Abbe N. de Vallejo, MSc, PhD

  • Associate Professor of Pediatrics and Immunology and Scientific Director, Flow Cytometry Core
  • Member, McGowan Institute for Regenerative Medicine, University of Pittsburgh School of Medicine
  • Member, Graduate Program in Microbiology and Immunology, University of Pittsburgh School of Medicine

Administrative Assistant: Cathy Ketchel

Abbe de Vallejo is tenured Associate Professor in the Department of Pediatrics with secondary appointment in the Department of Immunology. He obtained an MSC in Pathobiology from the University of Stirling, Scotland, a PhD in Microbiology and Immunology from the University of Mississippi Medical Center, and Postdoctoral trainings in Molecular Immunology and Rheumatology from Mayo Clinic College of Medicine. Before coming to Pittsburgh, he was Associate Consultant in Rheumatology and Assistant Professor of Medicine at Mayo Medical School. In addition to his current faculty appointments, de Vallejo has appointments at McGowan Institute for Regenerative Medicine and the Division of Rheumatology, UPMC Children’s Hospital of Pittsburgh. He serves as Scientific Director of the Flow Cytometry Core of the John G. Rangos Sr. Research Center. He is actively involved in various educational programs as mentor, co-mentor or research committee member for undergraduates, graduate students, and fellows; as faculty of the Graduate Program in Microbiology and Immunology; and as faculty administrator of the Scholarly Project Program of the Pediatric Rheumatology Fellowship. de Vallejo currently serves in the editorial boards of Frontiers in Immunology and Aging and Disease journals and as permanent member of the National Scientific Advisory Council of the American Federation for Aging Research. He is Fellow of the Royal Society of Medicine. 

Professional and Scientific Society Memberships

  • Growth Hormone Research Society 
  • Gerontological Society of America
  • The Royal Society of Medicine
  • American College of Rheumatology
  • American Association of Immunologists

Education & Training

  • SCM, Pathobiology, University of Stirling
  • PhD, Immunology & Microbiology, University of Mississippi Medical Center
  • Postdoctoral, Molecular Immunology, Mayo Clinic College of Medicine
  • Postdoctoral, Mayo Clinic College of Medicine

Selected Publications

Kritschil R, Zhao S, Dong Q, Lee J, Conover CA, Sowa G, Vallejo AN, Vo N. 2020. Effects of suppressing bioavailability of insulin-like growth factor on age-associated intervertebral disc degeneration. JOR Spine, in press [Epub ahead of print, 2020:e1112, doi.org/10.1002/jsp2.1112]. 

Kuniholm MH, Bramah-Lawani M, Fitzpatrick M, Nouraie SM, Qin S, Huang L, Vallejo AN, Landay AL, Morris A. 2020. T cell activation and monocyte migration markers are associated with distinct measures of pulmonary function in people living with HIV. J Acquir Immune Defic Syndr, in press [Oct 28. doi: 10.1097/QAI.0000000000002544. Online ahead of print]. 

Rajakumar K, Moore CG, Khalid A, Vallejo AN, Virji M, Holick MF, Greenspan SL, Arslanian S, Reis SE. 2020. Effect of Enhanced vitamin D3 supplementation on vascular and metabolic health of vitamin D-deficient overweight and obese children: A randomized clinical trial. Amer J Clin Nutr 111(4):757-768. PMC7138671.

Shaaban CE, Aizenstein HJ, Jorgensen DR, MacCloud RL, Meckes NA, Erickson KI, Glynn NW, Mettenburg J, Guralnik J, Newman AB, Ibrahim TS, Laurienti PJ, Vallejo AN, Pahor M, Rosano C. 2019. Physical Activity and Cerebral Small Vessel Integrity in Older Adults. Med Sci Sports Exer 51(8):1684-1691. PMC6629486. 

Ferguson ID, Griffin P, Yano H, Gaffen SL, Piganelli JD, Dvergsten JA, Michel JJ, Rosenkranz ME, Kietz DA, Vallejo AN. 2018. CD31/IL17-driven inflammatory axis shapes synovitis in juvenile idiopathic arthritis. Frontiers Immunol 9:1802. PMC6087740.

Shaaban CE, Aizenstein HJ, Jorgensen DR, Meckes NA, Erickson KI, Glynn NW, Mettenburg J, Cohen R, Guralnik J, Newman AB, Ibrahim TS, Laurienti PJ, Vallejo AN, Rosano C. 2017. In Vivo Imaging of Venous Side Cerebral Small Vessel Disease in Older Adults: An MRI Method at 7T. Am J Neuroradiol 38(10):1923-1928. PMC5632121.

Michel JJ, Griffin P, Vallejo AN. 2016. Functionally diverse NK-like T cells are indicators and predictors of successful aging. Frontiers Immunol 7:530. PMC5121286.

He M, Kratz LE, Michel JJ, Vallejo AN, Ferris L, Kelley RI, Hoover JJ, Jukic D, Gibson KM, Wolfe L, Ramachandran D, Zwick ME, Vockley J. 2011. Mutations in the SC4MOL gene encoding a novel methyl sterol oxidase cause psoriasiform dermatitis, microcephaly and developmental delay. J Clin Invest 121: 976-984. PMC3049385.

Vallejo AN, Michel JJ, Bale LK, Lemster BH, Borghesi L, Conover CA. 2009. Resistance to age-dependent thymic atrophy in long-lived mice that have deficiency in pregnancy-associated plasma protein A. Proc Nat Acad Sci USA 106:11252-11257. PMC2700140.

Lopez de Padilla C, Vallejo AN, Lacomis D, McNallan KT, Reed AM. 2009. Extra-nodal lymphoid microstructures in inflamed muscle and disease severity in new-onset juvenile dermatomyositis. Arthritis Rheum 60:1160-1172. PMID19333937.

Full Publication List via NIH PubMed  »

Academic and Research Interests

  • Biology of inflammatory syndromes
  • Aging across the lifespan