Bryan H. Goldstein, MD

  • Professor of Pediatrics
  • Director, Cardiac Catheterization & Intervention, UPMC Children's Hospital of Pittsburgh

Administrative Assistant: Wanda Gilliam 

Bryan H. Goldstein, MD is Director of the Cardiac Catheterization Laboratory and Interventional Cardiology Service at UPMC Children’s Hospital of Pittsburgh and Professor of Pediatrics at University of Pittsburgh School of Medicine.  Dr. Goldstein joined the CHP Heart Institute in 2019, arriving from Cincinnati Children’s Hospital, where he served as Associate Director of Cardiac Catheterization & Intervention. A native of Boston, MA, Dr. Goldstein graduated with Honors from Amherst College, where he was a goalie on the men's lacrosse team. He earned his medical degree with Honors from Boston University School of Medicine. He completed his pediatric residency at Children's Hospital Boston (BCRP) and his pediatric and interventional cardiology fellowships at the University of Michigan (C.S. Mott Children's Hospital) in Ann Arbor.

Dr. Goldstein’s clinical expertise is in congenital cardiac catheterization. He is interested in invasive physiologic assessment of complex congenital heart disease (CHD), including single ventricle physiology, as well as minimally invasive transcatheter therapies. Dr. Goldstein has particular clinical interests in transcatheter valve therapies, neonatal palliations (including PDA stent and RVOT stent), complex pulmonary artery rehabilitation and innovative hybrid therapies.

Dr. Goldstein’s research interests include novel transcatheter interventions and long-term outcomes following interventions for CHD. He is co-founder and Vice President of the Congenital Cardiac Research Collaborative (CCRC), a multicenter research and quality improvement collaborative that aims to improve care for children and young adults with CHD through the use of prospective registries and clinical trials. An additional research focus includes long-term functional outcomes in patients with Fontan circulation, including investigations of vascular and diastolic function in the Fontan population. Dr. Goldstein has received grant funding from the American Heart Association and NIH/NHLBI. He has served as Principal Investigator on numerous national and international clinical trials including the Pediatric Heart Network FUEL, FUEL OLE and FALD clinical trials, Nit-Occlud® PDA Post-Approval Study, Gore® ASSURED Cardioform ASD Occluder Pivotal Trial, Edwards Lifesciences COMPASSION XT Post-Approval Study, Edwards Lifesciences Alterra Adaptive Prestent Post-Approval Study and Medtronic Harmony TPV Post-Approval Study.

Dr. Goldstein is a Fellow of the American College of Cardiology (FACC), the Society of Cardiovascular Angiography and Interventions (FSCAI), the Pediatric Interventional Cardiology Society (PICS) and the American Academy of Pediatrics (FAAP) and an active member of the American Heart Association (AHA). He received the Pediatric Interventional Cardiology Symposium Young Leadership Award in 2013 and was elected to the Emerging Leader Mentorship program in 2015-2017 through SCAI, ACC and CRF.

Professional and Scientific Society Memberships

  • American Medical Association, 2000-2005 
  • Massachusetts Medical Society, 2000-2007
  • Alpha Omega Alpha Honor Medical Society, 2003-Present 
  • American Academy of Pediatrics, 2004-Present (Fellow AAP, 2012)
  • American Heart Association, 2006-Present 
  • American College of Cardiology, 2007-Present (Fellow AAP, 2014)
  • Society for Cardiovascular Angiography and Interventions, 2009-Present (Fellow SCAI, 2015)
  • Pediatric and Congenital Interventional Cardiology Society, 2021-Present (Fellow PICS, 2021)

Education & Training

  • BA, Law, Jurisprudence and Social Thought, Amherst College, 1999
  • Certificate in the Culinary Arts, Boston University School of Hospitality, 2000
  • MD, Boston University School of Medicine, 2004
  • Internship/Residency in Pediatrics, Children's Hospital Boston and Boston Medical Center, 2004-2007
  • Fellowship in Pediatric Cardiology, C.S. Mott Children's Hospital, 2007-2010
  • Fellowship in Pediatric Interventional Catheterization, C.S. Mott Children's Hospital, 2010-2011

Selected Publications

Gunsaulus M, Wang L, Christopher A, Feingold BD, Squires J, Horslen S, Hoskoppal A, Rose-Felker K, West SC, Trucco S, Squires J, Olivieri L, Kreutzer J, Goldstein BH, Alsaied T.  Cardiac MRI Derived Inferior Vena Cava Cross-Sectional Area Correlates with Measures of Fontan Associated Liver Disease. Pediatr Cardiol. 2022 Dec 1. PMID: 36454265.

Van den Eynde J, Possner M, Alahdab F, Veldtman G, Goldstein BH, Rathod RH, Hoskoppal AK, Saraf A, Feingold B, Alsaied T. Thromboprophylaxis in Patients with Fontan Circulation: A network meta-analysis. J Am Coll Cardiol. 2023 Jan 31;81(4):374-389. PMID: 36697138.

Meadows JJ, Bauser-Heaton H, Petit CJ, Goldstein BH, Qureshi AM, McCracken CE, Kelleman MS, Nicholson GT, Law MA, Zampi JD, Shahanavaz S, Chai PJ, Romano JC, Batlivala SP, Maskatia SA, Asztalos IB, Eilers L, Kamsheh AM, Healan SJ, Smith JD, Ligon RA, Dailey-Schwartz A, Pettus JA, Pajk AL, Glatz AC, Mascio CE. Comparison of Treatment Strategies for Neonates with Tetralogy of Fallot and Pulmonary Atresia. J Thorac Cardiovasc Surg. 2023 Jan 14. PMID: 36828672.

Holzer R, Batlivala SP, Boe B, Goldstein BH, Gudausky T, Hasan B, O’Byrne M, Quinn B, Sathanandam S, Shahanavaz S, Trucco SM, Zampi JD, Bergersen L. The Need for Surgery After Vascular or Cardiac Trauma, or Technical Adverse Events in the Congenital Cardiac Catheterization Laboratory. Pediatr Cardiol. 2023 Feb 20. PMID: 36806971.

Barry OM, Gudausky TM, Balzer DT, Bocks ML, Boe BA, Callahan R, El-Said H, Farias MJ, Foerster S, Goldstein BH, Holzer RJ, Janssen D, Levy P, O'Byrne ML, Rahman G, Sathanandam S, Shahanavaz S, Whiteside W, Turner ME. Safety and Short-Term Outcomes for Infants < 2.5 kg Undergoing PDA Device Closure: A C3PO Registry Study. Pediatr Cardiol. 2023 Aug;44(6):1406-1413. PMID: 36995404.

Goldberg DJ, Hu C, Lubert AM, Rathod RH, Penny DJ, Petit CJ, Schumacher KR, Ginde S, Williams RV, Yoon JK, Kim GB, Nowlen TT, DiMaria MV, Frischhertz BP, Wagner JB, McHugh KE, McCrindle BW, Cartoski MJ, Detterich JA, Yetman AT, John AS, Richmond ME, Yung D, Payne RM, Mackie AS, Davis CK, Shahanavaz S, Hill KD, Almaguer M, Zak V, McBride MG, Goldstein BH, Pearson GD, Paridon SM; Pediatric Heart Network Investigators. The Fontan Udenafil Exercise Longitudinal Trial: Subgroup Analysis. Pediatr Cardiol. 2023 Jun 29. PMID: 37382636.

Abdulkarim A, Shaji S, Elfituri M, Gunsaulus M, Zafar MA, Zaidi AN, Pass RH, Feingold B, Kurland G, Kreutzer J, Ghassemzadeh R, Goldstein B, West S, Alsaied T. Pulmonary Complications in Patients With Fontan Circulation: JACC Review Topic of the Week. J Am Coll Cardiol. 2023 Jun 27;81(25):2434-2444. PMID: 37344046.

Petit CJ, Glatz AC, Goldstone A, Law MA, Romano JC, Maskatia SA, Chai PJ, Zampi JD, Meadows JJ, Nicholson GT, Shahanavaz S, Qureshi AM, McCracken CE, Mascio CE, Batlivala SP, Asztalos IB, Healan SJ, Smith JD, Pettus JA, Beshish A, Raulston JEB, Hock KM, Pajk AL, Goldstein BH. Pulmonary Artery Hypoplasia in Neonates with Tetralogy of Fallot. J Am Coll Cardiol. 2023 Aug 15;82(7):615-627. PMID: 37558375.

Shahanavaz S, Qureshi AM, Petit CJ, Goldstein BH, Glatz AC, Bauser-Heaton H, McCracken CE, Kelleman MS, Nicholson GT, Zampi JD, Pettus J, Meadows J, Hock KM, Law MA. Outcomes Following Balloon Pulmonary Valvuloplasty in Symptomatic Neonates with Tetralogy of Fallot – CCRC Study. J Soc Cardiovasc Angio Interv. 2023.

Edelson J, Zak V, Goldberg D, Fleming G, Mackiel A, Patel JK, Files M, Downing T, Richmond M, Acheampong B, Cartoski M, Detterich J, McCrindle B, McHugh K, Hansen J, Wagner J, Di Maria M, Weingarten A, Nowlen T, Yoon JK, Kim GB, Williams R, Whitehill R, Kirkpatrick E, Yin S, Ermis P, Lubert A, Stylianou M, Freemon D, Hu C, Garuba OD, Frommelt P, Goldstein BH, Parison S, Garg R. The Effect of Udenafil on Heart Rate and Blood Pressure in Adolescents with the Fontan Circulation. Am J Cardiol. 2023.

View MyNCBI Bibliography » 

Academic and Research Interests

  • Congenital Heart Disease
  • Fontan Circulation
  • Endothelial Dysfunction
  • Diastolic Dysfunction
  • Novel Transcatheter Therapies
  • Transcatheter Valve Implantation
  • Neonatal Palliation
  • Outcomes Research

Research Grants

MDT20057CON003, Goldstein (PI), 10/10/21 – 10/19/31, Medtronic, Inc., Role: Site PI, "Harmony Transcatheter Pulmonary Valve Post-Approval (PAS2) Study"

UM-5500018955, Zampi (PI), 8/1/20 – 7/31/24, “Neurocognitive Function of Adolescents and Young Adults with Repaired Complex Congenital Heart Disease after Recent Cardiac Re-interventions: A Pilot Study”

U24HL135691, 4/18/22 – 12/31/24, “Comparison of Methods of Pulmonary Blood Flow Augmentation in Neonates: Shunt versus Stent (The COMPASS Trial)”

U24HL135691, 11/1/22 – 11/1/25, “Use of Oxandrolone to Promote Growth in Infants with Hypoplastic Left Heart Syndrome: A Phase I/II Pilot Study”

ASCENT-ASD121,  3/14/22 – 3/14/27, “Evaluation of the safety and efficacy of the reSept ASD Occluder to treat patients with clinically significant secundum atrial septal defect (ASCENT ASD Study)”