Recent Publications

2018 

Eddens T, Kaplan DJ, Anderson AJM, Nowalk AJ, Campfield BT*.  Insights from the Geographic Spread of the Lyme Disease Epidemic.  Clin Infect Dis. Epub 2018 Jun 16 doi:10.1093/cid/ciy510 PMID: 29920580 PMCID: pending 

Lopez SMC, Campfield BT, Nowalk AJ.  J Pediatric Infect Dis Soc. Epub 2018 Aug 28.  Doi:10.1093jpids/piy072 PMID: 30169816 

Dumont TF, Mouillet JF, Bayer A, Gardner CL, Klimstra WK, Wolf DG, Yagel S, Balmir F, Binstock A, Sanfilippo JS, Coyne CB*, and Sadovsky Y*. The expression level of C19MC miRNAs in early pregnancy and in response to viral infection. Placenta, May;53:23-29. PMID: 28487016. (*co-corresponding).  

Bayer A, Lennemann NJ, Ouyang Y, Sadovsky E, Sheridan MA, Roberts MR, Coyne CB*, Sadovsky Y*. Chromosome 19 microRNAs exert antiviral activity independent from type III interferon signaling. Placenta 2018 Jan; 61:33-38 PMID: 29277269. (*co-corresponding).  

Yockey LJ, Jurado KA, Arora N, Millet A, Rakib T, Milano KM, Hastings AK, Fikrig E, Kong Y, Horvath TL, Weatherbee S, Kliman HJ, Coyne CB, Iwasaki A. Type I interferons instigate fetal demise after Zika virus infection. Science Immunology 2018 Jan 5;3(19) PMID: 29305462.  

Ander SE, Rudzki EN, Arora N, Sadovsky Y, Coyne CB*, Boyle JP*. Human Placental Syncytiotrophoblasts Restrict Toxoplasma gondii Attachment and Replication and Respond to Infection by Producing Immunomodulatory Chemokines. mBio 2018 Jan 9;9(1). PMID: 29317509. (*co-corresponding).  

Platt DJ, Smith AM, Arora N, Diamond MS, Coyne CB, and Miner JJ. Zika virus-related neurotropic flaviviruses infect human mid-gestation placental explants and cause fetal demise in mice. 2017 Science Translational Medicine 2018 Jan 31;10(426). PMID: 29386359.  

Delorme-Axford E, Abernathy E, Lennemann NJ, Bernard A, Ariosa A, Backues S, Coyne CB, Kirkegaard K, and Klionsky D. The Exoribonuclease Xrn1 Is a Post-Transcriptional Negative Regulator of Autophagy. Autophagy 2018 Mar 21:1-15. PMID: 29465287 

Wells, AI and Coyne, CB. Type III Interferons in Antiviral Defenses at Barrier Surfaces.  Trends Immunol, 2018 Sep; doi: 10.1016/j/it/2018.08.008.PMID: 30219309 

Corry J, Bergelson JM, Coyne CB. Enterovirus Receptors and Entry. In: Jackson WT, Coyne CB, editors. Enteroviruses: Omics, Molecular Biology, and Control. First edition ed: Caister Academic Press 2018. p. 7-22.  

Lanik WE, Mara MA, Mihi B, Coyne CB, Good M. Stem Cell-Derived Models of Viral Infections in the Gastrointestinal Tract. Viruses. 2018;10(3). Epub 2018/03/15. doi: 10.3390/v10030124. PubMed PMID: 29534451; PMCID: PMC5869517.  

Knowlton, J. J., Fernández de Castro, I., Ashbrook, A. W., Gestaut, D. R., Zamora, P. F., Bauer, J. A., Forrest, J. C., Frydman, J., Risco, C., and T. S. Dermody. The TRiC chaperonin controls reovirus replication through outer-capsid folding. Nat. Microbiol. 3:481-493, 2018. PMCID: PMC5874176 [Featured in Nature Microbiology News and Views] 

Brown, J. J., Short, S. P., Stencel-Baerenwald, J. E., Urbanek, K., Pruijssers, A. J., McAllister, N., Ikizler, M., Taylor, G., Aravamudhan, P., Khomandiak, S., Jabri, B., Williams, C. S., and T. S. Dermody. Reovirus-induced apoptosis in the intestine limits establishment of enteric infection. J. Virol92:e02062-17, 2018. PMCID: PMC5923068 [Cover illustration] 

Wu, A. G., Pruijssers, A. J., Brown, J. J., Stencel-Baerenwald, J. E., Sutherland, D. M., Iskarpatyoti, J. A., and T. S. Dermody. Age-dependent susceptibility to reovirus encephalitis in mice is influenced by maturation of the type-I interferon response. Pediatr. Res83:1057-1066, 2018. PMCID: PMC5959747 

Dietrich, M. H., Ogden, K. M., Long, J. M., Ebenhoch, R., Thor, A., Dermody, T. S., and T. Stehle. Structural and functional features of the reovirus s1 tail. J. Virol. 92:e00336-18, 2018. PMCID: PMC6026731 [Cover illustration] 

Zamora, P. F., Hu, L., Knowlton, J. J., Lahr, R. M., Moreno, R. A., Berman, A. J., Prasad, B. V. V., and T. S. Dermody. Reovirus nonstructural protein sNS acts as an RNA stability factor promoting viral genome replication. J. Virol. 92:e00563-18, 2018. PMCID: In progress 

Gopal, S., Perez, Jr., E., Xia, A., Knowlton, J. J., Cerqueira, F., Dermody, T. S., and J. W. Upton. Murine cytomegalovirus M72 promotes acute virus replication in the natural host and is a substrate of the TRiC/CCT complex. Virology 522:92-105, 2018. PMCID: In progress 

Tenorio, R., Fernández de Castro, I., Knowlton, J. J., Zamora, P. F., Lee, C. H., Mainou, B. A., Dermody, T. S., and C. Risco. Reovirus sNS and mNS proteins remodel the endoplasmic reticulum to build replication neoorganelles. mBio. In press. PMCID: In progress 

Sutherland, D. M., Aravamudhan, P., Dietrich, M. H., Stehle, T., and T. S. Dermody. Reovirus neurotropism and virulence are dictated by sequences in the head domain of the viral attachment protein. J. Virol. In press. PMCID: In progress 

Bouziat, R., Biering, S. B., Hinterleitner, R., Kouame, E., Sangani, K. A., Ernest, J. D., Varma, M., Brown, J. J., Urbanek, K., Dermody, T. S., Ng, A., Hwang, S., and B. Jabri. Norovirus infection induces inflammatory responses to dietary antigens. Cell Host Microbe. Accepted for publication with revisions. 

Heinrich, M. J., Purcell, C. A., Pruijssers, A. J., Zhao, Y., Spurlock III, C. F., Sriram, S., Ogden, K. M., Dermody, T. S., Scholz, M. B., Crooke III, P. S., Karijolich, J., and T. Aune. Increased levels of double-stranded Alu RNAs drive type 1 interferon responses during the relapsing phase of multiple sclerosis. Submitted. 

Fernández de Castro, I., Tenorio, R., Ortega-González, P., Knowlton, J. J., Zamora, P. F., Lee, C. H., Mainou, B. A., Fernández, J. J., Dermody, T. S., and C. Risco. A modified lysosomal organelle and actin mediate non-lytic egress of reovirus. Submitted. 

Silva, L. A., Brynes, A., McAllister, N., Ashbrook, A. W., Khomandiak, S., Morrison, T. E., Diamond, M. S., and T. S. Dermody. Chikungunya virus requires host trafficking protein GBF1 for efficient replication. Manuscript in preparation. 

Pruijssers, A. J., Taylor, G. M., and T. S. Dermody. Neuron-specific NF-kB-dependent gene expression mediates reovirus neuropathogenesis. Manuscript in preparation. 

Manthiram, K., de St. Maurice, A. M., Johnson, M., Johnson, J., Williams, J. V., Correa, H., and T. S. Dermody. Vaccine-strain influenza B associated with myocardial injury in a previously vaccinated child. Manuscript in preparation. 

Silva, L. A., and T. S. Dermody. Chikungunya virus: Epidemiology, replication, disease mechanisms, and prospective intervention strategies. J. Clin. Invest. 127:737-749, 2017. PMCID: PMC5330729 

Sutherland, D. M., Aravamudhan, P., and T. S. Dermody. Orchestra of reovirus receptors: Still searching for a conductor. Adv. Virus Res. In press. PMCID: In progress. 

Matthijnssens, J., Attoui, H., Bányai, K., Brussaard, C. P. D., Chappell, J., del Vas, M., Dermody, T. S., Duncan, R., Fang, Q., Johne, R., Mertens, P. P. C., Mohd Jaafar, F., Mori, H., Patton, J., Sasaya, T., Suzuki, N., Wei, T., and the ICTV Report Consortium. ICTV Virus Taxonomy: Reoviridae. J. Gen. Virol. In press. PMCID: In progress. 

Brown, J. J., Jabri, B., and T. S. Dermody. A viral trigger for celiac disease. PLoS Pathog. In press. PMCID: In progress. 

Tenorio, R., Knowlton, J. J., Zamora, P. F., Fernández de Castro, I., Risco, C., and T. S. Dermody. Formation of neoorganelles for reovirus replication and assembly. Viruses. Manuscript in preparation. 

Chappell, J. D., and T. S. Dermody. Introduction to viruses and viral diseases. In: Bennett, J. E., Dolin, R., and M. J. Blaser (eds.): Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases. Ninth Edition. Elsevier, Philadelphia, In press. 

DiMaio, D., Dermody, T. S., and L. W. Enquist. Reductio ad intellectum. Annu. Rev. Virol. 5:In press, 2018. 

Dermody, T. S., Hirsch, R., Hostetter, M. K., Orange, J. S., and J. W. St. Geme, III. Expanding the pipeline for pediatric physician-scientists. J. Pediatr. In press, 2018. 

Martin JM, Muniz G, Simonian A, Green M and Shaikh N., MPH. Comparison of Bacterial Culture Results Obtained from Nasopharyngeal and Mid-turbinate Swabs in Children with Upper Respiratory Tract Infection Symptoms. Pediatr Infect Dis J. 2018 May 4. doi: 10.1097/INF.0000000000002027. [Epub ahead of print] 

Green M, Covington S, Taranto S, Michaels MG, Wolfe C, Kaul DR. Pediatrics & Donor Derived Disease Transmission: The US OPTN Experience. Pediatr Transplant 2018 Feb;22(1). doi: 10.1111/petr.13115. Epub 2018 Jan 17 

Madan RP, Allen UD, Green M, Höcker M, Michaels MG, Varela-Fascinetto G, and Danziger-Isakov L on behalf of the Pediatric Subgroup for the International Consensus Guidelines on the Management of Cytomegalovirus in Solid Organ Transplantation and the International Pediatric Transplant Association Infectious Disease Committee. Pediatric transplantation case conference: update on cytomegalovirus. Pediatr Transplant. 2018 Sep 10:e13276. doi: 10.1111/petr.13276. [Epub ahead of print] 

Yamada M. Nguyen C, Fadakar P,Ganoza A, Humar A, Shapiro R, Michaels MGGreen M.  Epidemiology and Outcome of Chronic High Epstein-Barr Viral Load Carriage in Pediatric Kidney Transplant Recipients. Pediatr Transplant. 2018 May;22(3):e13147. doi: 10.1111/petr.13147. Epub 2018 Feb 6 

Danziger-Isakov L, Steinbach WJ, Englund JA, Murray A, Maron G, Tuomanen E, Paulsen G, Munoz F, Sweet L, Green MMichaels MG, Halasa N, Dulek D, Madan RP, MD,Herold BC, Fisher BT. A Multi-Center Consortium to Define the Epidemiology and Outcomes of Inpatient Respiratory Viral Infections in Pediatric Solid Organ Transplant Recipients. J Pediatric Infect Dis Soc. 2018 Mar 10. doi: 10.1093/jpids/piy024. [Epub ahead of print] 

Alexander S, Fisher BT, Gaur AH, Dvorak CC, Villaluna D, Dang H, Chen L, Green M, Nieder ML, Fisher B, Bailey LC, Wiernikowski J, Sung L, for the Children’s Oncology Group. Effect of levofloxacin prophylaxis on bacteremia in children with acute leukemia or undergoing hematopoietic stem cell transplantation: a randomized clinical trial. JAMA 2018 2018;320(10):995-1004. doi:10.1001/jama.2018.12512   

Lopez, S, Michaels MGGreen M. Adenovirus infection in pediatric transplant recipients:  Are effective antiviral agents coming our way? Current Opinion in Organ Transplantation. 2018, 23:395-399  

Green MMichaels MG. Opportunistic infections in liver and intestinal transplantation. IN:  Textbook of Pediatric Infectious Diseases. 8th Edition. Eds: Cherry JD, Harrison GJ, Kaplan SK., Steinbach WJ, Hotez PJ/ W.B. Saunders, Philadelphia, PA, Chapter 72; (in press)  

Michael MG, Chong H, Green M. Infections in Immunocompromised Persons IN Nelson’s Textbook of Pediatrics, 20th Edition, Eds: Kleigman, Stanton, St. Geme, Schor,Behrman. Chapter 178 (in press)  

Chiaranunt P., Tometich, J.T., Ji J. and T. W. Hand. T cell proliferation and colitis is initiated by defined intestinal microbes. 2018 J Immunol. Jul 1;201(1):243-250. PMID: 29777027 

Bhattacharjee A and Hand TW. Role of nutrition, infection and the microbiota in the efficacy of oral vaccines. 2018 Clinical Science. Jun 20;132(11):1169-1177. PMID: 29925624 

Castillo PAC and Hand TW. A little fiber goes a long way. Immunity. 2018 May 15;48(5):844-846. PMID: 29768170 

Lin PL & Flynn JL. The end of the binary era: Revisiting the spectrum of tuberculosis. Journal of Immunology. 2018. Accepted for publication.  

Olarte L, Barson WJ, Bradley JS, Tan TQ, Lin PL, Romero J, Givner LB, Hoffman JA, Hulten KG, Mason EO, Kaplan SL. Invasive Pneumococcal Disease in Infants Aged 0-60 days in the United States in the PCV13 Era. Journal of Pediatric Infectious Disease Society.  2018; 7(3):249-252.  

Maiello P, DiFazio R, Cadena A, Rodgers M, Lin PL, Scanga C, Flynn J. Rhesus macaques are more susceptible to progressive tuberculosis compared to cynomolgus macaques: A quantitative comparison. Infect Immun. 2018;86(2). doi: 10.1128/IAI.00505-17.  

Thompson EG, Smitha S, Gideon HP, Braun J, Valvo J, Skinner J., Aderem A, Flynn JL, Lin PL, Zak DE.Prospective discrimination of controllers from progressors early after low-dose Mycobacterium tuberculosis infection of cynomolgus macaques using blood RNA signature. Journal of Infectious Diseases. 2018; 217(8):1318-1322.  

Wong EA, Joslyn L, Grant NL, Klein E., Lin PL, Kirschner D, Flynn JL. Low levels of T cell exhaustion in tuberculous lung granulomas. 2018. Infect Immun doi: 10.1128/IAI.00426-18. 

Mellors TR, Nasir M, Franchina FA, Smolinska A, Blancet L, Flynn JL, Tomko J, O’Malley M, Scanga CA, Lin PL, Wagner J., Hill J.E. Identificatoion of Mycobacterium tuberculosis using volatile biomarkers in culture and exhaled breath. 2018. Journal of Breath Research. doi: 10.1088/1752-7163/aacd18. (Epub ahead of print) 

Olarte L, Kaplan SL, Barson WJ, Romero JR, Lin PL, Tan TQ, Hoffman JA, Bradley JS, Givner LB, Mason EO,  Hulten KG. Invasive serotype 35B pneumococci including an expanding serotype switch lineage. Emerg Infect Dis. 2018; 24(2):405. 

Keshavjee S, Amanullah F, Cattamanchu A., Dobos K, Fox G, Gendelman H, Gordon R, Hesseling A, Hoi LV, Kampmann B, Kana B, Khuller G., Lewinsohn D, Lewinsohn D, Lin PL, Lu L.L., Maartens G., Owen A., Protopopova M, Rengarajan J, Rubin E, Salgame P, Schurr E, Seddon J, Swindells S, Tobin D, Udwadia Z, Walzl G, Srinivasan S, Rustomjee R, Nahid P. Moving toward tuberculosis elimination: Critical issues for research in diagnostics and therapeutics for tuberculosis infection. 2018. American Journal of Respiratory and Critical Care Medicine. Accepted for publication.  

Gregg, RW, Maiello P, Borish HJ, Coleman T, Reed D. White A, Flynn J, Lin PL. Spatial and temporal evolution of lung granulomas in a cynomolgus macaque model of Mycobacterium tuberculosis infection. Radiology of Infectious Diseases. 2018. Accepted for Publication. 

Ganchua SKC, Cadena AM, Maiello P, Gideon HP, Fraser AJ, Junecko BF, Klein EC, Lin PL, Mattila JT, Flynn JL. Lyme nodes are sites of prolonged bacterial persistence during Mycobacterium tuberculosis infection. PLOS Pathogens 2018. Accepted for publication. 

Cadena AM, Hopkins FF, Maiello P, Carey AF, Wong EA, Martin CJ, DiFazio RM, Andersen P, Lin PL, Fortune SM, Flynn JL. Concurrent infection with Mycobacterium tuberculosis confers robust protection PLOS Pathogens 2018. Accepted for publication.  

Cadena A.M., Ma Y.X., Ding T., MacKenzie B., Maiello P., Geber A., Lin P.L., Flynn J.L., Ghedin E. Profiling the airway in the macaque model of tuberculosis reveals variable microbioal dysbiosis and alteration of community structure.  Microbiome 2018. Accepted for publication.  

Farnaes L, Schiff D, McElroy AK, Coufal NG, Crawford JR, Cannavino C. Encephalitis and Thalamic Injury from Neuroinvasive West Nile Virus in Children on Treatment of Acute Lymphoblastic Leukemia. Pediatric Neurology 2018, (80):84-87. PMID 29398166. 

McElroy AK, Muhlberger E, Munoz-Fontela C. Immune barriers of Ebola virus infection. Current Opinion in Virology, 2018 (28):152-160. 

Shrivastava-Ranjana P, Flint M, Bergeron, McElroy AK, Chatterjee P, Albariño CG, Nichol ST, and Spiropoulou CF. Statins suppress Ebola virus infectivity by interfering with glycoprotein processing. mBio, 2018, 9(3):e00660-18. 

de St. Maurice A, Harmon J, Nyakarahuka L, Balinandi S, Tumusiime A, Kyondo J, Mulei S, Namutebi A, Knust B, Shoemaker T, Nichol ST, McElroy AK and Spiropoulou SF. Rift valley fever viral load correlates with the human inflammatory response and coagulation pathway abnormalities in humans with hemorrhagic manifestations. PLoS NTD, 2018, 12(5):e006460  

McElroy AK, Harmon JR, Flietstra TD Nichol ST, Spiropoulou CF. Human biomarkers of outcome following Rift Valley fever virus infection. J Infect Dis, 2018 Jun 28. doi: 10.1093/infdis/jiy393. [Epub ahead of print] 

Brocato R, Wahl V, Hammerbeck C, Josleyn, M, McElroy A, Smith J, Hooper JW. Innate immune responses elicited by Sin Nombre virus or type I IFN agonists protect hamsters from lethal Andes virus infections. Journal of General Virology, 2018 Aug 1. doi: 10.1099/jgv.0.001131. [Epub ahead of print] 

Spengler JR, McElroy AK, Harmon JR, Coleman-McCray JD, Welch SR, Keck JG, Nichol ST, Spiropoulou CF. Human immune cell engraftment does not alter development of severe acute Rift Valley fever in mice. PLoS ONE, 2018 13(7):e0201104. 

Harmon JR, Spengler JR, Coleman-McCray JD, Nichol ST, Spiropoulou CF, McElroy AK. CD4 T cells, CD8 T cells and monocytes coordinate to prevent Rift Valley fever virus encephalitis. Journal of Virology. 2018 In press. 

Freeman MC, Coyne CBGreen MWilliams JV, and Silva LA. Emerging Arboviruses and Implications for Pediatric Transplantation: A Review. Pediatric Transplantation. 2018. In press. 

Malec LM, Cooper J, Rudolph J, Michaels MG, Ragni MV. Prophylactic rtPA in the Prevention of Line-Associated Thrombosis and Infection in Short Bowel Syndrome. Journal of Pediatric Gastroenterology & Nutrition (JPGN) 66 (6):972-975; 2018.  PMID 29135819  

Green M, Covington S, Taranto S, Michaels MG, Wolfe C, Kaul DR. Pediatrics & Donor Derived Disease Transmission: The US OPTN Experience. Pediatric Transplantation. 2018; 22:e13115; PMID 29341396 

Danziger-Isakov L, Steinbach J, Paulsen G, Munoz FM, Sweet LR, Green M, Michaels MG, Englund JA, Murray A, Halasa N, Dulek DE, Pellett Madan R, Herold BC, Fisher BT. A multicenter consortium to define the epidemiology and outcomes of pediatric solid organ transplant recipient with inpatient respiratory virus infection. JPIDS Accepted Feb 2018; 2018 e version :1-8 

Ross SA, Michaels MG, Ahmed A, Sánchez PJ, Bernstein DI, Feja K, Stewart A, Boppana SB, Fowler KB. Contribution of Breastfeeding to False Positive Saliva PCR for Newborn Congenital Cytomegalovirus Screening Journal Infectious Diseases. 2018 May 15;217 (10) 1612-1615 Published online 2018 Feb 1 doi:10.1093/infedis/jiy057. PMCID:PMC 5913650; PMID 29401303 

Yamada M, Nguyen C, Fadakar P, Ganoza A, Humar A, Shapiro R, Michaels MG, Green M. Epidemiology and outcome of chronic high Epstein-Barr viral load carriage in pediatric kidney transplant recipients. Pediatr Transplant 2018;e13147. https//doi.org/10.111/petr.13147  

Kaul DR Tlusty SM, Michaels MG, Limaye AP, Wolfe CR. Donor derived hepatitis C in the era of increasing intravenous drug use: a report of the Disease Transmission Advisory Committee. Clin Transplantation Published online Aug 6, 2018 https://doi.org/10.111/ctr.13370. 

Taubenslag KJ, Michaels MG, Sylvester CL. A child with unilateral conjunctivitis and elevated inflammatory markers. JAMA Ophthalmology. Published online August 23, 2018. doi:10.1001/jamaophthalmol.2018.0936 

Fowler KB, Ross SA, Shimamura M, Ahmed A, Palmer AL, Michaels MG, Bernstein DI, Sánchez PJ, Feja KN, Stewart A, Boppana S. Racial Disparities in the Prevalence of Congenital Cytomegalovirus Infection. J  Peds ACCEPTED  April 2018  

Pellet Madden R, Allen UD, Green M, Höcker B, Michaels MG, Varela_Fascinetto G, Danziger-Isakov L. Pediatric transplantation case conference: update on cytomegalovirus. Accepted Pediatr Transplant July 22, 2018 

Lopez SMC, Campfield BTNowalk AJ. Oral Management for Pediatric Lyme Meningitis. J Pediatric Infect Dis Soc. 2018 Aug 28. doi: 10.1093/jpids/piy072. [Epub ahead of print] PMID: 30169816 

Eddens T, Kaplan DJ, Anderson AJM, Nowalk AJCampfield BT. Insights from the Geographic Spread of the Lyme Disease Epidemic.Clin Infect Dis. 2018 Jun 16. doi: 10.1093/cid/ciy510. [Epub ahead of print] PMID: 29920580 

Ramgopal S, Rosenkranz M, Nowalk AJ, Zuckerbraun NS. Sternoclavicular Arthritis as a Clinical Presentation for Lyme Disease. Pediatrics. 2018 Apr;141(Suppl 5):S466-S469. doi: 10.1542/peds.2017-0725. PMID: 29610173 

Raghunathan, Krishnan, and Anne K. Kenworthy. "Dynamic pattern generation in cell membranes: Current insights into membrane organization." Biochimica et Biophysica Acta (BBA)-Biomembranes (2018). 

Raghunathan, K., Foegeding, N. J., Campbell, A. M., Cover, T. L., Ohi, M. D., & Kenworthy, A. K. (2018). Determinants of raft partitioning of the Helicobacter pylori pore-forming toxin VacA. Infection and immunity, 86(5), e00872-17. 

Brown JJ, Short SP, Stencel-Baerenwald J, Urbanek K, Pruijssers AJ, McAllister N, Ikizler M, Taylor G, Aravamudhan P, Khomandiak S, Jabri B, Williams CS, Dermody TS. Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection. J Virol. 2018 Apr 27;92(10). pii: e02062-17. doi: 10.1128/JVI.02062-17. Print 2018 May 15. PMID:29514905 

Gilbert JR, Taylor GM, Losee JE, Mooney MP, Cooper GM. Molecular analyses in a rabbit model of craniosynostosis: Likely exclusion of known candidate genes as the loci of origin. Cleft Palate Craniofac J, in press. 

Raybuck AL, Cho SH, Li J, Rogers MC, Lee K, Williams CL, Shlomchik M, Thomas JW, Chen J, Williams JV, Boothby MR. B cell-intrinsic mTORC1 promotes GC-defining transcription factor gene expression, somatic hypermutation, and memory B cell generation in humoral immunity. J Immunol 2018 Apr 15;200(8):2627-2639. doi: 10.4049/jimmunol.1701321. PMID: 29531165 

Khuri-Bulos N, Lawrence L, Piya B, Wang L, Fonnesbeck C, Faouri S, Shehabi AA, Vermund SH, Williams JV, Halasa NB. Severe outcomes associated with respiratory viruses in newborns and infants: a prospective viral surveillance study in Jordan. BMJ Open 2018 May 20;8(5):e021898. doi: 10.1136/bmjopen-2018-021898. PMID: 29780032 

Xu J, Zhang Y, Williams JV. Development and optimization of a direct plaque assay for trypsin-dependent human metapneumovirus strains. J Virol Methods. 2018 May 25. pii: S0166-0934(18)30116-2. doi: 10.1016/j.jviromet.2018.05.012. PMID: 29807042 

Rogers MC, Lamens KD, Shafagati N, Johnson M, Oury TD, Joyce S, Williams JV. CD4+ regulatory T cells exert differential functions during early and late stages of the immune response to respiratory viruses. J Immunol 2018 Jul 11. pii: ji1800096. doi: 10.4049/jimmunol.1800096. PMID: 29997123 

Shafagati N, Williams JV. Human metapneumovirus - what we know now. F1000 Faculty Reviews 2018 Feb 1;7:135. 

Schuster JE, Williams JV. Emerging Respiratory Viruses in Children. Infect Dis Clin North Am. 2018 Mar;32(1):65-74. PMID: 29406977 

Rogers MC, Williams JV. Quis Custodiet Ipsos Custodes? Regulation of Cell-Mediated Immune Responses Following Viral Lung Infections. Annu Rev Virol. 2018 Jul 27. doi: 10.1146/annurev-virology-092917-043515. 

Freeman MC, Coyne CBGreen MWilliams JV, and Silva LA. Emerging Arboviruses and Implications for Pediatric Transplantation: A Review. Ped Transplant 2018, in press. 

2017

Jagger BW, Miner JJ, Cao B, Arora N, Smith AM, Kovacs A, Mysorekar IU, Coyne CB, Diamond MS. Gestational stage and IFN-l signaling influence ZIKV infection in utero. 2017 Cell Host & Microbe Sep 13;22(3):366-376.

Corry J, Arora N, Good C, Sadovsky Y, Coyne CB. Organotypic models of type III interferon-mediated protection from Zika virus infections at the maternal-fetal interface. 2017 Proceedings of the National Academy of Science Aug 29;114(35):9433-9438.

Bramley JC, Drummond CG, Lennemann NJ, Good CA, Kim KS, Coyne CB. A Three-Dimensional Cell Culture System To Model RNA Virus Infections at the Blood-Brain Barrier. mSphere. 2017 Jun 21;2(3). pii: e00206-17.

Chang G, Mouillet JF, Mishima T, Chu T, Sadovsky E, Coyne CB, Parks WT, Surti U, Sadovsky Y. Expression and trafficking of placental microRNAs at the feto-maternal interface. The FASEB Journal, 2017 Mar 13.

Dumont TF, Mouillet JF, Bayer A, Gardner CL, Klimstra WK, Wolf DG, Yagel S, Balmir F, Binstock A, Sanfilippo JS, Coyne CB, Sadovsky Y. The expression level of C19MC miRNAs in early pregnancy and in response to viral infection. Placenta, May;53:23-29.

Drummond CG, Bolock, AM, Congrong M, Luke CJ, Good, M, Coyne, CB. Enteroviruses infect human enteroids and induce antiviral signaling in a cell-lineage specific manner. Proceedings of the National Academy of Science 2017, Feb 14;114(7):1672-1677.

Lennemann, NJ and Coyne, CB. Dengue and Zika viruses subvert reticulophagy by NS2B3-mediated cleavage of FAM134B. Autophagy 2017 2017 Feb;13(2):322-332.

Rausch K, Hackett BA, Weinbren NL, Reeder SM, Sadovsky Y, Hunter CA, Schultz DV, Coyne CB, and Cherry S. Screening Bioactives Reveals Nanchangmycin as a Broad Spectrum Antiviral Active against Zika Virus. Cell Reports, 2017 Jan 17.

Arora N, Sadovsky Y, Dermody TS, and Coyne CB. Microbial vertical transmission during human pregnancy. 2017 Cell Host & Microbe, 2017 May 10;21(5):561-567.

Dietrich MH, Ogden KM, Katen SP, Sutherland DM, Reiss K, Carnahan RH, Goff M, Cooper T, Dermody TS, Stehle T. Structural insights into reovirus s1 interactions with serotype-specific neutralizing antibodies. J. Virol. 91:e01621-16, 2017. [Cover illustration] [Featured in JVI Spotlight]

Baldridge MT, Lee S, Brown JJ, McAllister N, Urbanek K, Dermody TS, Nice TJ, Virgin HW. Expression of Ifnlr1 on intestinal epithelial cells is critical to the antiviral effects of interferon-l against norovirus and reovirus. J. Virol. 91: e02079-16, 2017.

Bouziat R, Hinterleitner R, Brown JJ, Stencel-Baerenwald JE, Ikizler M, Mayassi T, Meisel M, Kim SM, Discepolo V, Pruijssers AJ, Ernest JD, Iskarpatyoti JA, Costes LMM, Lawrence I, Palanski BA, Varma M, Zurenski MA, Khomandiak S, McAllister N, Aravamudhan P, Boehme KW, Hu F, Samsom JN, Reinecker H.-C, Kupfer SS, Guandalini S, Semrad CE, Abadie V, Khosla C, Barreiro LB, Xavier RJ, Ng A, Dermody TS, Jabri B. Reovirus infection triggers inflammatory responses to dietary antigens and development of celiac disease. Science. 356:44-50, 2017. [Featured in an editorial] [Faculty of 1000 selection]

Eaton HE, Kobayashi T, Dermody TS, Johnston RN, Jais, PH, Shmulevitz M. African swine fever virus NP868R capping enzyme promotes reovirus rescue during reverse genetics by promoting reovirus protein expression, virion assembly, and RNA incorporation into infectious virions. J. Virol. 91:e02416-16, 2017. [Featured in JVI Spotlight]

Silva LA, Dermody TS. Chikungunya virus: Epidemiology, replication, disease mechanisms, and prospective intervention strategies. J. Clin. Invest. 127:737-749, 2017.

Allen U, Green M. Prevention and Treatment of Influenza Illness: A Seasonal Challenge for Transplant Patients. Pediatric Transplant. 2017; 21(1), 2017 02

Green M. Preventing CMV and EBV in children undergoing organ transplantation: Retrospective studies can only teach us so much. Pediatric Transplant. 2017 21(1), 2017 02

Winstead M, Nowalk A, Ozolek J, Williams JV, Vander Lugt M, Lin PL. Disseminated Lichtheimia ramons infection after hematopoeitic stem cell transplantation in a child with chronic granulomatous disease. Pediatric Infectious Disease Journal. 2017; E pub ahead of print: doi: 10.1097/INF.0000000000001589.

Olarte L, Lin PL, Barson WJ, Romero JR, Tan TQ, Givner LB, Hoffman JA, Bradley JS, Hulten KG, Mason EO, Kaplan SL. Invasive pneumococcal infections in children following transplantation in the pneumococcal conjugate vaccine era. Transplant Infectious Diseases. 2017: 19(1).

Olarte L, Kaplan SL, Barson WJ, Romero JR, Lin PL, Tan TQ, Hoffman JA, Bradley JS, Givner LB, Mason EO, Hultén KG. Emergence of multidrug resistant pneumococcal serotype 35B among US Children. Journal of Clinical Microbiology. 2017; 55(3): 724-34.

Mellors TR, Blanchet L, Flynn JL, Tomko J, O'Malley M, Scanga CA, Lin PL, Hill JE. A new method to evaluate macaque health using exhaled breath: A case study of M. tuberculosis in a BSL-3 setting. Journal of Applied Physiology. 2017 Mar 1;122(3):695-701.

McCullouch M, Lin PL. Globalization of Pediatric Transplantation: The risk of TB or not TB. Pediatric Transplantation. 2017 May;21(3).

Olarte L, Barson WJ, Barson RM, Romero JR, Bradley JS, Tan TQ, Givner LB, Hoffman JA, Lin PL, Hultén KG, Mason EO, Kaplan SL. Pneumococcal pneumonia requiring hospitalization in U.S. children in the 13-valent pneumococcal conjugate vaccine era. Clinical Infectious Diseases. 2017 Jun 15;64(12):1699-1704.

Martin CJ, Cadena AM, Leung VW, Lin PL, Maiello P, Hicks N, Chase MR, Flynn JL, Fortune SM. Digitally Barcoding Mycobacterium tuberculosis reveals in vivo infection dynamic in the macaque model of tuberculosis. Mbio. 2017;8(3).

Jackson L, Madan-Khetarpal S, Naik M, Michaels MG, Riley M. Infant botulism in the very young neonate: a case series. Am J Perinatolo Rep 2017:e163-e166

O’Gorman, MA, Michaels MG, Kaplan SL, Otley A, KociolekLK, Hoffenberg EJ, Kim KS, Nachman S, Pfefferkorn MD, Sentongo T, Sullivan JE, Sears P. A Safety and Pharmacokinetic Study of Fidaxomicin in Children with Clostridium difficile-associated Diarrhea: A Phase 2a Multicenter Clinical Trial. Journal Pediatric Infectious Diseases. Epub, June 2017;1-9.

Ross SA, Sanchez P, Bernstein D, Michaels M, Ahmed A, Palmer A, Feja K, Stewart A, Fowler K, Boppana S. Newborn dried blood spot PCR to identify infants with congenital cytomegalovirus-associated sensorineural hearing loss. Journal of Pediatrics. 2017 May;184:57-61.e1.

Bradley J, Blumer J, Romero JR, Michaels MG, Munoz F, Kimberlin DW, Pahud B, DeBiasi R, Yamamoto G, Roberts G, Hossain M, Shortino D, Yates P, Adams B, Peppercorn. Intravenous Zanamivir in Hospitalized Patients with Influenza. Pediatrics. 2017 Nov;140(5). pii: e20162727.

Rothman MJ, Tepas JJ 3rd, Nowalk AJ, Levin JE, Rimar JM, Marchetti A, Hsiao AL. Development and Validation of a Continuously Age-Adjusted Measure of Patient Condition for Hospitalized Children Using the Electronic Medical Record. J Biomed Inform. 2017 Feb;66:180-193.

Ye Y, Wagner MM, Cooper GF, Ferraro JP, Su H, Gesteland PH, Haug PJ, Millett NE, Aronis JM, Nowalk AJ, Ruiz VM, López Pineda A, Shi L, Van Bree R, Ginter T, Tsui F. A study of the transferability of influenza case detection systems between two large healthcare systems. PLoS One. 2017 Apr 5;12(4):e0174970.

Ferraro JP, Ye Y, Gesteland PH, Haug PJ, Tsui FR, Cooper GF, Van Bree R, Ginter T, Nowalk AJ, Wagner M. The effects of natural language processing on cross-institutional portability of influenza case detection for disease surveillance. Appl Clin Inform. 2017 May 31;8(2):560-580.

Bowen A, Wiesenfeld HC, Kloesz JL, Pasculle AW, Nowalk AJ, Brink L, Elliot E, Martin H, Tarr CL. Notes from the Field: Cronobacter sakazakii Infection Associated with Feeding Extrinsically Contaminated Expressed Human Milk to a Premature Infant - Pennsylvania, 2016. MMWR Morb Mortal Wkly Rep. 2017 Jul 21;66(28):761-762.

Podd BS, Simon DW, Lopez S, Nowalk A, Aneja R, Carcillo JA. Rationale for Adjunctive Therapies for Pediatric Sepsis Induced Multiple Organ Failure. Pediatr Clin North Am. 2017 Oct;64(5):1071-1088. Review.

Taylor GM, Cooper GM, Losee JE, Mooney MP, Gilbert J. Molecular Analysis of Ephrin A4 and Ephrin B1 in a Rabbit Model of Craniosynostosis: Likely Exclusion as the Loci of Origin. Cleft-Palate Craniofacial Journal. 2017 Jan 30.

Wang D, Taylor GM, Gilbert JR, Losee JE, Sodhi C, Hackam DJ, Billiar TJ, and Cooper GM. Enhanced Calvarial Bone Healing in CD11c-TLR4-/- and MyD88-/- Mice. Plastic Reconstructive Surgery. 2017 Apr; 139(4):933-940.

Gilbert JR, Taylor GM, Losee JE, Mooney MP, Cooper GM. Resequencing of the Col1A1 Gene of Oryctolagus Cuniculus Identifies Splicing Error and Single Nucleotide Polymorphisms. Genes and Genomics. 2017 Aug; 39:549-555.

Wang D, Gilbert JR, Taylor GM, Sodhi CP, Hackam DJ, Losee JE, Billiar TR, Cooper GM. TLR4 Inactivation in Myeloid Cells Accelerates Bone Healing of a Calvarial Defect Model in Mice. Plastic Reconstructive Surgery. 2017 Aug; 140(2):296e-306e.

Rowan NR, Wang EW, Kanaan A, Sahu N, Phillips CD, Williams JV, Lee S. Respiratory Viral Detection in the Paranasal Sinuses of Patients with Cystic Fibrosis. American J Rhinology and Allergy 2017 Mar 1;31(2):105-108.

Howard LM, Edwards KM, Zhu Y, Griffin MR, Weinberg GA, Szilagyi PG, Staat MA, Payne DC, Williams JV. Clinical Features of Human Metapneumovirus Infection in Ambulatory Children 5-13 Years of Age. J Pediatr Infect Dis Soc 2017 Mar 24.

Nesmith N, Williams JV, Johnson M, Zhu Y, Marie Griffin MR, Talbot HK. Sensitive diagnostics confirm that influenza C is an uncommon cause of medically attended respiratory illness in adults. Clin Infect Dis 2017 May 25.

Shi T, McAllister DA, O’Brien KL, ... Williams JV… Nair H, for RSV Global Epidemiology Network. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in young children in 2015: a systematic review and modelling study Lancet. 2017 Sept; 390(10098): 946-958

2016

Hawman DW, Fox JM, Ashbrook AW, May NA, Schroeder KS, Torres RM, Dermody TS, Diamond MS, Morrison TE. Pathogenic chikungunya virus evades B cell responses to establish persistence. Cell Reports. 2016;16:1-13.

Meador CB, Parang B, Musser MA, Haliyur R, Owens DA, Dermody TS. A workshop on leadership for senior MD-PhD students. Med Educ Online. 2016;21:e31534.

Pruijssers AJ, Dermody TS. Reovirus. In: Reiss C.S. (ed.): Neurotropic Viral Infections (pp. 337-60). Berlin, Germany: Springer-Verlag; 2016.

Luethy LN, Erickson AK, Jesudhasan PR, Ikizler M, Dermody TS, Pfeiffer JK. Comparison of three neurotropic viruses reveals differences in viral dissemination to the central nervous system. Virology 487:1-10, 2016. [Featured in Virology Highlights]

Case JB, Ashbrook AW, Dermody TS, Denison MR. Mutagenesis of S-adenosyl-L-methionine-binding residues in coronavirus nsp14 N7-methyltransferase demonstrates differing requirements for genome translation and resistance to innate immunity. J. Virol. 90:7248-7256, 2016.

Ashbrook AW, Lentscher AJ, Zamora PF, Silva LA, May NA, Bauer JA, Morrison TE, Dermody TS. Antagonism of the sodium-potassium ATPase impairs chikungunya virus infection. mBio 7:e00693-16, 2016.

Boehme KW, Ikizler M, Iskarpatyoti JA, Wetzel JD, Willis J, Crowe JE, Jr., LaBranche CC, Montefiori DC, Wilson GJ, Dermody TS. Engineering recombinant reoviruses to display gp41 membrane-proximal external region epitopes from human immunodeficiency virus type 1. mSphere 1:e00086-16, 2016.

Bills JL, VanHouten J, Grundy MM, Chalkley R, Dermody TS. Validity of the Medical College Admission Test for predicting MD-PhD student outcomes. Adv. Health Sci. Educ. 21:33-49, 2016.

De Luca M, Green M, Symmonds J, Kleiger SB, Soltys K, Fisher BT. Invasive candidiasis in liver transplant patients: Incidence and risk factors in a pediatric cohort. Pediatric Transplant 2016 Mar;20(2):235-40.

Nguyen-Ha T, Howrie D, Crowley K, Vetterly CG, McGhee W, Berry D, Ferguson E, Polischuk E, Mori Brooks M, Goff J, Stillwell T, Darville T, Thompson AE, Levin JE, Michaels MG, Green M. A quality assessment of a collaborative model of a pediatric antimicrobial stewardship program. Pediatrics. 2016 May;137(5).

Hoberman A, Paradise JL, Rockette HE, Kearney DH, Copelli SJ, Kurs-Lasky M, Colborn K, Block SL, Labella JJ, Lynch TG, Bhatnagar S, Shope TR, Martin JM, Haralam MA, Pope MA, Nagg JP, Green MD, Shaikh N. Shortened antimicrobial treatment for acute otitis media in young children. N Eng J Med. 2016 Dec 22;375(25):2446-2456.

Kusne S, Taranto S, Covington S, Kaul DR, Blumberg EA, Wolfe C, Green M. Coccidiomycosis transmission through organ transplantation: A report of the OPTN Ad Hoc Disease Transmission Advisory Committee. Am J Transplant. 2016 Jul 4.

Abzug MJ, Michaels MG, Wald E, Jacobs RF, Romero JR, Sánchez PJ, Wilson G, Krogstad P, Storch GA, Lawrence R, Shelton M, Palmer A, Robinson J, Dennehy P, Sood SK, Cloud G, Jester P, Acosta EP, Whitley R, Kimberlin D; NIAID Collaborative Antiviral Study Group. A randomized, double-blind, placebo-controlled trial of pleconaril for the treatment of neonates with enterovirus sepsis. J Pediatric Infect Dis Soc. 2016 Mar;5(1):53-62.

Janowski AB, Michaels MG, Martin JM, Green MD. Piperacillin-tazobactam usage at a tertiary pediatric hospital: An antimicrobial stewardship review. J Pediatric Infect Dis Soc. 2016 Sep;5(3):342-5.

Ganapathi L, Danziger-Isakov L, Kotton C, Kumar D, Huprikar S, Michaels MG, Englund JA. Trainee needs in pediatric transplant infectious diseases education. J Pediatric Infect Dis Soc. 2016 Oct 19.

Lawrence KG, Lee B, Dewar S, Shah J, Dohar JE, Nowalk AJ, Martin JM. Bacteroides bacteremia complicating otogenic Lemierre’s syndrome. Int J Pediatr Otorhinolaryngol. 2016;13:53-6.

Nowalk A, Green M. Epstein-Barr virus. Microbiol Spectr. 2016;4(3).

Rottgers SA, Camison L, Mai R, Shakir S, Grunwaldt L, Nowalk AJ, Natali M, Losee JE. Antibiotic use in primary palatoplasty: A survey of practice patterns, assessment of efficacy, and proposed guidelines for use. Plast Reconstr Surg. 2016;137(2):574-82.

Ramgopal S, Obeid R, Zuccoli G, Cleves-Bayon C, Nowalk A. Lyme disease–related intracranial hypertension in children: Clinical and imaging findings. J Neurol. 2016.

Howard LM, Johnson M, Gil AI, Griffin MR, Edwards KM, Lanata CF, Williams JV, Grijalva CG; for the RESPIRA-PERU Group. Molecular epidemiology of rhinovirus detections in young children. Open Forum Infect Dis. 2016 Jan 13;3(1):ofw001.

Bates JT, Pickens JA, Schuster JE, Johnson M, Tollefson SJ, Williams JV, Davis NL, Johnston RE, Schultz-Darken N, Slaughter JC, Smith-House F, Crowe JE Jr. Immunogenicity and efficacy of alphavirus-derived replicon vaccines for respiratory syncytial virus and human metapneumovirus in nonhuman primates. Vaccine. 2016 Feb 10;34(7):950-6.

Miller EK, Linder J, Kraft D, Johnson M, Lu P, Saville BR, Williams JV, Griffin MR, Talbot HK. Hospitalizations and outpatient visits for rhinovirus-associated acute respiratory illness in adults. J Allergy Clin Immunol. 2016 Mar;137(3):734-43.

Dare R, Zhu Y, Williams JV, Griffin MR, Keipp H, Talbot HK. Detection of influenza by real-time RT-PCR is not affected by delays in respiratory specimen processing. J Clin Virol. 2016 Apr 18.

Hastings AK, Amato KR, Wen SC, Peterson LP, Williams JV. Human metapneumovirus small hydrophobic (SH) protein downregulates type I IFN pathway signaling by affecting STAT1 expression and phosphorylation. Virology. 2016 Apr 27;494:248-56.

Hastings AK, Gilchuk P, Joyce S, Williams JV. Novel HLA-A2-restricted human metapneumovirus epitopes reduce viral titers in mice and are recognized by human T cells. Vaccine. 2016 May 23;34(24):2663-70.

Erickson JJ, Rogers MC, Tollefson SJ, Boyd KL, Williams JV. Multiple inhibitory pathways contribute to lung CD8+ T cell impairment and protect against immunopathology during acute viral respiratory infection. J Immunol. 2016 Jul 1;197(1):233-43.

Cherry CB, Griffin MR, Edwards KM, Williams JV, Gil AI, Verastegui H, Lanata CF, Grijalva CG. Spatial and temporal spread of acute viral respiratory infections in young children living in high-altitude rural communities: A prospective household-based study. Pediatr Infect Dis J. 2016 Oct;35(10):1057-61.

El Shesheny R, Halasa NB, Williams JV, Shehabi AA, Faouri S, Kayali G, Khuri-Bulos N. Molecular epidemiology and evolution of A(H1N1) pdm09 and H3N2 viruses in Jordan, 2011–2013. East Mediterr Health J. 2016 Oct 2;22(7):491-502.

Fan RR, Howard LM, Griffin MR, Edwards KM, Zhu Y, Williams JV, Vidal JE, Klugman KP, Gil AI, Lanata CF, Grijalva CG. Nasopharyngeal pneumococcal density and evolution of acute respiratory illnesses in young children, Peru, 2009–2011. Emerg Infect Dis. 2016 Nov;22(11):1996-9.

Maitre NL, Williams JV. Human metapneumovirus in the preterm neonate: Current perspectives. Res Rep Neonatol. 2016;6:41-49.

2015

Eddens T, Elsegeiny W, Nelson MP, Horne W, Campfield BT, Steele C, Kolls JK. Eosinophils contribute to early clearance of Pneumocystis murina infection. J Immunol. 2015 Jul 1;195(1):185-93.

Ivan Y, Ivan S, Ramgopal S, Campfield BT, Streptoccous milleri infections in children: A case report and review of the literature. Infect Dis Clin Prac. 2015 August 11.

Lai CM, Boehme KW, Pruijssers AJ, Parekh VV, Van Kaer L, Parkos CA, Dermody TS. Endothelial JAM-A promotes reovirus viremia and bloodstream dissemination. J. Infect. Dis. 211:383-393, 2015.

Stencel-Baerenwald J, Reiss K, Blaum BS, Colvin D, Li XN, Abel T, Boyd K, Stehle T, Dermody TS. Glycan engagement dictates hydrocephalus induction by serotype 1 reovirus. mBio 6:e02356-14, 2015.

Doyle JD, Stencel-Baerenwald JE, Copeland CA, Rhoads JP, Brown JJ, Boyd KL, Atkinson JB, Dermody TS. Diminished reovirus capsid stability alters disease pathogenesis and littermate transmission. PLoS Pathog. 11:e1004693, 2015.

Stettner E, Dietrich MH, Reiss K, Dermody TS, Stehle T. Structure of serotype 1 reovirus attachment protein s1 in complex with JAM-A reveals a conserved serotype-independent binding epitope. J. Virol. 89:6136-6140, 2015.

Smith SA, Silva LA, Fox JM, Flyak AI, Kose N, Sapparapu G, Khomandiak S, Ashbrook AW, Kahle KM, Fong RH, Swayne S, Doranz BJ, McGee CE, Heise MT, Pal P, Brien JD, Austin SK, Diamond MS, Dermody TS, Crowe JE Jr. Isolation and characterization of broad and ultrapotent human monoclonal antibodies with therapeutic activity against chikungunya virus. Cell Host Microbe. 18:86-95, 2015. [Featured Article]

Mainou BA, Ashbrook AW, Smith EC, Dorset DC, Denison MR, Dermody TS. Serotonin receptor agonist 5-nonyloxytryptamine alters the kinetics of reovirus cell entry. J. Virol. 89:8701-8712, 2015.

Cox RG, Mainou BA, Johnson M, Hastings AK, Schuster JE, Dermody TS, Williams JV. Human metapneumovirus is capable of entering cells by fusion with endosomal membranes. PLoS Pathog. 11:e1005303, 2015.

Miller R, Covington S, Taranto S, Carrico R, Ehsan A, Friedman B, Green M, Ison MG, Kaul D, Kubak B, Lebovitz DJ, Lyon GM, Pruett TL, Teperman L, Vasudev B, Blumberg E. Communication gaps associated with donor-derived infections. Am J Transplant. 2015 Jan;15:259-64.

Kaul DR, Mehta AK, Wolfe CR, Blumberg E, Green M. Ebola virus disease: Implications for solid organ transplantation. Am J Transplant. 2015 Jan 6;15(1)5-6.

Green M, Covington S, Taranto S, Wolfe C, Bell W, Biggins SW, Conti D, DeStefano D, Dominguez E, Ennis D, Gross T, Klassen-Fischer M, Kotton C, LaPointe-Rudow D, Law Y, Ludrosky K, Menegus M, Morris MI, Nalesnik NA, Pavlakis M, Pruett T, Sifri C, Kaul D. Donor-derived transmission events in 2013: A report of the OPTN ad hoc Disease Transmission Advisory Committee (DTAC). Transplantation. 2015;99:282-7.

Green M, Covington S, Blumberg EA. Understanding the risk of donor-derived infections in pediatric transplantation: The time is now. Pediatric Transplantation. 2015 Feb 10;19(1):8-10.

GiaQuinta S, Michaels MG, McCullers JA, Wang L, Fonnesbeck C, O’Shea A, Green M, Halasa NB. Randomized, double-blind comparison of standard-dose versus high-dose trivalent inactivated influenza vaccine in pediatric solid organ transplant recipients. Pediatr Transplant. 2015 Mar;9:219-28.

Lin PL, Flynn JL. CD8 T cells and mycobacterium tuberculosis infection. Seminars in Immunopathology. 2015 May;37(3):239-49.

Kaplan SL, Center KJ, Barson WJ, Lin PL, Romero JR, Bradley JS, Tan TQ, Hoffman JA, Peters TR, Gurtman A, Scott DA, Gruber WC, Hulten KG, Mason EO. Multicenter surveillance of Streptococcus pneumoniae isolates from middle ear and mastoid cultures in the 13-valent pneumococcal conjugate era. Clinic Infect Dis. 2015 May;60(9):1339-45.

Olarte L, Barson WJ, Lin PL, Romero JR, Tan TQ, Givner LB, Bradley JS, Hoffman JA, Hulten KG, Mason EO, Kaplan SL. Impact of the 13-valent pneumococcal conjugate vaccine on pneumococcal meningitis in children. Clin Infect Dis. 2015 Sep;61(5):767-75.

Gideon HP, Phuah JY, Myers AJ, Bryson BD, Rodgers MA, Coleman MT, Maiello P, Rutledge T, Marino S, Fortune SM, Kirschner DE, Lin PL, Flynn JL. Variability in tuberculosis granuloma T cell responses exists, but a balance of pro- and anti-inflammatory cytokines is associated with sterilization. PLOS Pathogens. 2015; 11:e1004603.

Pienaar E, Clifone NA, Lin PL, Dartois V, Mattila JT, Butler R, Flynn J, Kirschner D, Linderman JJ. A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment. J Theoretical Biolog. 2015;367:166-79.

Danziger-Isakov L, Allen U, Englund J, Herold B, Hoffman J, Green M, Gantt S, Kumar D, Michaels MG; American Society of Transplantation, Pediatric Infectious Diseases Society, and International Pediatric Transplant Association. Recommended curriculum for training in pediatric transplant infectious diseases. J Pediatric Infect Dis Soc. 2015 Mar;4(1):4-10.

Abzug MJ, Michaels MG, Wald E, Jacobs RF, Romero JR, Sánchez PJ, Wilson G, Krogstad P, Storch GA, Lawrence R, Shelton M, Palmer A, Robinson J, Dennehy P, Sood SK, Cloud G, Jester P, Acosta EP, Whitley R, Kimberlin D; NIAID Collaborative Antiviral Study Group. A randomized, double-blind, placebo-controlled trial of pleconaril for the treatment of neonates with enterovirus sepsis. J Pediatric Infect Dis Soc. 2015 Apr 16.

Pinninti SG, Ross SA, Shimamura M, Novak Z, Palmer AL, Ahmed A, Tolan RW Jr., Bernstein DI, Michaels MG, Sánchez PJ, Fowler KB, Boppana SB; National Institute on Deafness and Other Communication Disorders CMV and Hearing Multicenter Screening (CHIMES) Study. Comparison of saliva PCR assay versus rapid culture for detection of congenital cytomegalovirus infection. Pediatr Infect Dis J. 2015 May;34(5):536-7.

Kimberlin DW, Jester PM, Sánchez PJ, Ahmed A, Arav-Boger R, Michaels MG, Ashouri N, Englund JA, Estrada B, Jacobs RF, Romero JR, Sood SK, Whitworth MS, Abzug MJ, Caserta MT, Fowler S, Lujan-Zilbermann J, Storch GA, DeBiasi RL, Han JY, Palmer A, Weiner LB, Bocchini JA, Dennehy PH, Finn A, Griffiths PD, Luck S, Gutierrez K, Halasa N, Homans J, Shane AL, Sharland M, Simonsen K, Vanchiere JA, Woods CR, Sabo DL, Aban I, Kuo H, James SH, Prichard MN, Griffin J, Giles D, Acosta EP, Whitley RJ; NIAID Collaborative Antiviral Study Group. Valganciclovir for symptomatic congenital cytomegalovirus disease. N Engl J Med. 2015 Mar 5;372(10):933-43.

*Loria C, *Domm JA, Halasa NB, Heitman E, Miller EK, Xu M, Saville BR, Frangoul H, Williams JV. Human rhinovirus C infections in pediatric hematology and oncology patients. Pediatr Transplant. 2015 Feb;19(1):94-100. *Co-first authors.

Jules A, Grijalva C, Zhu Y, Talbot K, Williams JV, Chaves S, Poehling K, Edwards K, Schaffner W, Shay D, Griffin M. Influenza-related hospitalization and ED visits in children less than 5 years: 2000-2011. Pediatrics. 2015 Jan;135(1):e66-74.

Chen Q, Griffin MR, Nian H, Zhu Y, Williams JV, Edwards KM, Talbot HK. Influenza vaccine prevents medically attended influenza-associated acute respiratory illness in adults 50 years or older. J Infect Dis. 2015 Apr 1;211(7):1045-50.

Hastings AK, Erickson JJ, Schuster JE, Boyd KL, Tollefson SJ, Johnson M, Gilchuk P, Joyce S, Williams JV. Role of type I interferon signaling in human metapneumovirus pathogenesis and control of viral replication. J Virol. 2015 Apr 15;89(8):4405-20.

Oliveira DBL, Iwane MK, Prill MP, Weinberg GA, Williams JV, Griffin MR, Szilagyi PG, Edwards KM, Staat MA, Hall CB, Durigon EL, Erdman DD. Molecular characterization of respiratory syncytial viruses infecting children reported to have received palivizumab immunoprophylaxis. J Clin Virol. 2015 Apr;65:26-31.

Grijalva CG, Goeyvaerts N, Verastegui H, Edwards KM, Gil AI, Lanata CF, Hens N; RESPIRA PERU project (Griffin MR, Williams JV, Edwards KM, Budge PJ, Zhu Y, Johnson M, Grijalva CG, Vidal JE, Klugman KP, Gil AI, Verastegui H, Lanata CF). A household-based study of contact networks relevant for the spread of infectious diseases in the highlands of Peru. PLOS One. 2015 Mar 3;10(3):e0118457.

Lindegren ML, Griffin MR, Williams JV, Edwards KM, Zhu Y, Mitchel E, Fry AM, Schaffner W, Talbot HK. Antiviral treatment among older adults hospitalized with influenza, 2006-2012. PLOS One. 2015 Mar 25;10(3):e0121952.

Bose ME, He J, Shrivastava S, Nelson MI, Bera J, Halpin RA, Town CD, Lorenzi HA, Noyola D, Falcone V, Gerna G, De Beenhouwer H, Videla C, Kok T, Venter M, Williams JV, Henrickson KJ. Sequencing and analysis of global human respiratory syncytial virus A and B genome sequences. PLOS One. 2015 Mar 20;10(3):e0120098.

Talbot HK, Nian H, Zhu Y, Chen Q, Williams JV, Griffin MR. Clinical effectiveness of split-virion versus subunit trivalent influenza vaccines in older adults. Clin Infect Dis. 2015 Apr 15;60(8):1170-5.

Howard LM, Johnson M, Williams JV, Zhu Y, Gil AI, Edwards KM, Griffin MR, Lanata CF, Grijalva CG; for the RESPIRA-PERU Group. Respiratory viral detections during symptomatic and asymptomatic periods in young Andean children. Pediatr Infect Dis J. 2015 Jun 24;10(6):e0130233.

Wu A, Budge PJ, Williams JV, Griffin MR, Edwards KM, Johnson M, Zhu Y, Hartinger S, Verastegui H, Gil AI, Lanata CF, Grijalva C. Incidence and risk factors for respiratory syncytial virus and human metapneumovirus infections among children in the remote highlands of Peru. PLOS One. 2015 Jun 24;10(6):e0130233.

Wen SC, Williams JV. New approaches for immunization and therapy against human metapneumovirus. Clin Vaccine Immunol, 2015. Aug;22(8):858-66.

Wen SC, Schuster JE, Gilchuk P, Boyd KL, Joyce J, Williams JV. Lung CD8+ T cell impairment occurs during human metapneumovirus infection despite virus-like particle (VLP) induction of functional CD8+ T cells. J Virol. 2015 Sep;89(17):8713-26.

Moon TD, Johnson M, Foster MA, Silva WP, Buene M, Valverde E, Morais L, Williams JV, Vermund SH, Brentlinger PE. Identification of invasive Salmonella enterica serovar typhimurium ST313 in ambulatory HIV-infected adults in Mozambique. J Global Infect Dis. 2015 Oct-Dec;7(4):139-42.

Erickson JJ, Lu P, Wen SC, Hastings AK, Gilchuk P, Joyce J, Shyr Y, Williams JV. Acute viral respiratory infection rapidly induces a CD8+ T cell exhaustion-like phenotype. J Immunol. 2015 Nov 1;195(9)4319-30.

Halasa NB, Williams JV, Faouri S, Shehabi S, Vermund SV, Wang L, Fonnesbeck C, Khuri-Bulos N. Natural history and epidemiology of respiratory syncytial virus infection in the Middle East: Hospital surveillance for children under age two in Jordan. Vaccine. 2015 Nov 25;33(47):6479-87.

Schuster JE, Khuri-Bulos N, Faouri S, Shehabi A, Johnson M, Wang L, Fonnesbeck C, Williams JV*, Halasa NB. Human metapneumovirus infection in Jordanian children: Epidemiology and risk factors for severe disease. Pediatr Infect Dis J. 2015 Dec; 34(12):1335-41. *Corresponding author.

Schuster JE, Cox RG, Hastings AK, Boyd KL, Wadia J, Chen Z, Burton DR, Williamson RA, Williams JV. A broadly neutralizing human monoclonal antibody exhibits in vivo efficacy against both human metapneumovirus and respiratory syncytial virus. J Infect Dis. 2015 Jan 15;211(2):216-25.