Patricia K. Crumrine, MD

  • Professor of Pediatrics

Crumrine is Professor of Pediatrics at the University of Pittsburgh School of Medicine in the Clinical Track and Educator Track, and Attending Child Neurologist/Epileptologist at UPMC Children’s Hospital of Pittsburgh.  Her career there has been as the electroencephalographer and epileptologist, and has included director of EEG and Epilepsy from 1975-2008 and director of the Child Neurology Residency Program from 2006-2013.  

Her clinical research has been primarily in the clinical trials of new antiepileptic drugs. These have included  the site PI for the following multicenter NINDS funded studies including ( Changes in Clearance of Antiepileptic Drugs During Puberty 1996-1999; Childhood Absence Seizure Study 2003-2013; and the Epilepsy Phenonome, Genome Study, 2010-2012) as well as the site PI for a number of pharmaceutical sponsored clinical drug trials (cinromide, lamotrigine, vigabatrin).

Crumrine has been active in the American Academy of Pediatrics, serving on their Scientific Selection Committee from 1989-1995; American Board of Psychiatry and Neurology, serving as an examiner from 1978-2008, on several of the exam writing committees, and as a director on the Board from 2006-2013. She also served as a Councillor, Secretary-Treasurer, and Newsletter editor for the Child Neurology Society; two separate terms on the Professional Advisory Board of the Epilepsy Foundation of America; Counsellor for the Clinical Neurophysiology Society from 199-2002; Member 2006-2013 and Chair for the Neurology Residency Review Committee 2011-2013 for the ACGME. She currently serve on several committees for the American Academy of Neurology (Task Force on Neurologist Burnout), Member Research Subcommittee, Member Retention Committee and became a fellow in 2016.

Her Honors include Lifetime Achievement Awards from the Drexel University SOM Alumni Association in 2012 and from the Child Neurology Society in 2015 and Best Doctors in America 2005-2020 and Best Doctors in Pittsburgh 2013-2020.

Professional and Scientific Society Memberships

  • American Academy of Pediatrics, Fellow, 1974-2011
  • Child Neurology Society, 1975-Present
  • American Academy of Neurology, 1976-Present
    • Fellow, 2016
  • American EEG Society (American Clinical Neurophysiology Society), 1976
  • Pittsburgh Neuroscience Society, 1976
  • American Epilepsy Society, 1978-Present
  • Central EEG Society, 1984
  • American Neurological Association, 2011-Present

Education & Training

  • BS, Biology, Marietta College, 1964
  • MD, Medical College of Pennsylvania, 1968
  • Internship in Pediatrics, Cleveland Metropolitan General Hospital of Western Reserve, 1968-1969
  • Residency in Pediatrics, Cleveland Metropolitan General Hospital of Western Reserve, 1969-1971
  • Fellowship in Pediatric Neurology, College of Physicians and Surgeons Columbia Presbyterian Medical Center, 1971-1974

Selected Publications

Crumrine PK. Degenerative disorders of the central nervous system. Pediatrics in Review 2001; Nov 22(11):370-9, 2001 PMID: 11691947

Crumrine, PK Antiepileptic Drug Selection in Pediatric Epilepsy. Journal of Child Neurology;2002 February 17 Suppl 2:2S2-2S8. DOI: 10.1177/08830738020170020701

Crumrine, PK. Lennox-Gastaut Syndrome. J Child Neurol 2002 Jan 17 Suppl 1:S70-S75. DOI: 10.1177/08830738020170011001

Hirtz, D, Berg, A, Bettis, D, Camfield, C, Camfield, P, Crumrine, PK,Gaillard, WD, Schneider, S,Shinnar, S. Practice Parameter: Treatment of the Child With A First Unprovoked Seizure.   Neurology 2003: 60 (2) 166-175. DOI: 10.1212/01.wnl.0000033622.27961.b6

Kochanek PM, Vagni VA, Janesko KL, Washington CB, Crumrine PK, Garman RH, Jenkins LW, Clark RS, B Homanics GE, Dixon CE, Schnermann J, Jackson EK: Adenosine Al receptor knockout mice develop lethal status epilepticus after experimental traumatic brain injury. J Cereb Blood Flow Metab 26:565-575, 2006. DOI: 10.1038/sj.jcbfm.9600218 

Faulkner LR, Tivnan PW, Johnston MV, Aminoff MJ, Coyle PIC, Crumrine PK, Dekosky ST, Jozefowicz R, Massey JM, Pascuzzi RM. Invited Article: The ABPN Maintenance of certification program for neurologists: past, present, and future. Neurology 2008 Aug 19;71(8):599604.  DOI: 10.1212/01.wnl.0000310815.29495.85

Glauser TA, Cnaan A, Shinnar S, Hirtz DA, Dlugos, Masur D, Clark PO Capparelli EV, Adamson PC and Childhood Absence Epilepsy Study Group. Ethosuximide, Valproic Acid and Lamotrigine in Childhood Absence Epilepsy. N EngJn Med  2010 Mar 4;362(9): 790-799.  

Crumrine PK.  Management of Seizures in the Lennox-Gastaut Syndrome. Pediatric Drugs 2011;13(2):107-118. DOI: 10.2165/11536940-000000000-00000

LR Faulkner,  D Juul,  RM  Pascuzzi. MJ Aminoff,  PK Crumrine,ST Dekosky, RF ozefowicz, JM Massey, N Pirzada, A Tilton. Trends in American Board of Psychiatry and Neurology specialties and neurologic subspecialties. Neurology. 2010; 75(12):1110-7 . DOI: 10.1212/WNL.0b013e3181f39a41

Asato MR, Nawarawong N, Hermann B, Crumrine PK, Luna B. Deficits in oculomotor performance in pediatric epilepsy. Epilepsia 2011; 52(2): 377-385. DOI: 10.1111/j.1528-1167.2010.02787.x



Academic and Research Interests

  • Epilepsy
  • Child Neurology
  • Electroencephalography