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- Adolescent and Young Adult Medicine
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- Blood and Marrow Transplantation and Cellular Therapies
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- Neurology and Child Development
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- Paul C. Gaffney Division of Pediatric Hospital Medicine
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- Center for Pediatric Research in Obesity and Metabolism
- Center for Rare Disease Therapy
- Children's Neuroscience Institute
- Cystic Fibrosis Research Center
- Institute for Infection, Inflammation, and Immunity in Children
- Pediatric Asthma Center
- Pediatric Institute for Heart Regeneration and Therapeutics
- Richard King Mellon Foundation Institute for Pediatric Research
- Pittsburgh Vaccine Trials Unit
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Research
Basic Science
Our division uses varied methods to explore the following areas:
- Elucidating the mechanisms of neurodegenerative disease using mouse, fly, worm and induced pluripotent stem cells (IPSC) models
- Evaluating the effects of prenatal exposure to glucocorticoids and cannabinoids on brain development
- Using viral oncotherapy to generate anti-tumor memory T-cells
- Combining fMRI and quantitative electroencephalogram (qEEG) processing data to determine brain re-organization and neural plasticity following injury in children
Lead Researchers
- Udai Pandey, PhD
- Samuel Todd Lamitina, PhD
- Alexis L. Franks, MD
- Christina M. Patterson, MD
- Ira Bergman, MD, PhD
Collaborators
Clinical Research
The clinical faculty have a broad range of research interests:
- Developing qEEG and statistical machine-learning methods that deeply interrogate continuous EEG data and automatically warn of ongoing neurologic deterioration
- Elucidating the genetic contributions to infantile-onset epilepsy
- Evaluating clinical genetic therapies of neuromuscular disorders
- Studying drug therapies that modify language learning in young children with Fragile X syndrome
- Clinically characterizing a new neurogenetic disorder caused by mutations in the GEMIN5 gene
- Studying the natural history and neuro-radiological manifestations of childhood neuro-immunological diseases
- Serving as the regional coordinating center of the Stroke Trials Network
Collaborators
- Christopher Genovese, PhD
- Mark Scheuer, MD
- Persyst Corporation
- NeuroNext
Quality Improvement (QI)
Several quality improvement projects have been initiated by the division, including studying reproductive healthcare in women with epilepsy and developing QI methodology that reduces hospital admissions for neurological disease. These projects are conducted in collaboration with Traci Marie Kazmerski, MD, MS of the Division of Adolescent and Young Adult Medicine.