- Home
- About Us
- Divisions
- Adolescent and Young Adult Medicine
- Allergy and Immunology
- Blood and Marrow Transplantation and Cellular Therapies
- Cardiology
- Child Advocacy
- Emergency Medicine
- Endocrinology
- Gastroenterology, Hepatology and Nutrition
- General Academic Pediatrics
- Genetic and Genomic Medicine
- Health Informatics
- Hematology-Oncology
- Infectious Diseases
- Nephrology
- Neurology and Child Development
- Newborn Medicine
- Paul C. Gaffney Division of Pediatric Hospital Medicine
- Pulmonology
- Rheumatology
- Centers & Institutes
- Center for Pediatric Research in Obesity and Metabolism
- Center for Rare Disease Therapy
- Children's Neuroscience Institute
- Cystic Fibrosis Research Center
- Institute for Infection, Inflammation, and Immunity in Children
- Pediatric Asthma Center
- Pediatric Institute for Heart Regeneration and Therapeutics
- Richard King Mellon Foundation Institute for Pediatric Research
- Pittsburgh Vaccine Trials Unit
- The Pittsburgh Study
- Research
- Diversity
- Education
- Faculty Affairs
- News
- People
- Podcasts
Jie Lu
- Lab Manager
Education & Training
- BA, Hunan Medical School, China
Selected Publications
1, Inhibition of Hepatocellular Carcinoma by Metabolic Normalization Wang H, Lu J, Dolezal J, Kulkarni S, Zhang W, Chen A, Gorka J, Mandel JA,Prochownik EV. PLoS One. 2019 Jun 26;14(6):e0218186. doi: 10.1371/journal.pone.0218186. eCollection 2019. PMID: 31242205
2, β-CateninMutations as Determinants of Hepatoblastoma Phenotypes in Mice Zhang W, Meyfeldt J, Wang H, Kulkarni S, Lu J, Mandel JA, Marburger B, Liu Y,Gorka JE, Ranganathan S, Prochownik EV. J Biol Chem. 2019 Nov 15;294(46):17524-17542. doi: 10.1074/jbc.RA119.009979. Epub 2019 Oct 9. PMID:31597698
3, Metabolic and Oncogenic Adaptations to Pyruvate Dehydrogenase Inactivation in Fibroblasts Wang H, Lu J, Kulkarni S, Zhang W, GorkaJE, Mandel JA, Goetzman ES, Prochownik EV. J Biol Chem. 2019 Apr 5;294(14):5466-5486. doi: 10.1074/jbc.RA118.005200. Epub 2019 Feb 12. PMID:30755479
4, Myc and ChREBP Transcription Factors Cooperatively Regulate Normal and Neoplastic Hepatocyte Proliferation in Mice Wang H, DolezalJM, Kulkarni S, Lu J, Mandel J, Jackson LE, Alencastro F, Duncan AW, Prochownik EV. J Biol Chem. 2018 Sep 21;293(38):14740-14757. doi:10.1074/jbc.RA118.004099. Epub 2018 Aug 7. PMID: 30087120
5, Ribosomopathy-like Properties of Murine and Human Cancers Kulkarni S, DolezalJM, Wang H, Jackson L, Lu J, Frodey BP, Dosunmu-Ogunbi A, Li Y, Fromherz M, Kang A, Santana-Santos L, Benos PV, Prochownik EV. PLoS One.2017 Aug 18;12(8):e0182705. doi: 10.1371/journal.pone.0182705. eCollection 2017. PMID: 28820908
6, Sequential Adaptive Changes in a c-Myc-drivenModel of Hepatocellular Carcinoma Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K,Byersdorfer CA, Prochownik EV. J Biol Chem. 2017 Jun 16;292(24):10068-10086. doi: 10.1074/jbc.M117.782052. Epub 2017 Apr 21. PMID: 28432125
Research Interest Summary
Liver Cancer