Alejandro Hoberman, MD

  • Executive Vice Chair of Pediatrics, Vice Chair of Clinical Research, Division Director, General Academic Pediatrics, and Professor of Pediatrics and Clinical and Translational Science
  • President, UPMC Children's Community Pediatrics

Dr. Hoberman graduated from medical school and general pediatrics residency in Buenos Aires, Argentina. He completed a General Academic Pediatrics fellowship at Children’s Hospital of Pittsburgh and joined the faculty at the University of Pittsburgh. He currently heads the Division of General Academic Pediatrics, is the Executive Vice Chair and Vice Chair for Clinical Research in the Department of Pediatrics and has been established as the Jack L. Paradise Distinguished Service Professor in honor of his research mentor. In the area of AOM, Dr. Hoberman has contributed studies to enhance prevention, diagnosis and treatment of this frequently occurring condition. In a study published in JAMA, Dr. Hoberman evaluated the efficacy of influenza vaccine in preventing AOM. He published a series of studies in the NEJM sponsored by the National Institute of Allergy and Infectious Diseases evaluating the efficacy of and adequate duration of antimicrobial therapy in young children with AOM. The study he recently reported in the NEJM was sponsored by the National Institute of Deafness and Other Communication Disorders, evaluated the efficacy of tympanostomy tubes in children with recurrent AOM and received the Clinical Research Forum Top 10 Clinical Research Achievement Award for 2022.

In the area of UTI, Dr. Hoberman evaluated prevalence, diagnosis, treatment and follow-up imaging in children. He published in the NEJM a National Institute of Diabetes and Digestive and Kidney Diseases-sponsored study evaluating the efficacy of antimicrobial prophylaxis in children with vesicoureteral reflux, and received the Clinical Research Forum Top 10 Clinical Research Achievement Award for 2015. The Pittsburgh research team recently completed two NIH-sponsored UTI clinical trials: (1) a collaboration with the University of Pennsylvania evaluating a short-course therapy for UTI in children recently published in JAMA Pediatrics, and (2) led by his colleague Dr. Nader Shaikh, a study evaluating corticosteroids in preventing renal scars in children with febrile UTI published in Pediatric Nephrology.

The quality and influence of Dr. Hoberman’s research is evident from the journals in which they are published, including the NEJM, JAMA, JAMA Pediatrics and Pediatrics. He has served on NIH special emphasis panels, FDA and NIH strategic planning workgroups, American Academy of Pediatrics guideline committees, and as a member of the Clinical Translational Science Award Child Health Oversight Committee. His research has fostered the careers of many others through his roles in fellowship training, as the chief of a large division of General Academic Pediatrics -- the recipient of the 2009 Academic Pediatric Association Outstanding Teaching Award, and in his many other collaborations. In 2014, Dr. Hoberman also received the Academic Pediatric Association Research Award that acknowledges the contribution of an individual in advancing pediatric knowledge through excellence in research, characterized by originality, creativity and methodological soundness. Dr. Hoberman also has administrative responsibilities as the President of UPMC Children’s Community Pediatrics, the largest primary care pediatrics organization in western and central PA with 58 offices including Express Care locations and over 1M yearly visits.

Professional and Scientific Society Memberships

  • Argentine Pediatric Society, Fellow, 1987 
  • Academic Pediatric Association, Member, 1995 
  • American Academy of Pediatrics, Fellow, 1995 
  • Inter-American Society of Pediatric Otolaryngology, Charter Member, 1995 
  • Society for Pediatric Research, Member, 1995 
  • Fellow’s Basic & Clinical Research Awards Committee, Clinical Team Member, 2007-8 
  • Society for Pediatric Research, Member, 1998 
  • American Pediatric Society, Member, 2007 

Education & Training

  • MD, National University of Buenos Aires, 1983
  • Internship in General Pediatrics, Children's Hospital of Buenos Aires, 1984-1985
  • Residency in General Pediatrics, Children's Hospital of Buenos Aires, 1985-1988
  • Fellowship in Ambulatory Pediatrics, UPMC Children's Hospital of Pittsburgh, 1989-1992
  • Physicians Business and Leadership Skills, Katz Graduate School of Business, 2002
  • Leadership Development for Physicians, Harvard School of Public Health, 2004

Selected Publications

Ray KN, Wittman SR, Yabes J, Sabik LM, Hoberman A, Mehrotra A. Telemedicine Visits to Children During the Pandemic: Practice-based Telemedicine vs. Telemedicine-only Providers. Academic Pediatrics (2022) May 16:S1876-2859(22)00247-9. doi: 10.1016/j.acap.2022.05.010.

Barbeau DJ, Martin JM, Carney E, Dougherty E, Doyle JD, Dermody TS, Hoberman A, Williams JV, Michaels MG, Alcorn JF, Duprex WP, McElroy AK. Comparative Analysis of Human Immune Responses Following SARS-CoV-2 Vaccination with BNT162b2, mRNA-1273, or Ad26.COV2.S. npj Vaccines (2022) 7:77; https://doi.org/10.1038/s41541-022-00504-x

Lee C, Preciado D, Hoberman A. Tympanostomy Tubes for Recurrent Otitis Media. N Engl J Med 387;1 (2022) Doi: 10.1056/NEJMclde2202050  

Shaikh N, Lee MC, Stokes LR, Miller E, Kurs-Lasky M, Conway I, Shope TR, Hoberman A. Reassessment of the Role of Race in Calculating the Risk for Urinary Tract Infection: A Systemic Review and Meta-analysis. JAMA Pediatr (2022) 1;176(6):569-575. Doi: 10.1001/jamapediatrics.2022.0700.

Atmar RL, Lyke KE, Deming ME, Jackson LA, Branche AR, El Sahly HM, Rostad CA, Martin JM, Johnston C, Rupp RE, Mulligan MJ, Brady RC, Frenck RW, Bäcker M, Kottkamp AC, Babu TM, Rajakumar K, Edupuganti S, Dobrzynski D, Coler RH, Posavad CM, Arther J, Crandon S, Nayak SU, Szydlo D, Zemanek JA, Dominguez Islas CP, Brown ER, Suthar MS, McElrath MJ, McDermott AB, O’Connell SE, Montefiori DC, Eaton A, Neuzil KM, Stephens DS, Roberts PC, Beigel JH, DMIC 21-0012 Study Group. Homologous and Heterologous Covid-19 Booster Vaccinations. N Engl J Med 2022;386(11):1046-1057. doi: 10.1056/NEJMoa2116414.

Shope TR, Shaikh N, Hoberman A. More Recent Literature Does Not Support Premise or Conclusions. JAMA Pediatr 2022;176(8):826-827. doi: 10.1001/jamapediatrics.2022.1760.

Szigethy EM, Silfee V, Marroquin MA, Pavlick AN, Wallace ML, Williams KR, Hoberman A. A Digital Cognitive-Behavioral Intervention for Depression and Anxiety Among Adolescents and Young Adults. PS in Advance (2022) Doi: 10.1176/appi.ps.202200045.

Burns S, Krishnamurti T, Doan TT, Hanmer J, Hoberman A, Kahn JM, Ray KN. Parent Perceptions of Telemedicine for Acute Pediatric Care: a sequential mixed-methods study. JMIR (2023).

Lobb B, Lee MC, McElheny CL, Doi Y, Yahner K, Hoberman A, Martin JM, Hirota JA, Doxey AC, Shaikh N. Genomic classification and antimicrobial resistance profiling of Streptococcus pneumoniae and Haemophilus influenza isolates associated with paediatric otitis media and upper respiratory infection. BMC Infectious Diseases (2023). https://doi.org/10.1186/s12879-023-08560-x

Shaikh N, Hoberman A. Nonsuperiority of Standard Therapy Compared to Short-Course Therapy in Symptomatic UTIs—Reply.  JAMA Pediatr. Published online October 09, 2023. Doi:10.1001/jamapediatrics.2023.4059

Full Publication List via NIH PubMed »

Academic and Research Interests

  • UTI
  • Urinary tract infection
  • Acute otitis media
  • Artifical inteligence
  • Tympanostomy tubes

Research Grants

5R01AI148159, Children and Colds Telemedicine Use Study (PI: KN Ray), 2020-2024, NICHD $2,075,958

3UM1AI14852-02S5, A Phase 1/2 Study of Delayed Heterologous SARS-CoV-2 Vaccine Dosing (Boost) after Receipt of EUA Vaccines, 2021-2025, NIH/Vanderbilt $784,332