Simon Horslen, MBChB, FRCPCH

  • Professor of Pediatrics
  • Director of Pediatric Hepatology, UPMC Children's Hospital of Pittsburgh

Administrative Assistant: Stefanie Tavormina

Horslen is Director of Hepatology, in the Division of Gastroenterology at UPMC Children’s Hospital of Pittsburgh Horslen is a British trained physician, completing Medical School at the University of Bristol Medical School. He completed his training in General Pediatrics and Pediatric Hepatology and Gastroenterology in UK before being recruited to University of Nebraska as a Pediatric Hepatologist and Transplant physician in 1997. In 2004 Horslen was recruited to Seattle Children’s Hospital as Medical Director for Liver and Intestine Transplantation. He established the intestinal rehabilitation program and was Director of the Hepatobiliary Program. He was a Professor in the Department of Pediatrics at the University of Washington. Research interests include acute liver failure, metabolic liver disease, intestinal failure and liver and intestine transplantation. He has published over 150 articles, reviews, editorials and chapters. He has been Chair of OPTN Pediatric Committee and a member of the UNOS/OPTN Board of Governors. He has been President of the Society for Pediatric Liver Transplantation and the Intestinal Rehabilitation and Transplantation Association. He is a Fellow of the Royal College of Paediatrics and Child Health (UK), the American Society of Transplantation and of the American Association for Study of Liver Disease.

Professional and Scientific Society Memberships:

  • Royal College of Pediatrics and Child Health, 1997-Present
  • American Association for the Study, 1999-Present
  • American Society of Transplantation, 2000-Present
  • North American Society of Pediatric Gastroenterology and Nutrition, 2000-Present
  • United Network for Organ Sharing, 2001-Present
  • International Pediatric Transplantation Society, 2002-Present
  • Society of Pediatric Research, 2003-2009
  • Intestinal Rehabilitation and Transplantation Association, 2004-Present
  • American Pediatric Society, 2006-Present
  • The Transplantation Society, 2017-Present

Education & Training

  • MB, ChB, University of Bristol Medical School, United Kingdom, 1984

Selected Publications

Chapin CA, Horslen SP, Squires JE, Lin H, Blondet N, Mohammad S, Alonso EM. Corticosteroid Therapy for Indeterminate Pediatric Acute Liver Failure and Aplastic Anemia with Acute Hepatitis. J Pediatr. 2019 May;208:23-29. doi: 10.1016/j.jpeds.2018.12.042. Epub 2019 Feb 13. PMID: 30770193 

Perito ER, Mogul DB, VanDerwerken D, Mazariegos G, Bucuvalas J, Book L, Horslen S, Kim HB, Miloh T, Ng V, Reyes J, Rodriguez-Davalos MI, Valentino PL, Gentry S, Hsu E. The Impact of Increased Allocation Priority for Children Awaiting Liver Transplant: A Liver Simulated Allocation Model (LSAM) Analysis. J Pediatr Gastroenterol Nutr. 2019 Apr;68(4):472-479. doi: 10.1097/MPG.0000000000002287. PMID: 30720563 

Fischler B, Baumann U, D'Agostino D, D'Antiga L, Dezsofi A, Debray D, Durmaz O, Evans H, Frauca E, Hadzic N, Jahnel J, Loveland J, McLin V, Ng VL, Nobili V, Pawłowska J, Sharif K, Smets F, Verkade HJ, Hsu E, Horslen S, Bucuvalas J. Similarities and Differences in Allocation Policies for Pediatric Liver Transplantation Across the World. J Pediatr Gastroenterol Nutr. 2019 May;68(5):700-705. doi: 10.1097/MPG.0000000000002283. PMID: 30676519

Newland DM, Royston MJ, McDonald DR, Nemeth TL, Wallace-Boughter K, Carlin K, Horslen S. Analysis of rabbit anti-thymocyte globulin vs basiliximab induction in pediatric liver transplant recipients. Pediatr Transplant. 2019 Dec;23(8):e13573. doi: 10.1111/petr.13573. [Epub ahead of print] PMID: 31512802

Kocoshis SA, Merritt RJ, Hill S, Protheroe S, Carter BA, Horslen S, Hu S, Kaufman SS, Mercer DF, Pakarinen MP, Venick RS, Wales PW, Grimm AA. Safety and Efficacy of Teduglutide in Pediatric Patients With Intestinal Failure due to Short Bowel Syndrome: A 24-Week, Phase III Study. JPEN J Parenter Enteral Nutr. 2019 Sep 8. doi: 10.1002/jpen.1690. [Epub ahead of print] PMID: 31495952

Ng VL, Mazariegos GV, Kelly B, Horslen S, McDiarmid SV, Magee JC, Loomes KM, Fischer RT, Sundaram SS, Lai JC, Te HS, Bucuvalas JC. Barriers to ideal outcomes after pediatric liver transplantation. Pediatr Transplant. 2019 Sep;23(6):e13537. doi: 10.1111/petr.13537. Epub 2019 Jul 25. PMID: 31343109 

Neam VC, Oron AP, Nair D, Edwards T, Horslen SP, Javid PJ. Factors Associated with Health-Related Quality of Life in Children with Intestinal Failure. J Pediatr. 2020 Jan;216:13-18.e1. doi: 10.1016/j.jpeds.2019.08.049. Epub 2019 Oct 4. PMID: 31590945 

Elisofon SA, Magee JC, Ng VL, Horslen SP, Fioravanti V, Economides J, Erinjeri J, Anand R, Mazariegos GV; Society of Pediatric Liver Transplantation Research Group. Society of pediatric liver transplantation: Current registry status 2011-2018. Pediatr Transplant. 2019 Nov 3:e13605. doi: 10.1111/petr.13605. [Epub ahead of print] PMID: 31680409  

Smith JM, Weaver T, Skeans MA, Horslen SP, Miller E, Noreen SM, Snyder JJ, Israni AK, Kasiske BL. OPTN/SRTR 2018 Annual Data Report: Intestine. Am J Transplant. 2020 Jan;20 Suppl s1:300-339. doi: 10.1111/ajt.15675. PMID: 31898410

Chapin CA, Horslen SP, Squires JE, Lin H, Blondet N, Mohammad S, Alonso EM. Corticosteroid Therapy for Indeterminate Pediatric Acute Liver Failure and Aplastic Anemia with Acute Hepatitis. Accepted by: The Journal of Pediatrics. December 2018