Allyson S. Larkin, MD

  • Associate Professor of Pediatrics
  • Allergy and Immunology Fellowship Program Director, UPMC Children's Hospital of Pittsburgh

Dr. Larkin is an Associate Professor of Pediatrics in the division of Allergy and Immunology. She currently serves as the fellowship program director and also runs the resident and medical student elective in A/I. She has a clinical interest in Pediatric Severe Asthma and established and codirects the Difficult to Treat Asthma Clinic.

Professional and Scientific Society Memberships

  • American Academy of Allergy, Asthma and Immunology, 2008-Present 
  • Pennsylvania Allergy and Asthma Association, 2011-Present 
  • Pennsylvania Medical Society, 2018-Present 

Education & Training

  • BA, Biology, Brandeis University, 1999
  • MD, University of Pittsburgh School of Medicine, 2004
  • Internship in Internal Medicine, Jefferson University Hospital, 2004-2005
  • Residency in Internal Medicine, Jefferson University Hospital, 2005-2007
  • Fellowship in Allergy/Immunology, UPMC Children's Hospital of Pittsburgh, 2008-2010
  • Advanced Fellowship in Allergy/Immunology, UPMC Children's Hospital of Pittsburgh, 2010-2011

Selected Publications

Ross KR, Gupta R, DeBoer MD, Zein J, Phillips BR, Mauger DT, Li C, Myers RE, Phipatanakul W, Fitzpatrick AM, Ly NP, Bacharier LB, Jackson DJ, Celedón JC, Larkin A, Israel E, Levy B, Fahy JV, Castro M, Bleecker ER, Meyers D, Moore WC, Wenzel SE, Jarjour NN, Erzurum SC, Teague WG, Gaston B, Severe asthma during childhood and adolescence: A longitudinal study.  Journal of Allergy and Clinical Immunology.  2020 Jan;145(1):140-146.e9. PubMed PMID:31622688 

Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour NN, Larkin A, Levy BD, Ly NP, Ortega VE, Peters SP, Phipatanakul W, Ramratnam S, Teague WG .  Racial Disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute’s Severe Asthma Research Program.  Journal of Allergy and Clinical Immunology. 2019 June;143 (6):2052-61. PubMed PMID 30635198. 

Sommerfield, C, Nowalk, A., Weiner, D. Larkin, A. Hypersensitivity Pneumonitis and Acute Respiratory Distress Syndrome from E Cigarette Use. Pediatrics. 2018 June; 141(6). PubMed PMID: 29773665.

Wenzel SE, Vitari CA, Shende M, Strollo DC, Larkin A, Yousem SA. Asthmatic granulomatosis: a novel disease with asthmatic and granulomatous features. Am J Respir Crit Care Med. 2012 Sep 15;186(6):501-7. PubMed PMID 22773731

Sharma, S. Almeida, F. Kierstein, S. Hortobagyi, L. Lin, T. Larkin, A. Peterson, J. Yagita, H. Zangrilli, J. Haczku, A. Systemic FasL neutralization increases eosinophilic inflammation in a mouse model of asthma. Allergy. 2011 Mar; 67 (3):328-35. PubMed PMID 22175699

Gomez, M., Lee, A., Reddy, B., Muir, A., Soong, G., Pitt, A., Cheung, A., Prince, A.  Staphylococcus aureus protein A induces airway epithelial inflammatory responses by activating TNFR1. Nature Medicine. 2004 Aug;10 9(8): 842-48. PubMed PMID 15247912

Ratner, A.J., Bryan, R., Weber, A., Nguyen, S., Barnes, D., Pitt, A.S., Gelber, S.,Cheung, A., Prince, A. Cystic fibrosis pathogens activate calcium-dependent mitogen activated protein kinase signaling pathways in airway epithelial cells. J Biol Chem. 2001 Jun 1; 276 (22): 19267-75 PubMed PMID 11278360

Grandis, J.R., Drenning, S.D., Chakraborty, A., Zhou, M.Y., Zeng, Q., Pitt, A.S., Tweardy, D.J. Requirement of Stat3 but not Stat1 Activation for Epidermal Growth Factor Receptor-mediated Cell Growth in Vitro. Journal of Clinical Investigation. 1998 October; 102(7): 1385-92. PubMed PMID 9769331 

Full Publication List via NIH PubMed »

Research Grants

Development of Food Allergy After Solid Organ Transplant, 2019-Present

Severe Asthma Clinic Patient Characteristics Database, 2019-Present 

Manuscript of Parasitic Infections Detected in Allergy Clinic, 2019-Present

1 U01 HL119952, Vitamin D to Prevent Severe Asthma Exacerbations in High-Risk Children, (PI, effort 5%), 2015-2020, $3,523,385

5 U10 HL109086-02, Severe Asthma Research Program, (PI, effort 5%), 2012-Present, $452,500