Eva M. Szigethy, MD, PhD

  • Professor of Psychiatry, Pediatrics, and Medicine

Administrative Assistant: Kate Saucier

Eva M Szigethy, MD, PhD, is Professor of Psychiatry, Pediatrics and Medicine at the University of Pittsburgh. Dr. Szigethy is co-founder and Director of the IBD Total Care Program and was instrumental in creating the Program for Gut-Brain Health for patients with motility disorders. She has conducted several studies funded by NIMH and the NIH Director’s Innovator Award to develop and show efficacy of CBT for depression and physical (pain, inflammation) outcomes for patients with IBD. Recently, she has focused her clinical and research interests on designing integrated medical-psychiatric models of care for patients with chronic disease. Dr. Szigethy is a Co-PI on a $6 million PCORI grant evaluating how behavioral technical innovation can enhance integrated care delivery using patients with inflammatory bowel disease and behavioral symptoms as a model. Dr. Szigethy has been the behavioral technology advisor for UPMC Enterprises, the venture capital arm of UPMC. She is also helping develop behavioral technology and digital tools and telemedicine to enhance care delivery for adolescents and adults across the University of Pittsburgh Medical Center (UPMC) system in her leadership role as Behavioral Director within the Chief Medical and Scientific Office. 

Professional and Scientific Society Memberships

  • American Psychiatric Association (APA), 1993-Present
  • American Academy of Child and Adolescent Psychiatry (AACAP), 1997-Present
  • Crohn’s and Colitis Foundation of America, 2002-Present
  • American Society of Clinical Hypnosis (ASCH), 2007-Present
  • American Academy of Psychoanalysis and Dynamic Psychiatry (AAPDP), 2009-Present
  • American Psychosomatic Society (APS), 2012-Present
  • American College of Gastroenterology (ACG) Fellow Status, 2014-Present
  • American Gastroenterology Association (AGA), 2015- Present
  • Crohn’s and Colitis UK Steering Committee Member, 2019-Present

Education & Training

  • BA, Neuropsychology, Princeton University, 1985
  • PhD, Neuroanatomy, McGill University, 1989
  • MD, University of Rochester, 1993
  • MS, Medical Sciences, Harvard Medical School, 2003
  • Residency in General Psychiatry, Case Western Reserve University, 1993-1997
  • Residency in Child and Adolescent Psychiatry, Case Western Reserve University, 1997-1998
  • Residency in Child and Adolescent Psychiatry, Children's Hospital of Boston, 1998-1999
  • Six-Month Training in PASCET Cognitive Behavioral Therapy, Children's Hospital of Boston, 1999
  • Clinical Research Training Program, Auditing Participant, Children's Hospital of Boston, 1999-2001
  • Advanced Training in Clinical Hypnosis, University of Pittsburgh Medical Center, 2007
  • American Society of Clinical Hypnosis Certification, 2009
  • Visiting Scholars Program, UNC Center for Functional GI & Motility Disorders, 2011
  • Opioid Risk Evaluation and Mitigation Strategies Training, Pennsylvania Medical Society, University of Pittsburgh Medical Center

Selected Publications

Regueiro M, Click B, Anderson A, Shrank W, Kogan J, McAnallen S, Szigethy E.  Reduced unplanned care and disease activity and increased quality of life after patient enrollment in an inflammatory bowel disease medical home.  Clin Gastroenterol Hepatol. 2018; S1542-3565(18)30343-4.  Doi: 10.1016/j.cgh.2018.04.007  PMID: 29654918

Click B, Anderson AM, Ramos Rivers C, Koutroubakis IE, Hashash JG, Dunn MA, Schwartz M, Swoger J, Barrie A, Szigethy E, Regueiro M, Schoen RE, Binion DG.  Telephone encounters predict future high financial expenditures in inflammatory bowel disease patients: A 3 year prospective observational study.  J Clin Gastroenterol. 2018; 52:319-325.  PMID: 28452828

Click BH, Greer JB, Regueiro MD, Hartman DJ, Davis PL, Siegel CA, Herfath HH, Rosh JR, Shah SA, Koltun WA, Binion DG, Baidoo L, Szigethy E. IBD LIV Series- Case 7: The Brain-Gut Connection and the Importance of Integrated Care in IBD.  Inflamm Bowel Dis.  2017; 23:681-694.

Szigethy E, Solano F, Wallace M, Perry D, Morell L, Kathyrn S, Jones MB, Oser M. Assessing feasibility and effectiveness of a mobile cognitive behavioral program with integrated coaching for anxious adults in primary care: Protocol for a mixed method parallel group design.  BMJ Open 2018 January 13. 8(1) PMID 29331971

Knisely M, Hashash J, Wallace M, Mcauliff K, Strassburger M, Keljo D, Regueiro M, Binion D, Germain A, Szigethy E  Serial open trial of a brief behavioral intervention and bupropion for sleep disturbance and fatigue in adolescents and young adults with Crohn’s disease. Inflamm Bowel Dis, (submitted, 2017)

Yu, JS, Szigethy E, Wallace M, Solano F, Oser M.  Implementation of a Guided Digital Cognitive Behavioral Program for Anxiety in Primary Care: Preliminary Findings of Engagement and Effectiveness.  J Telemedicine and e-Health. February 26, 2018. PMID: 29480752

Oser M, Wallace M, Solano F, Szigethy E. A Propensity Matched Controlled Trial of a Guided Digital Behavioral Program for Anxiety in Primary Care. Journal of Medical Internet Research. 2019 Apr 4;6(4):e11981. doi: 10.2196/11981

Szigethy E, Wallace M, Regueiro M, Oser M. Improving Quality of Care with a Digital Behavioral Program in IBD Specialty Medical Home. (in preparation, 2019)

Knisely, M.R., Conley, Y.P., & Szigethy, E.M. (accepted/in press). Cytokine genetic variants and health-related quality of life in Crohn’s disease: An exploratory study. Biological Research for Nursing. 2019; 21(5):109980041986090 

Szigethy E, Murphy SM, Ehrlick O, Engel-Nitz, NM, Heller C, Henrichsen K, Lawton R, Meadows P, Allen JI.  Mental Health Costs of Inflammatory Bowel Diseases. Inflamm Bowel Dis. 2020 (accepted).

Full Publication List via NIH PubMed »

Research Grants

Szigethy (Co-I) Consortium for the Study of Pancreatitis, Pittsburgh Clinical Center (Whitcomb D, PI)  U01-DK108306 2015-2020. This grant is aimed to develop an integrated clinical center core processes to facilitate data and bio-sample management, to maximize communication and to evaluate new technologies. 2% effort.

Szigethy E (PI) PCORI Grant Specialty Medical Homes to Improve Outcomes for Patients with IBD and Behavioral Health Conditions, February 2019 – July 2023. Direct costs $ 4,478,571  20% effort.

Szigethy E (PI) Multimodal Screening for Depression. Create a new screen utilizing artificial intelligence to identify behavioral markers of depression within vocal and facial channels.

Szigethy E (PI) Coping Behaviors of African Americans with Inflammatory Bowel Disease. This study will examine what struggles and successes African Americans encounter related to their IBD, and what concerns they may have related to their quality of life.

Szigethy E (Co-I) The effect of cannabidiol on the severity of persistent post-concussion symptoms UPMC is being contracted by commercial company to develop and oversee the mental health screening and neurocognitive testing, as well as mental health assessment and delivery of mobile health interventions for retired national hockey players who screen positive for depression, anxiety, PTSD, and/or addiction.  January, 2019- September 2020.  Direct Costs $ 1,198,815.94 20% effort.

Szigethy E (Co-I) Leveraging Technology to Treat Anxiety Disorders in Community Pediatrics. Pending