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Jessica D. Daley, MD
- Assistant Professor of Pediatrics
Dr. Daley is a junior faculty physician scientist in the Division of Pediatric Hematology-Oncology with a research focus on the immunobiology of pediatric sarcomas. Her current research focuses on Ewing sarcoma and understanding the tumor immune microenvironment of this rare, aggressive adolescent and young adult cancer. In addition to her translational research in Ewing sarcoma, Dr. Daley also helps to lead the Adolescent and Young Adult oncology working group, a shared program between UPMC Children's and Hillman Cancer Center aiming to improve the care of adolescent and young adult patients with cancer at our institution.
Education & Training
- BA, Hamilton College, 2009
- MD, Tufts University School of Medicine, 2015
- Residency in Pediatrics, Hasbro Children's Hospital, 2015-2018
- Fellowship in Pediatric Hematology- Oncology, UPMC Children's Hospital of Pittsburgh, 2019-2022
Selected Publications
Dietz JA, Johnson KL, Massingham LJ, Schaper J, Horlitz M, Cowan J, Bianchi DW. Comparison of extraction techniques for amniotic fluid supernatant demonstrating improved yield of cell-free fetal RNA. Prenat Diagn. 2011;31(6):598-9.
Dietz JA, Johnson KL, Wick HC, Bianchi DW, Maron JL. Optimal techniques for mRNA extraction from neonatal salivary supernatant. Neonatology. 2012;101(1):55-60.
Maron JL, Johnson KL, Dietz JA, Chen ML, Bianchi DW. Neuropeptide Y2 receptor (NPY2R) expression in saliva predicts feeding immaturity in the premature neonate. PLoS One. 2012;7(5):e37870.
Maron JL, Dietz JA, Parkin C, Johnson KL, Bianchi DW. Performing discovery-driven neonatal research by transcriptomic analysis of routinely discarded biofluids. J Matern Fetal Neonatal Med. 2012;25(12):2507-11.
Segal JE, Daley JD, Barnum JL, Salgado CM, Reyes-Mugica M, Schneider C, Gumus S, Thakrar D, Allen SW, Canna SW. Systemic and Nodular Hyperinflammation in a Patient with Refractory Familial Hemophagocytic Lymphohistiocytosis 2. J Clin Immunol. 2021 Feb 11.
Maurer LM, Daley JD, Mukherjee E, Venier RE, Julian CM, Bailey NG, Jacobs MF, Kumar-Sinha C, Raphael H, Periyapatna N, Weiss K, Janeway KA, Mody R, Lucas PC, McAllister-Lucas LM, Bailey KM. BRCA1-Associated RING Domain-1 (BARD1) loss and GBP1 expression enhance sensitivity to DNA Damage in Ewing sarcoma. Cancer Res Commun. 2022; 2(4): 220-232.
Daley JD, Williams N, Salgado CM, Schultz C, Meade J, Ozolek J, Lindsey B, Bailey KM. Cutaneous Ewing Sarcoma Presenting as a Second Primary Malignancy in a Child. J Pediatr Hematol Oncol. 2022 Apr 14. doi: 10.1097/MPH.0000000000002457. Epub ahead of print. PMID: 35426856.
Cillo AR, Mukherjee E, Bailey NG, Onkar S, Daley JD, Salgado C, Li X, Li D, Ranganathan S, Burgess M, Sembrat J, Weiss K, Watters R, Bruno TC, Vignali DAA, Bailey KM. Ewing sarcoma and osteosarcoma have distinct immune signatures and intercellular communication networks. Clin Cancer Res. 2022 Sep 8:CCR-22-1471. doi: 10.1158/1078-0432.CCR-22-1471. Epub ahead of print. PMID: 36074145.
Daley JD, Olson AC, Bailey KM. Harnessing immunomodulation during DNA damage in Ewing sarcoma. Front Oncol. 2022;12:1048705. doi: 10.3389/fonc.2022.1048705. eCollection 2022. Review. PubMed PMID: 36483025; PubMed Central PMCID: PMC9722957.
Daley J, Halligan K, Howrie D, Salgado CM, Superdock A, Friehling E, Bailey KM. Successful Treatment of Patient With Ewing Sarcoma in the Setting of Inherited Cholestatic Liver Disease. J Pediatr Hematol Oncol. 2023 Jan 12;. doi: 10.1097/MPH.0000000000002623. PMID: 36728269.