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Desiree Noel Wagner Neville, MD

  • Assistant Professor of Pediatrics

Neville is an Assistant Professor of Pediatric Emergency Medicine and is the Associate Director of Emergency point-of-care ultrasound (POCUS). She has built a body of work that includes educational curricula and innovative teaching platforms that have advanced the POCUS education both within her division and throughout UPMC Children’s Hospital of Pittsburgh. She serves as Director of the Pediatric Resident POCUS elective. She also facilitates simulation-based education. Neville's research focus is on Pediatric Lyme Disease. She developed the UPMC Children’s Hospital of Pittsburgh Lyme disease Clinical Effectiveness Guideline that is used throughout the hospital system. She serves as the site PI for Pedi Lyme Net, a research collaborative of Emergency Medicine departments in Lyme endemic areas. Through this collaboration she has disseminated their work in publications and presentations at national meetings, and they have created a Pediatric Lyme Disease Biobank repository housed at Boston Children’s Hospital.

Professional and Scientific Society Memberships

  • American Academy of Pediatrics: Section on Emergency Medicine
    • SOEM Special Interest Group

Education & Training

  • BS, Bioengineering, Pennsylvania State University, 2006
  • MD, University of Virginia, 2010
  • Residency in Pediatrics, Children's Hospital of Pittsburgh, 2010-2013
  • Fellowship in Pediatric Emergency Medicine, Children's Hospital of Pittsburgh, 2013-2016

Selected Publications

Liang S, Fu C, Wagner D, Guo H, Zhan D, Dong C, Long M. Two-dimensional kinetics of beta 2-integrin and ICAM-1 bindings between neutrophils and melanoma cells in a shear flow. Am J Physiol Cell Physiol. 2008 Mar; 294(3):C743-53. PMID: 18199704   

Liang S, Slattery MJ, Wagner D, Simon SI, Dong C.  Hydrodynamic shear rate regulates melanoma-leukocyte aggregation, melanoma adhesion to the endothelium, and subsequent extravasation. Ann Biomed Eng. 2008 Apr; 36(4):661-71. PMID: 18253835

Neville DN, Hayes KR, Ivan Y, McDowell ER, Pitetti RD. Double-blind randomized controlled trial of intranasal dexmedetomidine versus intranasal midazolam as anxiolysis prior to pediatric laceration repair in the emergency department. Acad Emerg Med. 2016 Aug; 23(8):910-7. PMID: 27129606

Garro A, Bennett J, Balamuth F, Levas MN, Neville D, Branda JC, Maulden AB, Lantos PM, Nigrovic LE; Pedi Lyme Net. Positive Two-tiered Lyme Disease Serology is Uncommon in Asymptomatic Children Living in Endemic Areas of the U.S. Pediatr Infect Dis J. 2019 May;38(5):e105-e107. PMID: 30067595

Nigrovic LE, Lipsett SC, Molins CR, Wormser GP, Bennett JE, Garro AC, Levas MN, Balamuth F, Neville D, Lingampalli N, Robinson WH, Branda JA. Higher C6 enzyme immunoassay index values correlate with a diagnosis of noncutaneous Lyme disease. 2019 Jun;94(2):160-164. PMID: 30642722

Maulden AB, Garro AC, Balamuth F, Levas MN, Bennett JE, Neville DN, Branda JA, Nigrovic LE; for Pedi Lyme Net. Two-Tier Lyme Disease Serology Test Results Can Vary According to the Specific First-Tier Test Used. J Pediatric Infect Dis Soc. 2019 Feb 22. PMID: 30793167

Nigrovic LE, Neville DN, Balamuth F, Bennett JE, Levas MN, Garro AC for Pedi Lyme Net. A minority of children with Lyme disease recall a preceding tick bite. Ticks Tick Borne Dis. 2019 Apr;10(3):694-696. PMID: 30853264

Nigrovic LE, Lewander DP, Balamuth F, Neville DN, Levas MN, Bennett JE, Garro A. The Lyme Disease Polymerase Chain Reaction Test Has Low Sensitivity. Vector Borne Zoonotic Dis. 2019 Dec 10. PMID: 31821110

Nigrovic LE, Bennett JE, Balamuth F, Levas MN, Neville D, Lyons TW, Branda JA, Maulden AB, Lewander D, Garro A; PEDI LYME NET. Diagnostic Performance of C6 Enzyme Immunoassay for Lyme Arthritis. Pediatrics. 2020 Jan;145(1) PMID: 31836615

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