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Tsuyoshi Fujita, MD, PhD

  • Fellow

Tsuyoshi Fujita, MD, PhD, has always been intrigued by how bodies fight against diseases and the complexities of the immune system. His goal is to understand how the systems work against cancers through research and caring for patients with cancers.

Resident Biographical Details

Hometown

Kagoshima, Japan

College or Medical School

Tohoku University School of Medicine

Hobbies and Interests

Enjoys music including metal/rock/classical and base guitar, and always loves to be a dog sitter for friends.

Personal Details

Just adopted a dog.

Travel Interests and Languages

Japanese and learning Spanish

"Likes" about UPMC Children's Hospital of Pittsburgh

Great education system and a lot of autonomy with safe structure. Nice food, nice people, nice place, nice life.

Interesting Fact

I was a professional bass guitar player in Japan.

Education & Training

  • MD-PhD, Tohoku University School of Medicine 2017
  • PhD, Immunology, Tohoku University Graduate School of Medicine 2015

Selected Publications

D'Antoni ML, Kallianpur KJ, Premeaux TA, Corley MJ, Fujita T, Laws EI, Ogata-Arakaki D, Chow DC, Khadka VS, Shikuma CM, Ndhlovu LC. “Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection.”  Frontiers in Immunology. 2019, Nov;10:2789

Hoffmann PR , Hoffmann FW , Premeaux TA , Fujita T, Soprana E , Panigada M , Chew GM , Richard G , Hindocha P , Menor M , Khadka VS , Deng Y , Moise L , Ndhlovu LC , Siccardi A, Weinberg AD, De Groot AS , Bertino P. “Multi-antigen Vaccination With Simultaneous Engagement of the OX40 Receptor Delays Malignant Mesothelioma Growth and Increases Survival in Animal Models.” Front Oncol. 2019, Aug 2;9:720

Bernito P,  Premeaux TA , Fujita T, Haun BK, Marciel MP, Hoffmann FW, Garcia A, Yiang H, Pastriano S, Carbone M, Niki T, Berestecjy J, Hoffmann PR, Ndhlovu LC. 2019 “Targeting the C-terminus of Galectin-9 Induces Mesothelioma Apoptosis and M2 Macrophage Depletion.” Oncoimmunology 17; 8(8):1601482

Nagashima H, Okuyama Y,  Fujita T, Takeda T, Motomura Y, Moro K, Hidaka T, Omori K, Sakurai T, Machiyama T, Ndhlovu LC, Riccardi C, So T, Ishii N. 2018. ”GITR Cosignal in ILC2 Controls Allergic Lung Inflammation.” J Allergy Clin Immunol.2018 May; 141(5):1939-1943.e8.

Fujita T, Ichikawa S, Okitsu Y, Fukuhara N, Yoshinaga T, Yazaki M, Harigae H. 2016. “Primary AL amyloidosis presenting with systemic lymphadenopathy with calcification.” Int J Hematol. 2016 Dec;104(6):641-643.

Chew GM, Fujita T, Webb GM, Burwitz BJ, Wu HL, Reed JS, Hammond KB, Clayton KL, Ishii N, Abdel-Mohsen M, Liegler T, Mitchell BI, Hecht FM, Ostrowski M, Shikuma CM, Hansen SG, Mauer M, Korman AJ, Deeks SG, Sacha JB, Ndhlovu LC. 2016. “TIGIT Marks Exhausted T Cells, Correlates with Disease Progression, and Serves as a Target for Immune Restoration in HIV and SIV Infection.” PLoS Pathog. 2016 Jan 7;12(1):e1005349.

Fujita T, Burwitz BJ, Chew GM, Reed JS, Pathak R, Seger E, Clayton KL, Rini JM, Ostrowski MA, IshiiN, Kuroda MJ, Hansen SG, Sacha JB, Ndhlovu LC. 2014. “Expansion of dysfunctional Tim-3-expressing effector memory CD8+ T cells during simian immunodeficiency virus infection in rhesus macaques.” J Immunol. 2014 Dec 1;193(11):5576-83

Kawabe T, Sun SL, Fujita T, Yamaki S, Asao A, Takahashi T, So T, Ishii N. 2013. ”Homeostatic Proliferation of naïve CD4+ T cells in mesenteric lymph nodes generates gut-tropic Th17 cells.” J Immunol. 2013 Jun 1;190(11):5788-98.

Ndhlovu LC, Lopez-Verges S, Barbour JD, Jones RB, Jha AR, Long BR, Schoeffler EC, Fujita T, Nixon DF, Lanier LL. 2012.” Tim-3 marks human natural killer cell maturation and suppresses cell-mediated cytotoxicity.” Blood. 2012 Apr 19;119(16):3734-43