Anna F. Wang-Erickson, PhD

  • Assistant Professor of Pediatrics and Associate Director, Institute for Infection, Inflammation, and Immunity in Children

Anna is the Associate Director of the newly established Institute for Infection, Inflammation, and Immunity in Children (i4Kids), a unique joint research effort with the University of Pittsburgh and the UPMC  Children's Hospital of Pittsburgh  focused on improving children’s health by combatting infectious and inflammatory diseases through catalyzing new multi-disciplinary collaborations across the health sciences, natural and physical sciences, and computer science. 

Before joining the faculty at Pitt, she was  based at University College London in the UK, managing the  operations and £6.8 million research portfolio of the newly created National Institute for  Health Research Global Health (NIHR)  Research Unit on Mucosal Pathogens (MPRU), working  with research partners on projects across the UK, The Gambia, Ghana, Mali, Malawi, Kenya, South Africa, and Uganda to improve the prevention of pneumonia, meningitis, and sepsis.  She was  also responsible for developing the training strategy for the Unit's postdoctoral researchers and PhD students. 

She  received her PhD in 2015 from the Biological Biomedical Sciences program and the  Leder Human Biology and Translational Medicine program  at Harvard Medical School.

Professional and Scientific Society Membership

  • Sigma Xi, 2006
  • Association of Research Managers and Administrators, 2018

Education & Training

  • BS, Princeton University, 2006
  • PhD, Harvard University, 2015
  • Postdoctoral Fellow, Harvard University, 2017

Selected Publications

Bradley LH, Kleiner RE, Wang AF, Hecht MH, Wood DW. An intein-based genetic selection allows the construction of a high-quality library of binary patterned de novo protein sequences. Protein Eng Des Sel. 2005 Apr;18(4):201-7. doi: 10.1093/protein/gzi020. Epub 2005 Apr 22. PMID: 15849217. 

Arai R, Kobayashi N, Kimura A, Sato T, Matsuo K, Wang AF, Platt JM, Bradley LH, Hecht MH. Domain-swapped dimeric structure of a stable and functional de novo four-helix bundle protein, WA20. J Phys Chem B. 2012 Jun 14;116(23):6789-97. doi: 10.1021/jp212438h. Epub 2012 Apr 10. PMID: 22397676. 

Camp AH, Wang AF, Losick R. A small protein required for the switch from {sigma}F to {sigma}G during sporulation in Bacillus subtilis. J Bacteriol. 2011 Jan;193(1):116-24. doi: 10.1128/JB.00949-10. Epub 2010 Oct 29. PMID: 21037003; PMCID: PMC3019954. 

Traag BA, Ramirez-Peralta A, Wang Erickson AF, Setlow P, Losick R. A novel RNA polymerase-binding protein controlling genes involved in spore germination in Bacillus subtilis. Mol Microbiol. 2013;89(1):113‐122. doi:10.1111/mmi.12262 

Flanagan KA, Comber JD, Mearls E, Fenton C, Wang Erickson AF, Camp AH. A Membrane-Embedded Amino Acid Couples the SpoIIQ Channel Protein to Anti-Sigma Factor Transcriptional Repression during Bacillus subtilis Sporulation. J Bacteriol. 2016 Apr 14;198(9):1451-63. doi: 10.1128/JB.00958-15. PMID: 26929302; PMCID: PMC4836239. 

Wang Erickson AF, Deighan P, Chen S, Barrasso K, Garcia CP, Martínez-Lumbreras S, Alfano C, Krysztofinska EM, Thapaliya A, Camp AH, Isaacson RL, Hochschild A, Losick R. A novel RNA polymerase-binding protein that interacts with a sigma-factor docking site. Mol Microbiol. 2017 Aug;105(4):652-662. doi: 10.1111/mmi.13724. Epub 2017 Jun 19. PMID: 28598017; PMCID: PMC5558796. 

Wang Erickson AF, Deighan P, Garcia CP, Weinzierl ROJ, Hochschild A, Losick R. An Amino Acid Substitution in RNA Polymerase That Inhibits the Utilization of an Alternative Sigma Factor. J Bacteriol. 2017;199(14):e00277-17. Published 2017 Jun 27. doi:10.1128/JB.00277-17 

Full Publication List via NIH PubMed

Research Grants

Wellcome Trust Public Engagement Fund, All for One and One for All? (Advisory Board), 2019-2021, £156,802.

Pitt Momentum Teaming Grant, Pittsburgh Phage Project (Co-I), 2020-2021, $60,000.

NIH 1UO1P001051-01, New Vaccine Surveillance Network (Co-I) 2016-2021, $2,214,285.