Jessie L. Barnum, MD

  • Assistant Professor of Pediatrics
  • Director, Advance Practice Provider Fellowship

Administrative Assistant: Karan Pruszynski

Barnum is a Pediatric Hematologist/Oncologist who practices in the Division of Blood and Marrow Transplantation and Cellular Therapies. She is certified in Pediatrics and Pediatric Hematology and Oncology by the American Board of Pediatrics. She is an Assistant Professor of Pediatrics at the University of Pittsburgh School of Medicine. She received her medical degree from Creighton University School of Medicine and completed her Pediatrics residency at Stanford University, followed by her fellowship in Pediatric Hematology/Oncology/Blood and Marrow Transplantation at the University of Minnesota and fellowship in Blood and Marrow Transplantation and Cellular Therapies at St. Jude Children’s Research Hospital. She is currently enrolled in the Institute for Clinical Research Education program through the Clinical and Translational Science Institute of the University of Pittsburgh, pursuing a Master’s in the clinical trials track. Dr. Barnum’s clinical interests include immunodeficiency, autoimmunity and immune dysregulation, bone marrow failure, and infections in immunocompromised hosts. She has published in peer-reviewed journals and has open clinical trials in these areas. She is a member of the American Society of Hematology, the American Society of Pediatric Hematology/Oncology, American Society of Transplantation and Cellular Therapies, and the Transplantation Society. She serves on the Primary Immune Deficiency Treatment Consortium, North American Immuno-Hematology Clinical Education and Research Consortium steering committee and the board of the North American Pediatric Aplastic Anemia Consortium. Dr. Barnum lives in the north hills with her husband and two daughters, and enjoys spending time outdoors.

Professional and Scientific Society Memberships

  • American Society for Blood and Marrow Transplantation, 2012-Present
  • American Society of Hematology, 2012-Present
  • American Society of Pediatric Hematology/Oncology, 2012-Present
  • Children’s Oncology Group, 2012-Present
  • The Transplantation Society, 2017-Present
  • Primary Immune Deficiency Treatment Consortium, 2017-Present

Education & Training

  • BA, Natural Science, Concordia University, 2002
  • MD, Creighton University School of Medicine, 2009
  • Residency in Pediatrics, Lucile Packard Children's Hospital, Stanford University Medical Center, 2009-2012
  • Fellowship in Pediatric Hematology-Oncology and Blood and Marrow Transplant, University of Minnesota Masonic Children's Hospital, 2012-2015
  • Fellowship in Bone Marrow Transplant and Cellular Therapies, St. Jude Children's Research Hospital, 2015-2016

Selected Publications

Rowan CM, Gertz SJ, Zinter MS, Moffet J, Bajwa RPS, Barnum JL, Kong M. A multicenter investigation of respiratory syncytial viral infection after hematopoietic cell transplantation in children. Transpl Infect Dis 2018 Mar 23:e12882. PubMed PMID 29573141. 

Pennell CA, Barnum JL, McDonald-Hyman CS, Panoskaltsis-Mortari A, Riddle MJ, Xiong Z, Loschi M, Govindarajan T, Campbell HM, Storlie MD, Refaeli Y, Furlan S, Jensen MC, Kean LS, Miller JS, Tolar J, Osborn MJ, Blazar BR. Human CD19-targeted mouse T-cells induce B-cell aplasia and toxicity in human CD19 transgenic mice. Mol Ther. 2018 Jun 6;26(6):1423-1434. doi: 10.1016/j.ymthe.2018.04.006. Epub 2018 Apr 7. PubMed PMID: 29735365

Stanczak H, Nastasi N, Helmick D, Chen X, Windreich R, Barnum J, Carella B, Byersdorfer B, Donnenberg A, Moor L, Szabolcs P. Processing and CD3+/CD19+ depletion of cadaveric vertebral bone marrow for primary immunodeficiency patients undergoing sequential bilateral orthotopic lung transplant (BOLT) and bone marrow transplant (BMT). Cytotherapy. 2019 May Vol 21, Issue 5, Supplement pages e3-e4.

Barnum J, VanderLugt M, Soltys K, Szabolcs P, Bond G, Ganoza A, Mazariegos GV. Long term follow up of cord blood followed by intestinal transplant in patient with immunodeficiency and intestinal failure. June 2019. Transplantation 103:S85. DOI: 10.1097/01.tp.0000575908.51560.96

McDyer J, Mcintyre S, Chen X, Koshy R, Popescu J, Stanczak HM, Hannan S, Barnum J, Morrell M, Pilewski JM, Kurland G, Gerardo Sanchez P, D’Cunha J, Szabolcs P. Combined bilateral lung transplantation and bone marrow transplantation in select patients with end-stage lung disease: a potential for long-term allograft tolerance induction. September 2019, Chest 156(4):A1097-A1098. DOI: 10.1016/j.chest.2019.08.1008

Burk CM, Coffey KE, Mace EM, Bostwick BL, Chinn IK, Coban-Akdemir ZH, Jhangiani SN, Lupski JR, Ortiz D, Barnum, JL, Allen SW, Robertson LM, Orange JS, Chong HJ. Immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome with NK dysfunction and EBV-driven malignancy treated with stem cell transplantation. J Allergy Clin Immunol Pract 2020 Mar;8(3):1103-1106.e3. doi: 10.1016/j.jaip.2019.08.040. Epub 2019 Sep 11. PubMed PMID: 31520839

Burroughs L, Petrovic A, Brazauskas R, Liu Z, Griffith LM, Ochs HD, Bleesing JJ, Edwards S, Dvorak, CC, Chaudhury S, Prockop SE, Quinones R, Goldman FD, Quigg TC, Chandrakasan S, Smith AR, Parikh S, Dávila Saldaña BJ, Thakar MS, Phelan R, Shenoy S, Forbes LR, Martinez C, Chellapandian D, Shereck E, Miller HK, Kapoor N, Barnum JL, Chong H, Shyr DC, Chen K, Abu-Arja R, Shah AJ, Weinacht KG, Moore TB, Joshi A, DeSantes KB, Gillio AP, Cuvelier GDE, Keller MD, Rozmus J, Torgerson T, Pulsipher MA, Haddad E, Sullivan KE, Logan BR, Kohn DB, Puck JM, Notarangelo LD, Pai SY, Rawlings DJ, Cowan MJ. Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich Syndrome: A PIDTC report. Blood. 2020 Apr 8. pii: blood.2019002939. doi: 10.1182/blood.2019002939. [Epub ahead of print] PubMed PMID: 32268350

Vanderlugt MT, Chen X, Escolar ML, Carella BA, Barnum JL, Windreich RM, Hill MJ, Marsh RA, Stanczak MT, Stenger EO, Szabolcs P. Reduced-intensity single-unit unrelated cord blood transplant with optional immune boost for non-malignant disorders, Blood Advances, manuscript #ADV-2020-001940R1, June 2020

Dorsey M, Wright N, Chiamowitz N, Davila B, Keller M, Thakar M, Shah A, Abu-Arja R, Andolina J, Aquino V, Barnum JL, Bednarski J, Bhatia M, Bonilla F, Butte M, Chandra S, Chandrakasan S, Chaudhury S, Chen K, Chong H, Cuveiler G, Dalal J, DeFelice M, DeSantes K, Forbes L, Gilio A, Goldman F, Joshni A, Kapoor N, Knutsen AP, Kobrynski L, Lieberman J, Oshrine B, Patel K, Prockop S, Quigg T, Quinones R, Grazia Roncorolo M, Schultz K, Seroogy C, Shyr D, Siegel S, Smith A, Torgeson TR, Vanderlugt M, Yu L, Cowan MJ, Buckley RH, Dvorack CC, Griffith L, Haddad E, Kohn DB, Logan B, Notarangelo N, Pai SY, Puck J, Pulsipher M, Heimall J. Infections in newborn SCID patients: current status of isolation, viral infection screening and prophylaxis in PIDTC Centers. Journal of Clinical Immunology, Epub ahead of print. 2020 Oct 2. doi: 10.1007/s10875-020-00865-9. PMID: 33006109

Segal JE, Daley J, Barnum JL, Salgado C,  Reyes-Mugica M, Schneider C, Gumus S, Thakrar D, Allen SW, Canna SW. Evolving hyperinflammation and Lung and Kidney Nodules in Refractory Type 2 Familial Hemophagocytic Lymphohistiocytosis, Journal of Clinical Immunology, Epub ahead of print. 2021 February.

 

Academic and Research Interests

  • immunology
  • transplant
  • bone marrow failure
  • immunodeficiency
  • immunocompromised hosts