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Burhan Mahmood, MD, FAAP

  • Professor of Pediatrics, Neonatal-Perinatal Medicine
  • Medical Director, Newborn Medicine ECMO Program, UPMC Children's Hospital of Pittsburgh
  • Director, Newborn Medicine CDH Program, UPMC Children's Hospital of Pittsburgh

Dr. Mahmood serves as the Medical Director of the Neonatal Extracorporeal Membrane Oxygenation (ECMO) and Congenital Diaphragmatic Hernia (CDH) Programs at UPMC Children’s Hospital of Pittsburgh. He directs the Neonatal ECMO Curriculum for the UPMC Division of Newborn Medicine that encompasses wet labs, monthly conferences, ECMO simulation, equipment reviews, quality improvement initiatives, research and QI projects, didactic sessions and ECMO patient case reviews. He also directs the Neonatal-Perinatal Fellowship Advanced ECMO Training Program for the neonatology fellows, initiated in 2019. Dr. Mahmood is involved with many other educational activities within the UPMC Division of Newborn Medicine and serves as Instructor Mentor for the Neonatal Resuscitation Program at University of Pittsburgh. He also conducts the Neonatal Transition Curriculum for the Reproductive and Developmental Biology Course at University of Pittsburgh School of Medicine. 

Dr. Mahmood has keen interest in research, presenting multiple basic science projects at scientific meetings during early part of his career. Thereafter he initiated several IRB-approved clinical research projects in collaboration with other divisions within the department of pediatrics that were presented at scientific meetings. Dr. Mahmood has provided research mentorship to several neonatology fellows for their clinical research and QI projects with their work published and presented at national and international meetings. He has also participated as co-investigator in several other IRB-approved multi-center studies. 

Dr. Mahmood’s primary research interest is in the area of Neonatal ECMO Support, Congenital Diaphragmatic Hernia Management and Neonatal Cardio-respiratory Failure to better understand the nuances of disease process with goal to improve outcomes and patient care. For this end, he represents UPMC Children’s Hospital of Pittsburgh nationally at the Children’s Hospital Neonatal Consortium (CHNC) Congenital Diaphragmatic Hernia and ECMO focus groups. In collaboration with representatives from other CHNC centers these groups utilize Children’s Hospitals Neonatal Database (CHND) to better understand disease process, inter-center variations in clinical management practices and overall patient outcomes to help standardize care. Nationally, Dr. Mahmood continues to actively participate in both the CHNC focus groups, leading as well as collaborating in multiple research projects that have been published and presented as scientific meetings. He serves as Scientific Reviewer for the Clinical Investigation Committee within UPMC Division of Newborn Medicine at the University of Pittsburgh. He was appointed as member of the Society for Pediatric Researchin 2023.

Professional and Scientific Society Memberships

  • American Academy of Pediatrics
  • Children's Hospitals Neonatal Consortium
  • AAP - Section on Neonatal-Perinatal Medicine
  • AAP Section on International Medical Graduates
  • Society for Pediatric Research

Education & Training

  • MBBS, Aga Khan University Medical College, 1991
  • Internship in Pediatrics, Aga Khan University Hospital, 1991-1992
  • Internship in Surgery, Aga Khan University Hospital, 1992
  • Residency in Pediatrics, The Pennsylvania State University, Milton S. Hershey Medical Center, 1994-1997
  • Fellowship in Neonatal-Perinatal Medicine, UPMC Children's Hospital of Pittsburgh and UPMC Magee-Womens Hospital, 1997-2000

Selected Publications

 

Mahmood B. Persistent pulmonary hypertension of newborn. Seminars Pediatric Surgery 2022 Aug;31(4):151202. PMID: 36038220

Ibrahim J, Mahmood B, DiGeronimo R, Rintoul N, Shannon H, Chapman R, Keene S, Dirnberger D. Children's Hospitals Neonatal Consortium ECMO Focus Group. Ventilation Strategies during Extracorporeal Membrane Oxygenation for Neonatal Respiratory Failure: Current Approaches Among Level IV NICUs. Crit Care Explor. 2022 Nov 15;4(11): e0779. PMID: 36406885

Wild T, Miquel-Verges F, Rintoul N, DiGeronimo R, Keene S, Hamrick SE, Mahmood B, Seabrook R, Rao R, Carr N; Children's Hospitals Neonatal Consortium ECMO Focus Group. Current Practices for Genetic Testing in Neonatal Extracorporeal Membrane Oxygenation: Findings from a National Survey. Perfusion. 2022 Sep 28:2676591221130178. PMID: 36169593.

 Grover TR, Weems MF, Brozanski B, Daniel J, Haberman B, Rintoul N, Walden A, Hedrick H, Mahmood B, Seabrook R, Murthy K, Zaniletti I, Keene S; Children's Hospitals Neonatal Consortium CDH Focus Group. Central Line Utilization and Complications in Infants with Congenital Diaphragmatic Hernia. Am J Perinatology. 2022 Oct;29(14):1524-1532. PMID: 33535242

Porta NF, Naing K, Keene S, Grover TR, Hedrick H, Mahmood B, Seabrook R, Daniel J, Harrison A, Weems M, DiGeronimo R, Haberman B, Dariya V, Guner Y, Rintoul N, Murthy K; Children's Hospitals Neonatal Consortium CDH Focus Group. Variability for Age at Successful Extubation in Infants with Congenital Diaphragmatic Hernia. J Pediatr. 2022 Oct 3:S0022-3476(22)00853-8. PMID: 36202240.

Lichtsinn K, Waltz P, Azzuqa A, Church J, Graham J, Troutman J, Mahmood B. Impact of a standardized management guideline for infants with CDH: A single-center experience. J Pediatr Surg. 2023 Mar;58(3):389-396. PMID: 35965150.

Lichtsinn K, Church J, Waltz P, Azzuqa A, Graham J, Troutman J, Mahmood B. Clinical variables associated with ECMO use and mortality in infants with CDH: A single-center experience. J Pediatr Surg Open. Volume 3, May 2023, 100027

Linden A, Howk A, Billimoria Z, Devine M, DiGeronimo B, Gray B, Hamrick S, Keene S, Rintoul N, Mahmood B; Children's Hospital Neonatal Consortium (CHNC). Neonatal carotid artery and internal jugular vein management practices at extracorporeal membrane oxygenation decannulation: No standard approach. J Pediatr Surg. 2023 Jul 24:S0022-3468(23)00408-6. PMID: 37573253.

Lichtsinn K, Church J, Waltz P, Azzuqa A, Graham J, Troutman J, Li R, Mahmood B. Early ventilator management for infants with congenital diaphragmatic hernia: Impact of a standardized clinical practice guideline. J Pediatr Surg. Sept 2023. PMID: 37865575

Sloan P, Johng S, Daniel J, Rhee R, Mahmood B, Gravari E, Marshall S, Downey A, Braski K, Gowda S, Fernandes C, Dariya V, Haberman B, Seabrook R, Makkar A, Gray B, Cookson M, Najaf T, Rintoul N, Hedrick H, Weems M, Ades A, Chapman R, Grover T, Keene S; Children's Hospital Neonatal Consortium CDH Focus Group. A Clinical Consensus Guideline for Nutrition in Infants with Congenital Diaphragmatic Hernia from Birth through Discharge. J Perinatology. April 2024. PMID: 38627594 

Academic and Research Interests

  • Neonatal ECMo Support
  • Congenital Diaphragmatic Herna
  • Neonatal Pulmonary Hypertension