Our Equipment

LC/MS/MS (Tandem Mass Spectrometry)

AB Sciex® API 4000
Triple quadrupole mass spectrometer for small molecule analysis

  • Metabolic profiling (concentration; µM) of acylcarnitines (54), amino acids (9), S-adenosylmethionine/S-adenosylhomocysteine (SAM/SAH), and other metabolism pathways 
  • Inquire about a new assay for your pathway metabolites 

Seahorse Extracellular Flux (XF) Assays

Agilent® Seahorse(TM) XFe96 Analyzer 
Measurement of mitochondrial function and/or glycolytic activity via:

  • oxygen consumption rate (OCR)
  • extracellular acidification rate (ECAR) 

7 kits available: Cell Mito Stress, Glycolysis Stress, Glycolytic Rate, ATP Rate, Cell Energy Phenotype, Mito Fuel Flex, FAO Substrate

NOTE: The XF Cell Mito Stress Test kit is included in the Core-provided supplies; all other XF kits (6) are Customer-purchased kits.  

Manufacturer Information

Reverse-Phase HPLC System 

Waters® Alliance Separations Module
with 3 detectors – UV (PDA), fluorescence, and electrochemical 

  • Analysis of drugs or metabolites
    • Monoamine metabolites - New qualified assay for 5-HIAA (5-hydroxyindoleacetic acid), metabolite of Serotonin (5-HT, 5-hydroxytryptamine) 
  • Flux studies (substrate vs product)