Terence S. Dermody, M.D.

  • Vira I. Heinz Professor and Chair, Department of Pediatrics
  • Professor of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine
  • Physician-in-Chief and Scientific Director, UPMC Children’s Hospital of Pittsburgh

Terence S. Dermody, M.D., is the Vira I. Heinz Professor and Chair of the Department of Pediatrics at the University of Pittsburgh School of Medicine as well as Professor of Microbiology and Molecular Genetics. He also is physician-in-chief and scientific director of UPMC Children's Hospital of Pittsburgh. Dr. Dermody is a virologist with interests in viral pathogenesis and vaccine development. He has focused mainly on reovirus, an important experimental model for studies of viral encephalitis in infants, and on chikungunya virus, an arthropod-borne virus that causes epidemics of febrile arthritis.

The work in Dr. Dermody's lab has encompassed several inter-related themes including the structural basis of viral attachment and cell entry; mechanisms of genome replication and packaging; patterns of cell signaling and gene expression occurring in response to viral infection; mechanisms of virus-induced apoptosis and its significance in the viral life cycle; and the role of viral receptor distribution and utilization in disease pathology. The lab also is developing viral vectors for oncolytic and vaccine applications.

He joined Children's Hospital from Vanderbilt University, where he was the Dorothy Overall Wells Professor of Pediatrics, director of the Division of Pediatric Infectious Diseases, director of the Medical Scientist Training Program, director of the Elizabeth B. Lamb Center and Professor of Pathology, Microbiology and Immunology.

He has authored or co-authored more than 240 articles, reviews, and chapters about his research, which is supported in large part by grants from the National Institutes of Health (NIH). He is a member of several editorial boards. He has been recognized for his research accomplishments with the Ernest W. Goodpasture Faculty Research Award, the Grant W. Liddle Award for Leadership in the Promotion of Scientific Research, and an NIH MERIT Award. He is a past president of the American Society for Virology, past chair of the AAMC GREAT Group M.D./Ph.D. Section Steering Committee, and current chair of the Virology Division of the International Union of Microbiological Societies.

Professional Affiliations/Society Memberships

  • Fellow, Infectious Diseases Society of America
  • Fellow, American College of Physicians
  • American Society for Clinical Investigation
  • Society for Pediatric Research
  • Association of American Physicians
  • Fellow, American Academy of Microbiology
  • American Pediatric Society
  • Fellow, American Association for the Advancement of Science
  • Fellow, Pediatric Infectious Diseases Society

Advisory Committee Appointments

  • Chair Management Committee, UPMC
  • University of Pittsburgh Physicians Council of Clinical Chairs, UPMC
  • Board of Trustees, UPMC Children’s Hospital of Pittsburgh
  • Executive Staff, UPMC Children’s Hospital of Pittsburgh
  • Chair, Research Strategic Planning Committee, UPMC Children’s Hospital of Pittsburgh
  • Faculty Executive Committee, University of Pittsburgh School of Medicine
  • Search Committee, Center for Vaccine Research
  • Chair, Appointments and Promotions Committee, University of Pittsburgh Department of Pediatrics
  • Chair, Research Advisory Committee, University of Pittsburgh Department of Pediatrics
  • Chair, Virology Division, International Union of Microbiological Societies
  • Reoviridae Study Group, International Committee on Taxonomy of Viruses
  • Board of Governors, American Academy of Microbiology
  • Board of Directors, Burroughs Wellcome Fund
  • Medical Scientist Training Program, University of Cincinnati College of Medicine
  • MD-PhD Training Program, University of Florida College of Medicine
  • Scientific Advisory Committee, Autophagy Modulators as Novel Broad-Spectrum Anti-infective Agents, Center of Excellence for Translational Research, Washington University, St. Louis, Mo.
  • Medical Scientist Training Program, Duke University School of Medicine
  • Molecular Dissection of Norovirus Replication and Pathogenesis to Develop Therapeutics, Baylor College of Medicine
  • Scientific Program Vice-Chair, 17th International Congress of Virology, Singapore, 2017
  • Board of Directors, Burroughs Wellcome Fund

Editorial Boards

  • Editor, Journal of Virology
  • Spotlight Editor, Journal of Virology
  • Member, Biology, Microbiology Faculty, Virology Section, Faculty of 1000
  • Editor, mBio
  • Associate Editor, Annual Review of Virology

Education & Training

  • Fellowship: Harvard Medical School, Boston, MA
  • Residency: Presbyterian Hospital of New York, New York, NY
  • MD: Columbia University, New York, NY
  • BS: Cornell University, Ithaca, NY

Representative Publications

Division

Lab