William Pequignot Welch, MD

  • Assistant Professor of Pediatrics

Administrative Assistant: Melissa White

Welch is an Assistant Professor of Pediatrics in the Division of Neurology and Child Development Unit, Director of Epilepsy Neurostimulation, and Associate Director of the Epilepsy Surgery Program at UPMC Children's Hospital of Pittsburgh. In his clinical practice, he specializes in electroencephalography and the treatment of pediatric epilepsy. His research interests include pediatric epilepsy, epilepsy surgery, neurostimulation, and epilepsy genetics. Welch received his Bachelor of Arts, Bachelor of Science, and Doctor of Medicine from the University of Oklahoma. He completed Child Neurology residency Epilepsy Fellowship at UPMC Children's Hospital of Pittsburgh.

Professional and Scientific Society Memberships

  • International League Against Epilepsy, 2018-Present
  • Child Neurology Society, 2017-Present
  • American Epilepsy Society, 2015-Present
  • American Academy of Neurology, 2015-Present

Education & Training

  • BS, Zoology, University of Oklahoma, 2008
  • BA, English Literary and Cultural Studies, University of Oklahoma, 2008
  • MD, University of Oklahoma, 2013
  • Residency in Pediatrics, UPMC Children's Hospital of Pittsburgh, 2013-2015
  • Residency in Child Neurology, UPMC Children's Hospital of Pittsburgh, 2015-2018
  • Fellowship in Epilepsy, UPMC Department of Neurology, 2018-2019

Selected Publications

Curtis K, Hect JL, Harford E, Welch WP, Abel TJ. Responsive neurostimulation for pediatric drug resistant epilepsy: a case series and review of the literature. Neurosurgical Focus. 2022;53(4):E10. PubMed PMID 36183183

Muthiah N, Mallela AN, Vodovotz L, Sharma N, Akwayena E, Pan E, Welch W, Ibrahim GM, Abel TJ. Development of a clinical model to predict vagus nerve stimulation response in pediatric patients with drug-resistant epilepsy. Journal of Neurosurgery: Pediatrics. 2023 Feb 17;1(aop):1-8

Muthiah N, Zhang J, Remick M, Welch WP, Sogawa Y, Jeong JH, Abel TJ. Efficacy of vagus nerve stimulation for drug-resistant epilepsy in children age six and younger. Epilepsy Behav. 2020 Nov; 112:107373.

Edmonds BD, Welch W, Sogawa Y, Mountz J, Bagic A, Patterson C. The Role of Magnetoencephalography and Single-Photon Emission Computed Tomography in Evaluation of Children With Drug-Resistant Epilepsy. Journal of Child Neurology. 2021;36(8):673-9. doi: 10.1177/0883073821996558. PubMed PMID: WOS:000637126400001.

Welch WP, Hect JL, Abel TJ. Case Report: Responsive Neurostimulation of the Centromedian Thalamic Nucleus for the Detection and Treatment of Seizures in Pediatric Primary Generalized Epilepsy. Front Neurol. 2021 Apr; 12:656585.

Abel TJ, Remick M, Welch WP, Smith KJ. One-year cost-effectiveness of callosotomy vs vagus nerve stimulation for drug-resistant seizures in Lennox-Gastaut Syndrome: A decision analytic model. Epilepsia Open. 2021 Dec 10. doi: 10.1002/epi4.12570. Epub ahead of print. PMID: 34890113.

Hect JL, Fernandez LD, Welch WP, Abel TJ. Deep Brain Stimulation of the Centromedian Thalamic Nucleus for the Treatment of FIRES. Epilepsia Open. 2021 Dec 4. PubMed PMID 34862854.

Bohm RA, Welch WP, Goodnight LK, Cox LW, Henry LG, Gunter TC, Bao H, Zhang B. A genetic mosaic approach for neural circuit mapping in Drosophila. Proceedings of the National Academy of Sciences. 2010 Sept 14;107(37):16378-83. PubMed PMID: 20810922

Fore TR, Ojwang AA, Warner ML, Peng X, Bohm RA, Welch WP, Goodnight, LK, Bao H, Zhang B. Mapping and application of enhancer-trap flippase expression in larval and adult Drosophila CNS. J Vis Exp. 2011 Jun 3;(52):2649. PubMed PMID: 21673643

Huang P, Sahai-Hernandez P, Bohm R, Welch WP, Zhang B, Nystul T. Enhancer-trap flippase lines for clonal analysis in the Drosophila ovary. G3 (Bethesda). 2014 Sept; 4(9):1693-99. PubMed PMID: 25024257

 

 

Academic and Research Interests

  • Epilepsy
  • Epilepsy Surgery
  • Neurostimulation 
  • Epilepsy Genetics