Work from our lab extends to other autoimmune diseases, and collaborations with multiple groups, both inside and outside the University of Michigan. These include epigenomic studies in scleroderma in collaboration with the Scleroderma Program at the University of Michigan, primary Sjögren’s syndrome in collaboration with OMRF in Oklahoma, giant cell arteritis in collaboration with the Department of Ophthalmology and the School of Public Health at the University of Michigan, lupus neutrophils and low density granulocytes in collaboration with the NIH, genomic studies in giant cell arteritis in collaborations with centers in Spain and the UK, genomic studies in myasthenia gravis in collaboration with Istanbul University in Turkey, and other collaborative projects that are in the early phases of planning and execution, including exploring the microbiome in patients with Behçet’s disease and how it might be influenced by genetic risk in this disease.
Immunohistochemistry staining to confirm "epigentic immunophenotyping" results in giant cell arteritis (Source: Coit et al. Annals of the Rheumatic Diseases 2015)
Barchart of bacterial relative abundances colored by bacterial genus in Behçet’s disease patients (blue box) and healthy controls (red box)
(Source: Coit et al. Clinical Immunology 2016.)