Stacey Drant, M.D.

  • Associate Professor of Pediatrics 
  • Director, Noninvasive Imaging

Professional Affiliations/Society Memberships

  • American Society of Echocardiography

Education & Training

  • MD: Brown University Alpert School of Medicine Providence, RI
  • Residency: David Geffen School of Medicine at UCLA Los Angeles, CA
  • Fellowship: David Geffen School of Medicine at UCLA Los Angeles, CA

Research Interests

Aortic Stiffness in Aortic Root Dilatation. A subgroup of patients with bicuspid aortic valve develops aortic dilatation during childhood and is at increased risk for aortic dissection during adulthood. Patients with other forms of aortic dilatation have been found to have abnormal aortic elastic qualities. Using echocardiography to measure aortic distensibility and stiffness, Stacey Drant’s team is evaluating normal pediatric patients and those with a bicuspid aortic valve to identify patients who will be at increased risk for future aortic dissection and assess response to medical therapy.

National Clinical Trial of Beta Blocker Therapy (Atenolol) Versus Angiotension II Receptor Blocker Therapy (Losartan) in Individuals with Marfan Syndrome. Drant is the site principal investigator and the primary aim is to compare the effect of atenolol therapy to that of losartan therapy on the rate of aortic growth and progression of aortic regurgitation.

Use of the MPI Derived by Echocardiography to Identify Rejection in Patients after Heart Transplant. Standard, noninvasive imaging has not proven to be very effective in identifying patients with rejection following heart transplantation. The MPI, derived through Doppler and tissue Doppler measurements, has been used to measure subtle forms of myocardial dysfunction. This retrospective study used a large transplant database and confirmed that the MPI calculated with spectral Doppler predicts cardiac transplant rejection. Ongoing studies will utilize tissue Doppler indices to measure MPI in a prospective fashion.

Exercise Training on Sedentary Obese Pediatric Patients. Drant is overseeing a study that assesses the effects of exercise training on left ventricular mass in sedentary obese pediatric patients.