University of Pittsburgh logo

Sapana J. Shah, MD

  • Assistant Professor of Pediatrics

Shah attended medical school at Sidney Kimmel Medical College of Thomas Jefferson University, completed her Pediatrics residency at UPMC Children’s Hospital of Pittsburgh/University of Pittsburgh School of Medicine, and completed her Pediatric Gastroenterology fellowship at UPMC Children’s Hospital of Pittsburgh/University of Pittsburgh School of Medicine. She has been faculty of the Division of Gastroenterology, Hepatology, and Nutrition at UPMC Children’s Hospital of Pittsburgh since 2012. Her primary clinical and academic interest is in pediatric inflammatory bowel disease. She is the site primary investigator for Improve Care Now (ICN), a multicenter pediatric inflammatory bowel disease quality improvement network. She is also site PI for NIH-funded and industry funded pediatric inflammatory bowel disease research studies.

Professional and Scientific Society Membership

  • NASPGHAN, 2009-Present
  • Crohn's and Colitis Foundation, 2018-Present

Education & Training

  • BS, Pre-Medical Studies, Pennsylvania State University, 2002
  • MD, Sidney Kimmal Medical College of Thomas Jefferson University, 2006
  • Residency in Pediatrics, UPMC Children's Hospital of Pittsburgh, 2006-2009
  • Fellowship in Pediatric Endocrinology, UPMC Children's Hospital of Pittsburgh, 2009-2012

Selected Publications

Tokarz R, Hyams JS, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Shah S, Markowitz J, Baker SS, Rosh J, Baldassano RN, Kugathasan S, Walters T, Tagliafierro T, Sameroff S, Lee B, Che X, Oleynik A, Denson LA, Lipkin WI.  Characterization of Stool Virome in Children Newly Diagnosed With Moderate to Severe Ulcerative Colitis.  Inflamm Bowel Dis. 2019 May 21

Haberman Y, Karns R, Dexheimer PJ, Schirmer M, Somekh J, Jurickova I, Braun T, Novak E, Bauman L, Collins MH, Mo A, Rosen MJ, Bonkowski E, Gotman N, Marquis A, Nistel M, Rufo PA, Baker SS, Sauer CG, Markowitz J, Pfefferkorn MD, Rosh JR, Boyle BM, Mack DR, Baldassano RN, Shah S, Leleiko NS, Heyman MB, Grifiths AM, Patel AS, Noe JD, Aronow BJ, Kugathasan S, Walters TD, Gibson G, Thomas SD, Mollen K, Shen-Orr S, Huttenhower C, Xavier RJ, Hyams JS, Denson LA.  Ulcerative colitis mucosal transcriptomes reveal mitochondriopathy and personalized mechanisms underlying disease severity and treatment response.  Nat Commun. 2019 Jan 3;10(1):38

Yeung JT, Pollack IF, Shah S, Jaffe R, Nikiforova M, Jakacki RI.  Optic pathway glioma as part of a constitutional mismatch-repair deficiency syndrome in a patient meeting the criteria for neurofibromatosis type 1. Pediatr Blood Cancer. 2013; 60:137-9.

Good M, Siggers RH, Sodhi CP, Afrazi A, Alkhudari F, Egan CE, Neal MD, Yazji I, Jia H, Lin J, Branca MF, Ma C, Prindle T, Grant Z, Shah S, Slagle D 2nd, Paredes J, Ozolek J, Gittes GK, Hackam DJ. Amniotic fluid inhibits Toll-like receptor 4 signaling in the fetal and neonatal intestinal epithelium. PNAS. 2012; 109:11330-5

Full Publication List via NIH PubMed »