Brighid Moran O'Donnell, MD

  • Assistant Professor of Pediatrics

O'Donnell's primary academic focus includes teaching and mentoring both undergraduates and medical students. She developed the curriculum and directed a Pediatric Bench to Bedside course, an undergraduate Honors College seminar course which provided students with the necessary skills to interrogate clinical cases, discover the scientific process, and understand the structure of academic research. O’Donnell is active in the School of Medicine, most notably she is a member of both the Curriculum and Admission Committees. She directs the Pediatric Bootcamp course for graduating fourth year medical students. O'Donnell also serves as a mentor to first year medical students as a FAST advisor (Faculty and Students Together) in the Office of Student Affairs. She is currently working on strategies to improve medical student wellness.

Professional and Scientific Society Memberships

  • American Academy of Pediatrics, 2009-Present
  • Pennsylvania Medical Society, 2009-2013

Education & Training

  • BS, Pre-Medicine, The Pennsylvania State University, 2004
  • MD, Temple University School of Medicine, 2009
  • Residency in Pediatrics and Chief Resident, Jefferson Medical College/A.I. duPont Hospital for Children, 2009-2013
  • Fellowship in Neonatal/Perinatal Medicine, University of Pittsburgh Medical Center, 2013-2016

Selected Publications

Gillette WK, Esposito D, Frank PH, Zhou M, Yu LR, Jozwik C, Zhang X, McGowan BM, Jacobowitz DM, Pollard HB, Hao T, Hill DE, Vidal M, Conrads TP, Veenstra TD, Hartley JL. Pooled ORF Expression Technology (POET): Using Proteomics to Screen Pools of Open Reading Frames for Protein Expression. Molecular and Cellular Proteomics. 2005 Nov; 4(11): 1647-1652. Cited in PubMed; PMID: 16113400.

Pollard HB, Eidelman O, Jozwik C, Huang W, Srivastava M, Ji XD, McGowan BM, Norris CF, Todo T, Darling T, Mogayzel PJ, Zeitlin PL, Wright J, Guggino WB, Metcalf E, Driscoll W, Mueller G, Paweletz C, Jacobowitz DM. De Novo Biosynthetic Profiling of High Abundance Proteins in Cystic Fibrosis Lung Epithelial Cells. Molecular and Cellular Proteomics. 2006 Sep; 5(9): 1628-1637. Cited in PubMed; PMID: 16829594.

O'Donnell BM, Mackie TD, Subramanya AR, Brodsky JL. Endoplasmic reticulum-associated degradation of the renal potassium channel, ROMK, leads to type II Bartter syndrome. J Biol Chem. 2017 Aug 4;292(31):12813-12827. PMID: 28630040

Academic and Research Interests

  • Medical Education
  • Bartter Syndrome
  • ROMK
  • Endoplasmic Reticulum-Association Degradation