Michelle Roe, MD

  • Resident, PGY-2

Michelle was born in Los Angeles and raised in the suburbs of Chicago. She went to the University of Connecticut for her B.S. in Physiology & Neurobiology, where she found her love of research beginning in her freshman year. Michelle's close friend and family member was diagnosed with recurrent sarcoma during college, which inspired Michelle to spend more time learning about sarcoma and trying to find ways she might make any difference for patients suffering with this malignancy. After graduating, Michelle went to MD Anderson Cancer Center in Houston, TX, where she had an internship for a few months until she was hired to work as a research assistant in the sarcoma research laboratory of Dr. Keila Torres. After two years, Michelle went to medical school at the University of South Florida, where she continued to perform research, but with a focus on bioinformatics in the laboratory of Dr. George Blanck. Michelle Applied her team's research techniques to sarcoma wherever possible. Michelle was certain that she wanted to work in the field of Oncology prior to beginning medical school, but she was still undecided on how she would apply her passion for Oncology clinically. After her rotations in Pediatrics, she was certain that Pediatric Hematology-Oncology would be the best fit for her. Michelle loves taking care of children and appreciates the fun, variety, and even challenges that each patient presents. Michelle looks forward to developing meaningful relationships with her patients and their families as a resident of pediatrics, and for the rest of her career. Michelle chose UPMC Children's Hospital of Pittsburgh for her education in Pediatrics because of their strong research opportunities, reputation for providing a high level of patient care that is evidence-based while maintaining patient dignity, as well as the family-feel of the program despite its relatively large size.

Hometown

Barrington, IL

Medical School

University of South Florida Morsani College of Medicine

Professional and Scientific Society Memberships

  • Robert A. Good Honor Scoiety, 2021 - Present

Education & Training

  • BS, University of Connecticut, 2016
  • MD, USF Morsani College of Medicine, 2022

Selected Publications

Chopra A, Bond MJ, Bleiler M, Yeagley [Roe] M, Wright D, Giardina C . (2016, Apr). Efficient Activation of Apoptotic Signaling during Mitotic Arrest with AK301. PLoS One, 11(4), PMID: 27097159. 

McBride et al.. (2018, May). The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma. Cancer Cell, 33(6), 1128–1141. PMID: 29861296.

Arturo JF, Chobrutskiy BI, Yeagley [Roe] M, Patel DN, Falasiri S, Patel JS, Blanck G . (2019, Nov). Electrostatic complementarity of B-cell receptor CDR3s and TP53-mutant amino acids in breast cancer is associated with increased disease-free survival rates. Cell Mol Immunol, 17(7), 776-778. PMID: 31729463. 

Chobrutskiy BI, Yeagley [Roe] M, Diviney A, Zaman S, Gozlan EC, Tipping P, Koohestani DM, Roca AM, Blanck G . (2019, Dec). A scoring system for the electrostatic complementarities of T-cell receptors and cancer-mutant amino acids: Multi-cancer analyses of associated survival rates. Immunology, 159(4), 373-383. PMID: 31821535. 

Chobrutskiy BI, Yeagley [Roe] M, Tipping P, Zaman S, Diviney A, Patel DN, Falasiri S, Uversky VN, Blanck G. (2020, Feb). Chemical complementarity between immune receptor CDR3s and IDH1 mutants correlates with increased survival for lower grade glioma. Oncogene, 39(8), 1773–1783.

Arndt MF, Koohestani DM, Chobrutskiy BI, Mihyu MM, Diaz M, Gozlan EC, Yeagley [Roe] M, Zaman S, Roca AM, Blanck G . (2020, Sep). TRBV and TRBJ usage, when paired with specific HLA alleles, associates with distinct head and neck cancer survival rates. Hum Immunol, 81(12), 692-696. PMID: 32950267. 

Yeagley [Roe] M, Chobrutskiy BI, Gozlan EC, Medikonda N, Patel DN, Falasiri S, Callahan BM, Huda T, Blanck G . (2021, Feb). Electrostatic Complementarity of T-Cell Receptor-Alpha CDR3 Domains and Mutant Amino Acids Is Associated with Better Survival Rates for Sarcomas. Pediatric Hematology and Oncology, 38(3), 251-264. PMID: 33616477. 

Chobrutskiy B, Chobrutskiy A, Zaman S, Yeagley [Roe] M, Huda T, Blanck G. (2021, Jul). High-throughput, sliding-window algorithm for assessing chemical complementarity between immune receptor CDR3 domains and cancer mutant peptides: TRG-PIK3CA interactions and breast cancer. Molecular Immunology, 135( ), 247-253. PMID: 33933816.