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Sydney Rooney, MD

  • Resident, PGY-3
  • Chief Resident, Pediatric Scientist Development Program

Sydney Rooney, MD is a pediatric resident in her third year of training at UPMC’s Children’s Hospital of Pittsburgh and serves as the Chief Resident to the Pediatric Scientist Development Program. Rooney received her Bachelor of Science degree from Johns Hopkins University and her Doctor of Medicine degree from Vanderbilt University School of Medicine. During her training, Sydney was awarded the Burroughs Wellcome Fund Physician Scientist Incubator and R38 StARR awards, which allowed her to take two research years between her PGY-2 and PGY-3 years. She plans to pursue cardiology fellowship.

Education & Training

  • BS, Johns Hopkins University, 2014
  • MD, Vanderbilt University School of Medicine, 2019
  • Children's Hospital of Pittsburgh Residency, Present

Selected Publications

Mitchell R, Molligan J, Rooney S, Cho Y, Schon L, Zhang Z. Functionally compromised synovium-derived mesenchymal stem cells in Charcot neuroarthropathy. Exp Mol Pathol. 2018; 104(1): 82-88. PMID: 29353045

Rooney SR, Donohue JE, Bush LB, Zhang W, Banerjee M, Pasquali SK, Gaies MG. Extubation failure rates after pediatric cardiac surgery vary across hospitals. Pediatr Crit Care Med. 2019 May; 20(5): 450-456. PMCID: PMC6502690

Rooney SR*, Shelton EL*, Aka I, Shaffer C, Clyman RI, Dagle JM, Ryckman K, Lewis TR, Reese J, Van Driest SL, Kannankeril PJ [*Co-first author]. CYP2C9*2 is Associated with Indomethacin Treatment Failure for Patient Ductus Arteriosus. Pharmacogenomics. 2019; 20:13, 939-946. PMCID: PMC6817966

Rooney SR, Mastropietro CW, Benneyworth B, Graham EM, Klugman D, Costello J, Ghanayem N, Zhang W, Banerjee M, Gaies M. Influence of Early Extubation Location on Outcomes Following Pediatric Cardiac Surgery. Pediatr Crit Care Med. 2020 Oct; 21(10):e915-e92. PMCID: PMC7541477

Rooney SR, Reynolds EL, Banerjee M, Pasquali SK, Charpie JR, Gaies MG, Owens GE. Prediction of extubation failure in the paediatric cardiac ICU using machine learning and high-frequency physiologic data. Cardiol Young. 2021 Dec 20:1-8. doi: 10.1017/S1047951121004959. Epub ahead of print. PMID: 34924086.

Werho DK, Fisk A, Yeh J, Rooney S, Wilkes R, Shin AY, Zhang W, Banerjee M, Gaies M. Measuring Critical Care Unit Performance Using a Postoperative Mechanical Ventilation Quality Metric. Ann Thorac Surg. 2022 Dec 5:S0003-4975(22)01505-3. doi: 10.1016/j.athoracsur.2022.11.026. Epub ahead of print. PMID: 36470563.

Rooney SR, Kaufman R, Murugan R, Kashani KB, Pinsky MR, Al-Zaiti S, Dubrawski A, Clermont G, Miller JK. Forecasting imminent atrial fibrillation in long-term electrocardiogram recordings. J Electrocardiol. 2023 Aug 23;81:111-116. doi: 10.1016/j.jelectrocard.2023.08.011. Epub ahead of print. PMID: 37683575.

Rooney SR, Clermont G. Forecasting algorithms in the ICU. J Electrocardiol. 2023 Oct 4;81:253-257. doi: 10.1016/j.jelectrocard.2023.09.015. Epub ahead of print. PMID: 37883866.

Academic and Research Interests

  • Predictive analytics
  • Cardiology 
  • Waveform
  • Critical care
  • Machine learning