Bryan H. Goldstein, MD

  • Assistant Professor of Pediatrics
  • Director, Cardiac Catheterization & Intervention, UPMC Children's Hospital of Pittsburgh

Bryan H. Goldstein, MD is Director of the Cardiac Catheterization Laboratory and Interventional Cardiology Service at UPMC Children’s Hospital of Pittsburgh and Associate Professor of Pediatrics at University of Pittsburgh School of Medicine.  Dr. Goldstein joined the CHP Heart Institute in 2019, arriving from Cincinnati Children’s Hospital, where he served as Associate Director of Cardiac Catheterization & Intervention. A native of Boston, MA, Dr. Goldstein graduated with Honors from Amherst College, where he was a goalie on the men's lacrosse team. He earned his medical degree with Honors from Boston University School of Medicine. He completed his pediatric residency at Children's Hospital Boston (BCRP) and his pediatric and interventional cardiology fellowships at the University of Michigan (C.S. Mott Children's Hospital) in Ann Arbor.

 

Dr. Goldstein’s clinical expertise is in congenital cardiac catheterization. He is interested in invasive physiologic assessment of complex congenital heart disease (CHD), including single ventricle physiology, as well as minimally invasive transcatheter therapies. Dr. Goldstein has particular clinical interests in transcatheter valve therapies, neonatal palliations (including PDA stent and RVOT stent), complex pulmonary artery rehabilitation and innovative hybrid therapies.

 

Dr. Goldstein’s research interests include novel transcatheter interventions and long-term outcomes following interventions for CHD. He is co-founder and Vice President of the Congenital Cardiac Research Collaborative (CCRC), a multicenter quality improvement and research collaborative that aims to improve care for children and young adults with CHD through the conduct of rigorous outcomes research and clinical trials. An additional research focus includes long-term functional outcomes in patients with Fontan circulation, including investigations of vascular and diastolic function in the Fontan population. Dr. Goldstein has received grant funding from the American Heart Association and NIH/NHLBI. He has served as Principal Investigator on numerous national and international clinical trials including the Pediatric Heart Network FUEL, FUEL OLE and FALD clinical trials, Nit-Occlud® PDA Post-Approval Study, Gore® ASSURED Cardioform ASD Occluder Pivotal Trial and Edwards Lifesciences COMPASSION XT Post-Approval Study.

 

Dr. Goldstein is a Fellow of the American College of Cardiology (FACC), the Society of Cardiovascular Angiography and Interventions (FSCAI), and the American Academy of Pediatrics (FAAP) and an active member of the American Heart Association (AHA). He received the Pediatric Interventional Cardiology Symposium Young Leadership Award in 2013 and was elected to the Emerging Leader Mentorship program in 2015-2017 through SCAI, ACC and CRF.

Professional and Scientific Society Memberships

  • American Medical Association, 2000-2005 
  • Massachusetts Medical Society, 2000-2007
  • Alpha Omega Alpha Honor Medical Society, 2003-Present 
  • American Academy of Pediatrics, 2004-Present (Fellow AAP, 2012)
  • American Heart Association, 2006-Present 
  • American College of Cardiology, 2007-Present (Fellow AAP, 2014)
  • Society for Cardiovascular Angiography and Interventions, 2009-Present (Fellow SCAI, 2015)

Education & Training

  • BA, Law, Jurisprudence and Social Thought, Amherst College, 1999
  • Certificate in the Culinary Arts, Boston University School of Hospitality, 2000
  • MD, Boston University School of Medicine, 2004
  • Internship/Residency in Pediatrics, Children's Hospital Boston and Boston Medical Center, 2004-2007
  • Fellowship in Pediatric Cardiology, C.S. Mott Children's Hospital, 2007-2010
  • Fellowship in Pediatric Interventional Catheterization, C.S. Mott Children's Hospital, 2010-2011

Selected Publications

Nicholson GT, Goldstein BH, Gao K, Sachdeva R, Lang SM, Gillespie S, Kim SH, Petit CJ.  Echocardiographic versus Angiographic Measurement of the Aortic Valve Annulus in Children Undergoing Balloon Aortic Valvuloplasty: Method Affects Outcomes. Cardiol Young. 2020 Dec;30(12):1923-1929. PMID: 33050969.

 

Alsaied T, Moore RA, Truong V, Rattan M, Lang SM, Averin K, Veldtman GR, Urbina EM, Redington AN, Mazur W, Cnota JF, Taylor MD, Goldstein BH.  Myocardial Fibrosis, Diastolic Dysfunction and Elevated Liver Stiffness in the Fontan Circulation. Open Heart. 2020 Oct;7(2):e001434. PMID: 33109703.

 

Shahanavaz S, Zahn E, Levi D, Aboulhosn J, Hascoet S, Qureshi A, Porras D, Moragn G, Bauser-Heaton H, Martin MH, Keeshan B, Asnes JD, Kenny D, Ringewald J, Zablah J, Ivy M, Morray B, Torres A, Berman D, Gillespie M, Chaszczewski K, Zampi JD, Walsh K, Plessis J, Goldstein BH, Sathanandam S, Karsenty C, Balzer D, McElhinney DB.  Transcatheter Pulmonary Valve Replacement with Sapien Valves: Early Outcomes in a Large Multicenter Cohort. J Am Coll Cardiol. 2020 Dec 15;76(24):2847-2858. PMID: 33303074.

 

Pompa AG, Johnson JA, Goldstein BH.  Post-Natal Diagnosis and Catheter-Based Management of Premature Fetal Ductal Closure Presenting as Unilateral Pulmonary Artery Thrombosis and Right Ventricular Failure. Cardiol Young. 2020 Dec 21:1-3. PMID: 33345766.

 

Goldstein BH, Qureshi AM, Meadows JJ, Nicholson GT, Bauser-Heaton H, Petit CJ, Pater C, Kelleman M, Mozumdar N, Aggarwal V, Agrawal H, Ligon RA, Christensen J, McCracken C, Glatz AC.  Impact of Treatment Strategy on Outcomes in Isolated Pulmonary Artery of Ductal Origin: A Multicenter Report from the Congenital Catheterization Research Collaborative. Pediatr Cardiol. 2021 Jan 4. PMID: 33394118.

 

Pickles D, Lannon C, Wooton S, Eversole M, Rychik J, Wright G, on behalf of the Fontan Outcomes Network Design Team [including Goldstein B].  The Future is Now for Transforming Outcomes Nationally: The Fontan Outcomes Network. Prog Pediatr Cardiol. 2020; 59:101302.

 

Goldstein BH, Petit CJ, Qureshi AM, McCracken CE, Kelleman MS, Nicholson GT, Law MA, Meadows JJ, Zampi JD, Shahanavaz S, Mascio CE, Chai PJ, Romano JC, Asztalos IB, Kamsheh AM, Healan SJ, Smith J, Ligon RA, Pettus JA, Juma S, Raulston JJ, Huskey JL, Batlivala SP, Pajk AL, Eilers LF, Khan HQ, Merritt TC, Candor M, Juergensen S, Rinderknecht FA, Bauser-Heaton H, Glatz AC.  Comparison of Management Strategies for the Neonate with Symptomatic Tetralogy of Fallot. J Am Coll Cardiol. 2021;77:1093-106. PMID: 33632484.

 

Qureshi AM, Caldarone CA, Romano JC, Chai PJ, Mascio CE, Glatz AC, Petit CJ, McCracken CE, Kelleman MS, Nicholson GT, Meadows JJ, Zampi JD, Shahanavaz S, Law MA, Batlivala SP, Goldstein BH; Congenital Cardiac Research Collaborative Investigators.  Comparison of Management Strategies for the Neonate with Symptomatic Tetralogy of Fallot and Weight Less than 2.5 kg. J Thorac Cardiovasc Surg. 2021 Feb 3. PMID: 33726912.

 

Pettus JA, Pajk AL, Glatz AC, Petit CJ, Goldstein BH, Qureshi AM, Nicholson GT, Meadows JJ, Shahanavaz S, Zampi JD, Law MA, Kelleman MS, McCracken CM and the Congenital Cardiac Research Collaborative.  Data Quality Methods Through Remote Source Data Verification Auditing: Results from the Congenital Cardiac Research Collaborative. Cardiol Young. 2021 Mar 17:1-6. PMID: 33726868.

 

Alsaied T, Rathod RH, Aboulhosn JA, Anderson JB, Baumgartner H, Brown DW, Cordina R, D’dudekem Y, Ginde S, Goldberg DJ, Goldstein BH, Lubert AM, Oechslin E, Opotowsky AR, Rychik J, Schumacher KR, Valente AM, Wright G, Veldtman GR.  Reaching Consensus for Unified Medical Language in Fontan Care. ESC Heart Fail 2021.

 

View MyNCBI Bibliography » 

Academic and Research Interests

  • Congenital Heart Disease
  • Fontan Circulation
  • Endothelial Dysfunction
  • Diastolic Dysfunction
  • Novel Transcatheter Therapies
  • Transcatheter Valve Implantation
  • Neonatal Palliation
  • Outcomes Research

Research Grants

UM-5500018955, Goldstein (PI), 8/1/20 – 7/31/22, University of Michigan, $2,500, Role: Site PI – 5% effort, “Neurocognitive Function of Adolescents and Young Adults with Repaired Complex Congenital Heart Disease after Recent Cardiac Re-interventions: A Pilot Study”