Upadhyaya SA, R McGee, Wilky B, Broniscer A. Malignant progression of a peripheral nerve sheath tumor in the setting of rhabdoid tumor predisposition syndrome. Pediatr Blood Cancer in press 

Hoffman LM, Veldhuijzen van Zanten SEM, Colditz N, Baugh J, Chaney B, Hoffmann M, Lane A, Fuller C, Miles L, Hawkins C, Bartels U, Bouffet E, Goldman S, Leary S, Foreman NK, Packer R, Warren KE, Broniscer A, Kieran MW, Minturn J, Comito M, Broxson E, Shih CS, Khatua S, Chintagumpala M, Carret AS, Escorza NY, Hassall T, Ziegler DS, Gottardo N, Dholaria H, Doughman R, Benesch M, Drissi R, Nazarian J, Jabado N, Boddaert N, Varlet P, Giraud G, Castel D, Puget S, Jones C, Hulleman E, Modena P, Giagnacovo M, Antonelli M, Pietsch T, Gielen GH, Jones DTW, Sturm D, Pfister SM, Gerber NU, Grotzer MA, Pfaff E, von Bueren AO, Hargrave D, Solanki GA, Jadrijevic Cvrlje F, Kaspers GJL, Vandertop WP, Grill J, Bailey S, Biassoni V, Massimino M, Calmon R, Sanchez E, Bison B, Warmuth-Metz M, Leach J, Jones B, van Vuurden DG, Kramm CM, Fouladi M. Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG): a collaborative report from the International and European Society for Pediatric Oncology DIPG registries. J Clin Oncol 36:1963-1972, 2018 

Tinkle C, Duncan E, Doubrovin M, Han Y, Li Y, Kim H, Broniscer A, Snyder SE, Merchant TE, Shulkin B. Evaluation of 11C-methionine PET and anatomic MRI associations in diffuse intrinsic pontine glioma. J Nucl Med in press 

Stanley K, Cooper J. Hormone Therapy and Venous Thromboembolism in a Transgender Adolescent. J Pediatric Hematol Oncol 2018 Jan, 40 (1) :e38-e40. PubMed PMID 28945660 

McCormick MC, Siripong N, Cooper JD. Desmopressin stimulation testing: Response to intravenous and intranasal forms. Haemophilia. 2018 mar 26. ePub ahead of print. PubMed PMID 29578274 

Ekambaram P, Lee JL, Hubel NE, Hu D, Yemeni S, Campbell PG, Pollock N, Klei LR, Concel VJ, Delekta PC, Chinnaiyan AM, Tomlins SA, Rhodes DR, Priedigkeit N, Lee AV, Oesterreich S, McAllister-Lucas LM*, Lucas PC*. The CARMA3-Bcl10-MALT1 signalosome drives NF-kB activation and promotes aggressiveness in Angiotensin II Receptor-Postive Breast Cancer (2018) Cancer Res, 78:1225-1240. * these authors share senior authorship   

McAuley JR, Freeman T, Ekambaram P, Lucas PC, McAllister-Lucas LM.  CARMA3 is a critical mediator of GPCR and RTK-driven solid tumor pathogenesis (2018) Frontiers in Immunology, in press 

Benneh-Akwasi Kuma A, Owusu-Ansah AT, Ampomah MA, Sey F, Olayemi E. Nouraie M, Ofori-Acquah SF. Prevalence of relative systemic hypertension in adults with sickle cell disease in Ghana. PLoS Once 2018 Jan 4;13(1):30190347. doi.10.1371/ journal.pone.0190347. eCollections 2018 

Dolezal JM, Dash AP, Prochownik EV. Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers. BMC Cancer. 2018 Mar 12;18(1):275 

Wang H, Dolezal JN,'I, Kulkarni S, Lu J, Mandel J, Alencastro F, Duncan AW, Prochownik EV Myc and ChREBP cooperatively regulate normal and neoplastic hepatocyte proliferation. J. Biol. Chem. 2018.293: 14740-14757 

Gil L, Zhu Y, Lin X, Li Y, Cui K, Prochownik EV, Li Y. Amplification of glyceronephosphate O-acyltransferase and recruitment ofUSP30 stabilize DRPI to promote hepatocarcinogenesis. Cancer Res. 20 18.78:5808-5819. 

Goetzman ES, Prochownik FN. The role fòr myc in coordinating glycolysis, oxidative phosphorylation, glutaminolysis, and fatty acid metabolism in normal and neoplastic tissues. Front Endocrinol (Lausanne). 2018 Apr 12;9: 129. 

Wang H, Lu J, Kulkarni S, Gorka J, Mandel J, Goetzman ES, Prochownik EV. Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation (submitted for publication). 

Mandel J, Wang I-I. Normolle IDP, Lucas PC, Benos P, Prochownik EV. Prediction of longterm survival in cancer patients based on expression patterns of 212 or fewer protein-coding transcripts (submitted for publication) 

Wang H, Lu J, Dolezal JM, Kulkarni S, Zhang W, Chen A, Gorka J, Mandel J, Prochownik EV. Inhibition of hepatocellular carcinoma by metabolic normalization (submitted for publication). 

Zhang, Q, Li X, Cui K Prochownik EV, Li Y. The MAP3K13-TRlM25-FBXW7Œ axis affects c-Myc protein stability and tumor progression (submitted for publication). 

2017

Leeper CM, Vissa M, Cooper JD, Malec LM, Gaines BA. Venous thromboembolism in pediatric trauma patients: Ten-year experience and long-term follow-up in a tertiary care center. Pediatr Blood Cancer. 2017;64(8).

Cooper JD, Costello AG, Shaw PH. A comparison of extremity thrombosis rates in adolescent and young adult versus younger pediatric oncology patients at a children’s hospital. J Adolesc Young Adult Oncol. 2017;6(1):62-6.

O’Halloran K, Ritchey AK, Djokic M, Friehling E. Transient juvenile myelomonocytic leukemia in the setting of PTPN11 mutation and Noonan syndrome with secondary development of monosomy 7. Pediatr Blood Cancer. 2017;64(7).

Ou Z, Sherer M, Casey J, Bakos HA, Vitullo K, Hu J, Friehling E, et al. The genomic landscape of PAX5, IKZF1, and CDKN2A/B alterations in B-cell precursor acute lymphoblastic leukemia. Cytogenet Genome Res. 2016;150(3-4):242-52.

Panepinto JA, Paul Scott J, Badaki-Makun O, Darbari DS, Chumpitazi CE, Airewele GE, Ellison AM, Smith-Whitley K, Mahajan P, Sarnaik SA, Charles Casper T, Cook LJ, Leonard J, Hulbert ML, Powell EC, Liem RI, Hickey R, Krishnamurti L, Hillery CA, Brousseau DC; Pediatric Emergency Care Applied Research Network (PECARN). Determining the longitudinal validity and meaningful differences in HRQL of the PedsQLTM Sickle Cell Disease Module. Health Qual Life Outcomes. 2017;15(1):124.

Larson MC, Kara n MS, Hillery CA, Hogg N. Phosphatidylethanolamine is progressively exposed in RBCs during storage. Transfus Med. 2017;27(2):136-41.

Thrane SE, Maurer SH, Cohen SM, May C, Sereika SM. Pediatric palliative care: A five-year retrospective chart review study. J Palliat Med. 2017;20(10):1104-11.

Ivanov AA, Gonzalez-Pecchi V, Khuri LF, Niu Q, Wang Y, Xu U, Bai Y, Mo X Prochownik EV, et al. OncoPPi- informed discovery of mitogen-activated protein kinase 3 as a novel binding partner of c-Myc. Oncogene. 2017. Epub ahead of print.

Zhang Y, Bharathi SS, Rardin MJ, Lu J, Maringer KV, Sims-Lucas S, Prochownik EV, et al. Lysine desuccinylase SIRT5 binds to cardiolipin and regulates the electron transport chain. J Biol Chem. 2017;292(24):10239-49.

Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV. Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma. J Biol Chem. 2017;292(24):10068-86.

Landier W, Hageman L, Chen Y, Kornegay N, Evans WE, Bostrom BC, Casillas J, Dickens DS, Angiolillo AL, Lew G, Maloney KW, Mascarenhas L, Ritchey AK, et al. Mercaptopurine ingestion habits, red cell thioguanine nucleotide levels, and relapse risk in children with acute lymphoblastic leukemia: A report from the Children’s Oncology Group study AALL03N1. J Clin Oncol. 2017;35(15):1730-6.

Landier W, Chen Y, Hageman L, Kim H, Bostrom BC, Casillas JN, Dickens DS, Evans WE, Maloney KW, Mascarenhas  L, Ritchey AK, et al. Comparison of self-report and electronic monitoring of 6MP intake in childhood ALL: A Children’s Oncology Group study. Blood. 2017;129(14):1919-26.

Makadia P, Srinath A, Madan-Khetarpal S, McGuire M, Infante E, Zhang J, Felgar RE, Davis AW, Chong HJ, Windreich RM. Aplastic anemia and cytotoxic T lymphocyte antigen-4 haploinsufficiency treated with bone marrow transplantation. J Allergy Clin Immunol Pract. 2017;5(5):1445-7.e2.

Cooper JD, Ritchey AK. Response to treatment and adverse events associated with use of recombinant activated factor VII in children: A retrospective cohort study. Ther Adv Drug Saf. 2017;8(2):51-9.

Goyal RK, Ibrahimova A, Escolar ML, Szabolcs P, Lugt MV, Windreich RM, Weiner DJ. Forced deflation pulmonary function test: A novel method to evaluate lung function in infants and young children. Pediatr Blood Cancer. 2017;64(4).

Proud L, Ritchey AK. Management of type 2b von Willebrand disease in the neonatal period. Pediatr Blood Cancer. 2017;64(1):103-5.

Wang X, Sun CL, Hageman L, Smith K, Singh P, Desai S, Hawkins DS, Hudson MM, Mascarenhas L, Neglia JP, Oeffinger KC, Ritchey AK, Robison LL, Villaluna D, Landier W, Bhatia S. Clinical and genetic risk prediction of subsequent CNS tumors in survivors of childhood cancer: A report from the COG ALTE03N1 study. J Clin Oncol. 2017;35(32):3688-96.

Oparaji JA, Rose F, Okafor D, Howard A, Turner RL, Orabi AI, Byersdorfer C, Mi Q, Ritchey K, Lowe ME, Husain SZ. Risk factors for asparaginase-associated pancreatitis: A systematic review. J Clin Gastroenterol. 2017;51(10):907-13.

2016

Windreich RM, Goyal RK, Joshi R, Kenkre TS, Howrie D, Venkataramanan R. A pilot study of continuous infusion of mycophenolate mofetil for prophylaxis of graft-versus-host disease in pediatric patients. Biol Blood Marrow Transplant. 2016;22(4):682-9.

Boiko JR, Srinath AI, Cooper JD. Portomesenteric venous thrombosis in previously healthy adolescents presenting with subacute abdominal pain. Clin Pediatr. 2016;55(10):975-8.

Owusu-Ansah A, Ihunnah CA, Walker AL, Ofori-Acquah SF. Inflammatory targets of therapy in sickle cell disease. Transl Res. 2016;167(1):281-97.

Tubergen DG, Friehling E, Bleyer A, Ritchey AK. Cancer and benign tumors: the leukemias; acute lymphoblastic leukemia; acute myelogenous leukemia; Down syndrome and acute leukemia and transient myeloproliferative disorder; chronic myelogenous leukemia; juvenile myelomonocytic leukemia; infant leukemia. In: Kligman RM, Behrman RE, Stanton BF, Schor N, St. Geme J, eds. Nelson Textbook of Pediatrics. 20th ed. New York, NY: Elsevier; 2016.

Wandersee NJ, Hillery CA. Red blood cells and the vaso-occlusive process. In: FF Costa, N Conran, eds., Sickle Cell Anemia: From Basic Science to Clinical Practice. Springer; 2016. Barnett M, Maurer S, Wood, G. Pediatric palliative care pilot curriculum: Impact of “pain cards” on resident education. Am J Hosp Palliat Care. 2016;33(9):829-33.

Kelly J, May C, Maurer S. Assessment of the spiritual needs of primary caregivers of children with life-limiting illnesses is valuable yet inconsistently performed in the hospital. J Palliat Med. 2016;19(7):763-6.

Thrane S, Maurer S, Ren D, Danford C, Cohen S. Reiki therapy for symptom management in children receiving palliative care: A pilot study. Am J Hosp Palliat Care. 2016. Epub ahead of print.

Ghosh S, Ihunnah CA, Hazra R, Walker AL, Hansen JM, Archer DR, Owusu-Ansah AT, Ofori-Acquah SF. Nonhematopoietic Nrf2 impedes adult progression of sickle cell anemia in mice. JCI Insight. 2016;1(4). pii: e81090.

Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Stolz DB, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV. Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in hepatoblastoma. J Biol Chem. 2016;291(51):26241-26251.

Edmunds LR, Otero PA, Sharma L, D’Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck
ME, Vockley J, Monga SP, Kershaw EE, O’Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV. Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes. Oncotarget. 2016;7(21):30379-95.

Han H, Chen Y, Cheng L, Prochownik EV, Li Y. MicroRNA-206 impairs c- Myc-driven cancer in a synthetic lethal manner by directly inhibiting MAP3K13. Oncotarget. 2016;7(13):16409-19.

Li Y, Zhu Y, Prochownik EV. MicroRNA- based screens for synthetic lethal interactions with c-Myc. RNA Dis. 2016;3(3). pii: e1330.

Wigton JC, Tersak JM. JAK2+ essential thrombocythemia in a young girl with Budd-Chiara syndrome: Diagnostic and therapeutic considerations when adult disease strikes the young. J Pediat Hematol Oncol. 2016;38(1):70-3.

Vrooman LM, Kirov II, Dreyer ZE, Kelly M, Hijiya N, Brown P, Drachtman RA, Messinger YH, Ritchey AK, et al. Activity and toxicity of intravenous Erwinia asparaginase following allergy to E. coli-derived asparaginase in children and adolescents with acute lymphoblastic leukemia. Pediatr Blood Cancer. 2016;63(2):228-33.

Rosebeck S, Elenitoba-Johnson KSJ, Lim MS, *McAllister-Lucas LM, *Lucas PC. The API2-MALT1 fusion oncoprotein directs a unique program of substrate ubiquitination and proteolysis to promote lymphomagenesis. World J Biol Chem. 2016;7(1):128-37. *co-senior authors.

Ragni MV, DiMichele DM, Hay CM, Malec LM, Seaman CD, Li J, et al. Thrombin generation and bleeding in haemophillia inhibitor patients during immune tolerance induction. Haemophillia. 2016;22(2):240-7.

Malec LM, Moore CG, Bennett CM, Yee DL, Kerlin BA, Witmer CM, et al. Validation study of the composite score to identify von Willebrand disease in children. J Pediatr Hematol Oncol. 2016;38(2):139-42.

Klei LR, Hu D, Panek R, Alfano DN, Bridwell RE, Bailey KM, Oravecz- Wilson KI, Concel VJ, Hess EM, Van Beek M, Delekta PC, Gu S, Watkins SC, Ting AT, Gough PJ, Foley KP, Bertin J, McAllister-Lucas LM, Lucas PC. MALT1 protease activation triggers acute disruption of endothelial barrier integrity via CYLD cleavage. Cell Rep. 2016;17(1):221-32.

Bailey KM, Airik M, Krook MA, Pedersen EA, Lawlor ER. Micro-environmental stress induces src-dependent activation of invadopodia and cell migration in Ewing sarcoma. Neoplasia. 2016;18(8):480-8.

Chang W, Brohl AS, Patidar R, Sindiri S, Shern JF, Wei JS, et al. Multidimensional ClinOmics for precision therapy of children and adolescent young adults with relapsed and refractory cancer: A report from the Center for Cancer Research. Clinical Cancer Research. 2016; 22(15):3810-20.

Bertero A, Pawlowski M, Ortmann D, Snijders K, Yiangou L, Cardoso de Brito M, Brown S, Bernard WG, Cooper JD, et al. Optimized inducible shRNA and CRISPR/Cas9 platforms for in vitro studies of human development using hPSCs. Development. 2016;143(23):4405-18.

Brandow AM, Wandersee NJ, Dasgupta M, Hoffmann RG, Hillery CA, Stucky CL, Panepinto JA. Substance P is increased in patients with sickle cell disease and associated with haemolysis and hydroxycarbamide use. Br J Haematol. 2016;175(2):237-45.

Kazmerski TM, Weiner DJ, Matisko J, Schachner D, Lerch W, May C, Maurer SH. Advance care planning in adolescents with cystic brosis: A quality improvement project. Pediatr Pulmonol. 2016;51(12): 1304-10

2015

Nie Z, Du MQ, McAllister-Lucas LM, Lucas PC, Bailey NG, Hogaboam CM, Lim MS, Elenitoba-Johnson KS. Conversion of the LIMA1 tumor suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma. Nature Communications. 2015;6:5908.

Bhatia S, Landier W, Hageman L, Heeyoung K, Yanjun C, Sun C-L, Kronegay N, Evans WE, Angiolillo AL, Bostrom B, Casillas J, Lew G, Maloney KW, Mascarenhas L, Meza J, Ritchey AK, Termuhlen AM, Carroll, WL, Wong FL, Relling MV. Systemic exposure to thiopurines and risk of relapse. JAMA Oncology. 2015;1(3):287-95.

Ozolek JA, Cohen D, Kool M, Pfister SM, Korshunov A, Bukowinski AJ, Davis AW. Medulloepithelioma with a peculiar clinical presentation, stem cell phenotype, and aberrant DNA-methylation profile. CNS Oncol. 2015;4(4);203-12.

Bukowinski AJ, Burns KC, Parsons K, Perentesis JP, O’Brien MM. Toxicity of cancer therapy in adolescents and young adults. Semin Oncol Nurs. 2015;31(3):216-26.

Buryk MA, Picarsic JL, Creary SE, Shaw PH, Simons JP, Deutsch M, Monaco SE, Nikiforov YE, Witchel SF. Identi cation of unique, heterozygous germline mutation, STK11 (p. F354L), in a child with an encapsulated follicular variant of papillary thyroid carcinoma within six months of completing treatment for neuroblastoma. Pediatr Dev Pathol. 2015;18(4):318-23.

Shaw PH, Reed DR, Yeager N, Zebrack B, Castellino SM, Bleyer A. Adolescent and young adult oncology in the United States: A specialty in its late adolescence. J Pediatr Hematol Oncol. 2015;37(3):161-9.

Raja M, Zverev M, Seipel K, Williams GT, Clarke AR, Shaw PH. Assessment of the in vivo activity of P13K and MEK inhibitors in genetically de ned models of colorectal cancer. Mol Cancer Ther. 2015;14(10):2175-86.

Malec LM, Moore CG, Yabes J, LiJ, Ragni MV. Postpartum haemorrage in women with von Willebrand disease:
An observational study of the Pennsyl- vania Health Care Cost Containment Council (PHC4) database. Haemophillia. 2015;21(5):e442-5.

Ilechie AA, Abokyi S, Owusu-Ansah A, Boadi-Kusi SB, Denkyira AK, Abraham CH. Self-refraction accuracy with adjustable spectacles among children in Ghana. Optom Vis Sci. 2015;92(4):456-63.

Schiff M, Haberberger B, Xia C, Mohsen AW, Goetzman ES, Wang Y, Uppala R, Zhang Y, Karunanidhi A, Prabhu D, Alhardbi H, Prochownik EV, Haack T, Haberle J, Munnich A, Rotig A, Taylor RW, Nichools RD, Kim JJ, Prokisch H, Vockley J. Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency. Hum Mol Genet. 2015;24(11):3238-47.

Jung KY, Wang H, Teriete P, Yap JL, Chen L, Lanning ME, Hu A, Lambert LJ, Holien T, Sundan A, Cosford ND, Prochownik EV, Fletcher S. Perturbation of the c-Myc-Max protein-protein interaction via synthetic a-helix mimetics. J Med Chem. 2015;58(7):3002-24.

Soodgupta D, Pan D, Cui G, Senpan A, Yang Z, Lu L, Weilbaecher KN, Prochownik EV, Lanza GM, Tomasson MH. Small molecule MYC inhibitor conjugated to Intergrin-targeted nanoparticles extends survival in a mouse model of disseminated multiple myeloma. Mol Cancer Ther. 2015;14(6):1286-94.

Wang H, Sharma L, Lu J, Finch P, Fletcher S, Prochownik EV. Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion. Oncotarget. 2015;6(18):15857-70.

Edmunds LR, Sharma L, Wang H, Kang A, D’Souza S, Lu J, McLaughlin M, Dolezal JM, Gao X, Weintraub ST, Ding Y, Zeng X, Yates N, Prochownik EV. C-Myc and AMPK control cellular energy levels by cooperatively regulating mitochondrial structure and function. PLOS ONE. 2015;10(7):e0134049.

Edmunds LR, Sharma L, Kang A, Lu J, Vockley J, Basu S, Uppala R, Goetzman ES, Beck ME, Scott D, Prochownik EV. c-Myc programs fatty acid metabolism and dictates acetyl-CoA abundance and fate. J Biol Chem. 2015;290(33):20100.

Wang H, Ramakrishnan A, Fletcher S, Prochownik EV. A quantitative, surface plasmon resonance-based approach to evaluating DNA binding by the c-Myc oncoprotein and its disruption by small molecule inhibitors. J Biol Methods. 2015;2(2). pii: e18.

Wang H, Teriete P, Hu A, Raveendra-Panickar D, Pendelton K, Lazo JS, Eiseman J, Hollen T, Misund K, Oliynyk G, Arsenian-Henriksson M, Cosford ND, Sundan A, Prochownik EV. Direct inhibition of c-Myc Max heterodimers by celastrol and celastrol-inspired triterpenoids. Oncotarget. 2015;6(32):32380-95.

Ho CY, Mobley BC, Gordish-Dressman H, VandenBussche CJ, Mason GE, Bornhorst M, Esbenshade AJ, Tehrani M, Orr BA, LaFrance DR, Devaney JM, Letzer BW, Hofherr SE, Burger PC, Packer RJ.A clinicopathologic study of diencephalic pediatric low-grade gliomas with BRAF V600 mutation. Acta Neuropathol. 2015;130(4):575-85.

Ataga KI, Hinderliter A, Brittain JE, Jones S, Xu H, Cai J, Kim S, Pritchard KA, Hillery CA. Association of pro-inflammatory high-density lipoprotein cholesterol with clinical and laboratory variables in sickle cell disease. Hematology. 2015;20(5):289-96.

Brousseau DC, Scott JP, Badaki-Makun O, Darbari DS, Chumpitazi CE, Airewele GE, Ellison AM, Smith-Whitley K, Mahajan P, Sarnaik SA, Casper TC, Cook LJ, Dean JM, Leonard J, Hulbert ML, Powell EC, Liem RI, Hickey R, Krishnamurti L, Hillery CA, Nimmer M, Panepinto JA. Pediatric Emergency Care Applied Research Network (PECARN). A multicenter randomized controlled trial of intravenous magnesium for sickle cell pain crisis in children. Blood. 2015;126(14):16517.

Yan X, Yan M, Guo Y, Singh G, Chen Y, Yu M, Wang D, Hillery CA, Chan AM. R-Ras regulates murine T cell migration and intercellular adhesion molecule-1 binding. PLoS.One. 2015;10(12):e0145218.

Taylor M, Jakacki R, May C, Howrie D, Maurer S. Ketamine PCA for treatment of end-of-life neuropathic pain in pediatrics. Am J Hosp Palliat Care. 2015;32(8):841:8.

Owusu-Ansah A, Choi SH, Petrosiute A, Letterio JJ, Huang A. Triterpenoid inducers of Nrf2 signaling as potential therapeutic agents in sickle cell disease – a review. Front Med. 2015;9(1):46-56.

Wang H, Teriete P, Hu A, Raveendra- Panickar D, Pendelton K, Lazo JS, Eiseman J, Holien T, Misund K, Oliynyk G, Arsenian-Henriksson M, Cosford ND, Sundan A, Prochownik EV. Direct inhibition of c-Myc-Max heterodimers by celastrol and celastrol-inspired triterpenoids. Oncotarget. 2015;6(32):32380-95.

Ozolek JA, Cohen DE, Kool M, Pfister SM, Korshunov A, Bukowinski AJ, Davis AW. Medulloepithelioma with peculiar clinical presentation, stem cell phenotype, and aberrant DNA methylation profile. CNS Oncology. 2015;4(4):203-12.