Paul Fadakar, M.D.

  • Assistant Professor of Pediatrics

PaulĀ Fadakar primary clinical and academic interest is in kidney transplantation. During his fellowship at CHP, he studied transplant immunology in the lab of Dr. Diana Metes at the Thomas E. Starzl Transplantation Institute. He contributed to the ongoing translational research projects in human immunology investigating the role of T follicular helper cells in the pathophysiology of antibody-mediated rejection in kidney transplant recipients. As a faculty member, his goal is to learn how we can improve the outcomes of our transplant patients. Dr. Fadakar is currently working on a quality improvement initiative to implement an education program that teaches CHP adolescent patients to take ownership of their post-transplant care and facilitates the eventual transition of their care to an adult nephrologist. IHe is also reporting some of the unique cases from the transplant cohort, including a series of patients with antibody-mediated rejection.

Representative Publications

Fadakar P, Yamada M, Hadi K, Macedo C, Metes D. The Effect of Regulatory T cells on the Interaction of T Follicular Helper Cells and Memory B Cells During Plasmablast Formation. (Poster, 2016 American Society of Nephrology, American Transplant Congress)

Fadakar P, Ganoza A, Humar A, Mangiola M, Zeevi A, Nguyen C. Late Antibody-Mediated Rejection After Alemtuzumab Induction in Pediatric Kidney Transplant Recipients - A Single Center Study. (Poster, 2017 International Pediatric Transplant Association Congress)

Macedo C, Fadakar P, Yamada M, Hadi K, Metes D. Indirect Allo-antigen Stimulation Identifies Presence of Either Regulatory IL-10 or of Effector Cytokine IFN-Ī³, IL-21, IL-17 Production by Human Blood Allo-reactive Memory TFH and TCONV CD4+ T cells. (Poster, 2016 American Transplantation Congress).

Yamada M, Fadakar P, Nguyen C, Michaels M, Green M. Chronic High Epstein-Barr Viral Load Carriage in Pediatric Kidney Transplant Recipients. (Poster, 2016 American Transplantation Congress)