Frederico Xavier, MD, MS

  • Assistant Professor of Pediatrics
  • Associate Clinical Director, Hemophilia Center of Western Pennsylvania

Administrative Assistant: Ashley Kosarich

Dr. Xavier joined the University of Pittsburgh in July 2017 as Assistant Professor in the Department of Pediatrics, Division of Pediatric Hematology/Oncology. Dr. Xavier also holds an appointment as Associate Clinical Director at the Hemophilia Center of Western Pennsylvania.

Dr. Xavier completed his medical school, pediatric residency and fellowship training in Brazil. He then completed pediatric residency in NY, pediatric hematology/oncology fellowship at St. Jude Children’s Hospital, Memphis, TN, and then a pediatric hemostasis fellowship at the Hospital for Sick Children, Toronto, Ontario, Canada in 2011. After that he completed a Masters degree in Clinical Research at the Indiana University-Purdue University Indianapolis in 2014.

Dr. Xavier has published peer-reviewed articles and book chapters in the field of pediatric hemostasis, and is currently awarded with a research grant to study inflammation in Hemophilia. Dr. Xavier also sits in the Newborn Screening and Follow-up Technical Advisory Board for the Pennsylvania Department of Health.

Selected Publications

PT. Ebbert, F. Xavier, CD. Seaman, MV. Ragni, Emicizumab Prophylaxis in Patients with Hemophilia A with and without Inhibitors in Haemophilia.Haemophilia 2019 November 11.

J. Lapinsky, L. Maurer, MV Ragni, C. McSeah, J. Cooper, F. Xavier, Unsuspected Lyme Disease Presenting as Refractory Hemophilic Hemarthrosis. Haemophilia. 2019 July 29.

WJ Ares, DA Tonetti, S Greene, MS Sharma, F. Xavier, BT Jankowitz, A Jadhav. Pipeline Embolization of an Infectious Basilar Artery Aneurysm in a 2-Year-Old Child: Case Report, Discussion of the Literature and Perioperative Considerations. Oper Neurosurg (Hagerstown). 2019 Jan 23. doi: 10.1093/ons/opz002. [Epub ahead of print]PMID:30690548

J. Cashell, GM. Smink, K. Helm, F. Xavier, Kaposiform hemangioendothelioma with Kasabach-Merritt phenomenon in an infant: Successful treatment with prednisolone, vincristine,and addition of sirolimus. Pediatr Blood Cancer. 2018 Aug 1.

F. Xavier, P. Komvilaisak, S.Williams, A.V. Kulkarni , G. deVeber, M.D. Moharir.Anticoagulant therapy in head injury-associated Cerebral Sinovenous Thrombosis in Children. Pediatric Blood and Cancer, 2014 Nov;61(11):2037-42

M.Chan, A. Leckie, F. Xavier, E. Uleryk, S. Tadros, V. Blanchette, A. Doria. MR imaging as a tool for evaluating hemophilic arthropathy in children, asystematic review and recommendations. Haemophilia. 2013, 19 (6) 324-34.

F. Xavier, A. Shapiro. Miscellaneous rare bleeding disorders. In: Textbook of Hemophilia. Blackwell publishing 2013. ISBN: 978-1-118-39824-1.

F. Xavier, V. Blanchette. Rare congenital factor deficiencies in childhood. In: SickKidshandbook for pediatric hemostasis and thrombosis. Basel, Karger, 2013, pp 90–104 (DOI:10.1159/000346947).

F. Xavier, N. Zhang, A. Mohanta, P.Hilliard, C. Man, D. Drossmann, A. Stain, V. Blanchette, A. Doria. Sonography for assessment of elbows in hemophilic children: A systematic protocol.Rheumatol Curr Res. 2012, S2 P.

Favaro, H.D. Downey, F. Mingozzi, F. Xavier, J.F. Wright, K.A. High, V.R. Arruda. Interaction of Host and Vector-Dependent Factors in Determining the Risk of Germline Transmission of AAV Vectors. Molecular Therapy, 2007;15(1). [American Society of GeneTherapy] F. Xavier, “Basis of Cellular and Molecular Medicine”, Federal University of Sao Paulo (Unifesp) – School of Medicine, July 2003.

F. Xavier, A.M.F. Magalhaes, J.A.R. Gontijo. Effect of nitric oxid synthase on blood pressure and renal sodium handling in renal denervated rats. Brazilian Journa lof Medical and Biological Research, 2000;(33):347-354.

Full Publication List via NIH PubMed

Academic and Research Interests

Pediatric Thrombosis and Hemostasis Vascular Anomalies

Research Grants

2018-Current Awarded HRSA research grant (97$K) for two years project – Inflammasome and Hemophilia